Journal article
Synthesis and Processing of the Haemagglutinin—esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus
Abstract
The haemagglutinin-esterase gene (HE) of bovine coronavirus (BCV) encodes a major viral membrane glycoprotein that elicits BCV-neutralizing antibodies. The BCV HE gene was cloned into a human adenovirus serotype 5 (Ad5) transfer vector in place of early transcription region 3, and a helper-independent recombinant virus was constructed by rescue of the transcription unit by homologous in vivo recombination between the vector and Ad5 genomic DNA. …
Authors
Yoo D; Graham FL; Prevec L; Parker MD; Benkö M; Zamb T; Babiuk LA
Journal
Journal of General Virology, Vol. 73, No. 10, pp. 2591–2600
Publisher
Microbiology Society
Publication Date
October 1, 1992
DOI
10.1099/0022-1317-73-10-2591
ISSN
0022-1317
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdenoviridaeAdenovirus Early ProteinsAnimalsAntibody FormationCattleCells, CulturedCoronaviridaeDNA, RecombinantDNA, ViralGenetic VectorsGlycosylationHemagglutinins, ViralMembrane GlycoproteinsMiceProtein ConformationProtein Processing, Post-TranslationalRecombinant ProteinsTranscription, GeneticTransfectionViral Proteins