Journal article
Stability and sterility of recombinant tissue plasminogen activator at −30°C
Abstract
We assessed whether frozen recombinant tissue plasminogen activator (rt-PA) remains stable and sterile for up to 22 weeks at -30 degrees C. Our findings confirm that rt-PA is a cost-effective alternative to urokinase for restoring patency to occluded central venous catheters.
Authors
Wiernikowski JT; Crowther M; Clase CM; Ingram A; Andrew M; Chan AK
Journal
The Lancet, Vol. 355, No. 9222,
Publisher
Elsevier
Publication Date
6 2000
DOI
10.1016/s0140-6736(00)02411-9
ISSN
0140-6736