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High efficacy of combined therapy with pegylated...
Journal article

High efficacy of combined therapy with pegylated interferon plus ribavirin in patients with hemophilia and chronic hepatitis C.

Abstract

BACKGROUND AND OBJECTIVES: Eradication of hepatitis C virus (HCV) is particularly difficult in patients with hemophilia. In this open, prospective, multicenter trial, the efficacy and tolerability of the combination therapy with pegylated interferon alpha2b (Peg-IFNalpha2b) plus ribavirin was evaluated in 64 human immunodeficiency virus (HIV) seronegative adult hemophiliacs with chronic hepatitis C naive to previous antiviral therapy. DESIGN …

Authors

Mancuso ME; Rumi MG; Santagostino E; Linari S; Coppola A; Mannucci PM; Colombo M

Journal

Haematologica, Vol. 91, No. 10, pp. 1367–1371

Publication Date

October 2006

ISSN

0390-6078