Transient Global Amnesia as the Presenting Feature of Heparin-Induced Thrombocytopenia Academic Article uri icon

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  • A 57-year-old man developed transient global amnesia within an hour of bolus unfractionated heparin administration on day 4 post-mitral valve replacement. Both immunoglobulin G-specific enzyme-linked immunosorbent assay and serotonin release assay were strongly positive for the antibodies that cause heparin-induced thrombocytopenia. The patient's cognitive functions returned to normal following discontinuation of unfractionated heparin and warfarin and commencement of lepirudin infusion.


  • Teh, Chun Huat
  • Robertson, Martyn N
  • Warkentin, Ted
  • Henriksen, Peter A
  • Brackenbury, Edward T
  • Anderson, Julia AM

publication date

  • May 2010