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Multicentric Evaluation of a New PT Reagent Based...
Journal article

Multicentric Evaluation of a New PT Reagent Based on Recombinant Human Tissue Factor and Synthetic Phospholipids

Abstract

A new PT reagent based on recombinant human tissue factor and synthetic phospholipids (phosphatidyl choline and phosphatidyl serine) with defined fatty acid side chains was calibrated against BCT/253 and CRM 149R. A small but consistent bias in the International Sensitivity Index (ISI) value was obtained using either the human or rabbit brain reference material. ISI values were around 1.0 or slightly lower depending on the respective …

Authors

Bader R; Mannucci PMM; Tripodi A; Hirsh J; Keller F; Solleder EM; Hawkins P; Peng M; Pelzer H; Teijidor LM

Journal

Thrombosis and Haemostasis, Vol. 71, No. 03, pp. 292–299

Publisher

Thieme

Publication Date

1994

DOI

10.1055/s-0038-1642433

ISSN

0340-6245