Metabolic suppression identifies new antibacterial...

Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation

Abstract

Identification of antibacterials and then their mechanism of action using metabolic suppression profiling uncovers inhibitors targeting glycine metabolism, PABA and biotin biosynthesis.

Authors

Zlitni S; Ferruccio LF; Brown ED

Journal

Nature Chemical Biology, Vol. 9, No. 12, pp. 796–804

Publisher

Springer Nature

Publication Date

December 1, 2013

DOI

10.1038/nchembio.1361

ISSN

1552-4450

Associated Experts

Eric Brown

Professor, Faculty of Health Sciences

Visit profile

Labels