Journal article
Pharmacokinetics of plasma‐derived vs. recombinant FVIII concentrates: a comparative study
Abstract
Only very few pharmacokinetic (PK) studies comparing plasma derived FVIII (pd-FVIII) against recombinant FVIII (rFVIII) concentrates are available. The studies have been generally conducted to demonstrate the bioequivalence of a new product with an old one. The switch from a plasma-derived FVIII (pd-FVIII) to a rFVIII concentrate is a good moment to enrol the patients in a comparative PK study. To achieve information on the PK characteristics …
Authors
Morfini M; Marchesini E; Paladino E; Santoro C; Zanon E; Iorio A
Journal
Haemophilia, Vol. 21, No. 2, pp. 204–209
Publisher
Wiley
Publication Date
March 2015
DOI
10.1111/hae.12550
ISSN
1351-8216