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Encapsulation of various recombinant mammalian...
Journal article

Encapsulation of various recombinant mammalian cell types in different alginate microcapsules

Abstract

Microencapsulation of recombinant "universal" cells with immunoprotective membranes is an alternate approach to somatic gene therapy. Therapeutic gene products secreted by these cells can be delivered to different patients without immunosuppression or genetic modification of the host's cells. The encapsulation of different mammalian cell types (epithelial cells, fibroblasts, and myoblasts) is compared among three alginate-based microcapsules: …

Authors

Peirone M; Ross CJD; Hortelano G; Brash JL; Chang PL

Journal

Journal of Biomedical Materials Research, Vol. 42, No. 4, pp. 587–596

Publisher

Wiley

Publication Date

December 15, 1998

DOI

10.1002/(sici)1097-4636(19981215)42:4<587::aid-jbm15>3.0.co;2-x

ISSN

0021-9304