Journal article
Comprehensive Canadian Review of the Off-Label Use of Recombinant Activated Factor VII in Cardiac Surgery
Abstract
BACKGROUND: This observational study sought to identify the off-label use pattern of recombinant activated factor VII (rFVIIa) in cardiac surgery and to identify predictors of its effectiveness and risk.
METHODS AND RESULTS: At 18 Canadian centers, 522 nonhemophiliac cardiac surgical patients received rFVIIa during the period 2003 through 2006; data were available, and retrospectively collected, on 503 patients. The median (quartile 1, quartile …
Authors
Karkouti K; Beattie WS; Arellano R; Aye T; Bussieres JS; Callum JL; Cheng D; Heinrich L; Kent B; Lee TWR
Journal
Circulation, Vol. 118, No. 4, pp. 331–338
Publisher
Wolters Kluwer
Publication Date
July 22, 2008
DOI
10.1161/circulationaha.108.764308
ISSN
0009-7322