Journal article
Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage
Abstract
BACKGROUND: Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied.
METHODS: We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage to receive …
Authors
Connolly SJ; Sharma M; Cohen AT; Demchuk AM; Członkowska A; Lindgren AG; Molina CA; Bereczki D; Toni D; Seiffge DJ
Journal
New England Journal of Medicine, Vol. 390, No. 19, pp. 1745–1755
Publisher
Massachusetts Medical Society
Publication Date
May 16, 2024
DOI
10.1056/nejmoa2313040
ISSN
0028-4793