Journal article
Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis
Abstract
BACKGROUND: The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment with anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical thrombolysis") rapidly removes thrombus and is hypothesized to reduce the risk of the post-thrombotic syndrome.
METHODS: We randomly assigned 692 patients with acute proximal deep-vein thrombosis to receive either …
Authors
Vedantham S; Goldhaber SZ; Julian JA; Kahn SR; Jaff MR; Cohen DJ; Magnuson E; Razavi MK; Comerota AJ; Gornik HL
Journal
The New England Journal of Medicine, Vol. 377, No. 23, pp. 2240–2252
Publisher
Massachusetts Medical Society
Publication Date
December 7, 2017
DOI
10.1056/nejmoa1615066
ISSN
0028-4793