Journal article
Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat
Abstract
BACKGROUND: The role of transforming growth factor-beta 1 (TGF-β₁) in the onset of bone marrow fibrosis has been confirmed in some animal models. To further understand the genetic expression of some myeloproliferative disorders affecting marrow stem cells, however, it is necessary to develop a specific and reliable procedure to deliver modified adenoviral vectors into the bone marrow cavity. The aim of this paper is to report a surgical …
Authors
Rodriguez-Lecompte JC; Romero-Perez GA; Ramirez-Yañez G; Ask K; Gauldie J
Journal
European Surgical Research, Vol. 50, No. 3-4, pp. 282–291
Publisher
Karger Publishers
Publication Date
2013
DOI
10.1159/000351336
ISSN
0014-312X