Journal article
Interleukin 1β-induced increase in substance P in rat myenteric plexus
Abstract
BACKGROUND: Substance P (SP) is increased in the inflamed intestine of Trichinella spiralis-infected rats, but the underlying mechanism is unknown. Interleukin 1 beta (IL-1 beta) messenger RNA and protein is expressed in the longitudinal muscle-myenteric plexus (LM-MP) of this model. Thus, the purpose of the study was to examine the ability of human recombinant IL-1 beta (hrIL-1 beta) to increase SP in LM-MP preparations from the intestine of …
Authors
Hurst SM; Stanisz AM; Sharkey KA; Collins SM
Journal
Gastroenterology, Vol. 105, No. 6, pp. 1754–1760
Publisher
Elsevier
Publication Date
December 1993
DOI
10.1016/0016-5085(93)91073-q
ISSN
0016-5085