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Inhibition of antigen-induced secretion in the rat...
Journal article

Inhibition of antigen-induced secretion in the rat jejunum by interferon alpha/beta.

Abstract

Intestine from rats sensitized to egg albumin (EA) antigen responds to EA challenge with an increase in short-circuit current (Isc), indicative of predominantly chloride secretion. Here, we have examined the role of interferon alpha/beta (IFN alpha/beta) in the control of this event. Muscle-stripped jejunal segments from sensitized rats, mounted in Ussing chambers, displayed a reduced response to EA-challenge in the presence of IFN alpha/beta …

Authors

McKay DM; Bienenstock J; Perdue MH

Journal

Regional Immunology, Vol. 5, No. 1, pp. 53–59

Publication Date

1993

ISSN

0896-0623