Journal article
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy
Abstract
Importance: Previous research suggested that soluble human recombinant thrombomodulin may reduce mortality among patients with sepsis-associated coagulopathy.
Objective: To determine the effect of human recombinant thrombomodulin vs placebo on 28-day all-cause mortality among patients with sepsis-associated coagulopathy.
Authors
Vincent J-L; Francois B; Zabolotskikh I; Daga MK; Lascarrou J-B; Kirov MY; Pettilä V; Wittebole X; Meziani F; Mercier E
Journal
JAMA: The Journal of the American Medical Association, Vol. 321, No. 20, pp. 1993–2002
Publisher
American Medical Association (AMA)
Publication Date
May 28, 2019
DOI
10.1001/jama.2019.5358
ISSN
0098-7484