Journal article
Network meta-analysis of direct-acting antivirals in combination with peginterferon–ribavirin for previously untreated patients with hepatitis C genotype 1 infection
Abstract
AIM: To conduct a network meta-analysis (NMA) to determine the comparative efficacy, as measured by sustained virological response (SVR), between boceprevir (BOC), telaprevir (TEL), faldaprevir (FAL), simeprevir (SIM) and sofosbuvir (SOF) in combination with peginterferon-ribavirin (PR) against a control of PR.
DESIGN: A literature search was conducted to identify randomized controlled trials (RCTs) including adult patients with hepatitis C …
Authors
Druyts E; Lorenzi M; Toor K; Thorlund K; Mills EJ
Journal
QJM, Vol. 108, No. 4, pp. 299–306
Publisher
Oxford University Press (OUP)
Publication Date
4 2015
DOI
10.1093/qjmed/hcu202
ISSN
1460-2725