Journal article
Synergism between interleukins 1β and 6 on noradrenergic nerves in rat myenteric plexus
Abstract
BACKGROUND/AIMS: Because levels of interleukins 1 beta and 6 (IL-1 beta and IL-6) are elevated during intestinal Trichinella spiralis infection, they may mediate the changes in enteric neural function in that model. IL-1 beta suppresses norepinephrine release from the myenteric plexus, but the effect of IL-6 is unknown. Therefore, we investigated the effects of IL-6 alone and in combination with IL-1 beta on norepinephrine release.
METHODS: …
Authors
Rühl A; Hurst S; Collins SM
Journal
Gastroenterology, Vol. 107, No. 4, pp. 993–1001
Publisher
Elsevier
Publication Date
October 1994
DOI
10.1016/0016-5085(94)90223-2
ISSN
0016-5085