Research Design Concept

subject area of

• 'Functional status of extremely preterm infants at kindergarten entry'.  Journal Articles
• 21st Century Evidence: Randomized Controlled Trials Versus Systematic Reviews and Meta-Analyses  Journal Articles
• 3D Ultrasound Measurement of Change in Carotid Plaque Volume  Journal Articles
• North American Vasovagal Pacemaker Study: Study Design and Organization  Journal Articles
• Curved versusStraight Stem UncementedTotal Hip ArthroplastyOsteoarthritisMulticenter trial (CUSTOM): design of a prospective blinded randomised controlled multicentre trial  Journal Articles
• Helicobacter pylori Eradication Therapy for Nonulcer Dyspepsia  Journal Articles
• Nash-wo-Numa(childhood growth & development) study protocol: factors that impact linear growth in children 9 to 15 years of age in Matiari, Pakistan  Journal Articles
• n-of-1 Randomized Controlled Trials: An Opportunity for Complementary and Alternative Medicine Evaluation  Journal Articles
• A Bayesian adaptive design for clinical trials of rare efficacy outcomes with multiple definitions  Journal Articles
• A CONTROLLED PROSPECTIVE STUDY OF THE EFFECT OF ENDURANCE TRAINING ON THE RECURRENCE RATE OF MYOCARDIAL INFARCTION  Journal Articles
• A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial  Journal Articles
• A Checklist for Reporting Valuation Studies of Multi-Attribute Utility-Based Instruments (CREATE)  Journal Articles
• A Comparison of Methods for Capturing Patient Preferences for Delivery of Mental Health Services to Low-Income Hispanics Engaged in Primary Care  Journal Articles
• A Consumer's Guide to Subgroup Analyses  Journal Articles
• A Controlled Trial of Teaching Critical Appraisal of the Clinical Literature to Medical Students  Journal Articles
• A Critical Analysis of Studies of State Drug Reimbursement Policies: Research in Need of Discipline  Journal Articles
• A Guide to Implementation Science for Phase 3 Clinical Trialists: Designing Trials for Evidence Uptake.  Journal Articles
• A Meta-Analytic Review of the Effect of Exercise on Smoking Cessation  Journal Articles
• A Method for Identifying Research Priorities for Health Systems Research on Health and Aging  Journal Articles
• A New Class of Robust Two-Sample Wald-Type Tests  Journal Articles
• A Pilot Feasibility Study of an Extension of the Acquaintanceship Recruitment Procedure in Recent-Onset Psychosis  Journal Articles
• A Practical Guide to Research: Design, Execution, and Publication  Journal Articles
• A Process for Systematically Reviewing the Literature: Providing the Research Evidence for Public Health Nursing Interventions  Journal Articles
• A Proposed Framework for Rigor and Transparency in Dysphagia Research: Prologue  Journal Articles
• A Prospective Comparison of Four Study Designs Used in Assessing Safety and Effectiveness of Drug Therapy in Hypertension Management  Journal Articles
• A Quality Analysis of Systematic Reviews in Dentistry, Part 1: Meta-Analyses of Randomized Controlled Trials  Journal Articles
• A Review and Analysis of Placebo Treatments, Placebo Effects, and Placebo Controls in Trials of Medical Procedures When Sham Is Not Inert  Journal Articles
• A Scoping Review of Personal, Financial, and Environmental Determinants of Mobility Among Older Adults  Journal Articles
• A Scoring Algorithm for Deriving Utility Values from the Neuro-QoL for Patients with Multiple Sclerosis  Journal Articles
• A Stimulated Recall Method for the Improved Assessment of Quantity and Quality of Social Media Use  Journal Articles
• A Systematic Review of Heparin to Treat Burn Injury  Journal Articles
• A Systematic Review of Interventions for Elder Abuse  Journal Articles
• A Systematic Review of the Quality of Trials Evaluating Biomedical HIV Prevention Interventions Shows That Many Lack Power  Journal Articles
• A Systematic Review of the Relationship Between Breastfeeding and Early Childhood Caries  Journal Articles
• A brief step-by-step guide on conducting a systematic review and meta-analysis of prognostic model studies  Journal Articles
• A brief transdiagnostic psychological intervention for Afghan asylum seekers and refugees in Austria: a randomized controlled trial  Journal Articles
• A call for consensus in defining efficacy in clinical trials for opioid addiction: combined results from a systematic review and qualitative study in patients receiving pharmacological assisted therapy for opioid use disorder  Journal Articles
• A clinician's guide to the assessment and interpretation of noninferiority trials for novel therapies.  Journal Articles
• A cluster randomized controlled trial for the Evaluation of routinely Measured PATient reported outcomes in HemodialYsis care (EMPATHY): a study protocol  Journal Articles
• A comment on Burgomaster et al. and a general plea to consider behavioral influences in human physiology studies  Journal Articles
• A comparison of a new multinomial stopping rule with stopping rules of fleming and gehan in single arm phase II cancer clinical trials  Journal Articles
• A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN)  Journal Articles
• A comparison of meta-analytic methods for synthesizing evidence from explanatory and pragmatic trials  Journal Articles
• A critical appraisal of bleeding events reported in venous thromboembolism prevention trials of patients undergoing hip and knee arthroplasty  Journal Articles
• A critical review of the relationship between impaired fibrinolysis and myocardial infarction  Journal Articles
• A double-blind, randomized controlled trial to compare the effect of biannual peripheral magnetic resonance imaging, radiography and standard of care disease progression monitoring on pharmacotherapeutic escalation in rheumatoid and undifferentiated inflammatory arthritis: study protocol for a randomized controlled trial  Journal Articles
• A framework of operating models for interdisciplinary research programs in clinical service organizations  Journal Articles
• A guidance was developed to identify participants with missing outcome data in randomized controlled trials  Journal Articles
• A guide and pragmatic considerations for applying GRADE to network meta-analysis  Journal Articles
• A guide for the performance of the Chinese hamster ovary cell/hypoxanthine-guanine phosphoribosyl transferase gene mutation assay  Journal Articles
• A guide to appropriately planning and conducting meta-analyses—Part 1: indications, assumptions and understanding risk of bias  Journal Articles
• A guide to evaluating survey research methodology in pediatric urology  Journal Articles
• A guide to interpreting discordant systematic reviews.  Journal Articles
• A life needs model of pediatric service delivery: services to support community participation and quality of life for children and youth with disabilities.  Journal Articles
• A longitudinal cohort study of symptoms and other concerns among Nigerian people with stages 3–5 chronic kidney diseases: study protocol  Journal Articles
• A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials  Journal Articles
• A method was developed for correcting the bias in the usual study weights in meta-analyses: author’s reply  Journal Articles
• A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol (vol 2, 113, 2013)  Journal Articles
• A minimum data set-Core outcome set, core data elements, and core measurement set-For degenerative cervical myelopathy research (AO Spine RECODE DCM): A consensus study.  Journal Articles
• A mixed methods evaluation of the maternal-newborn dashboard in Ontario: dashboard attributes, contextual factors, and facilitators and barriers to use: a study protocol  Journal Articles
• A modified Delphi and cross-sectional survey to facilitate selection of optimal outcomes and measures for a systematic review on geriatrician-led care models  Journal Articles
• A multi-centre clinical evaluation of isoflurane  Journal Articles
• A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry  Journal Articles
• A new 'Mechanistic-Practical” Framework for designing and interpreting randomized trials  Journal Articles
• A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials  Journal Articles
• A novel training simulator for portable ultrasound identification of incorrect newborn endotracheal tube placement – observational diagnostic accuracy study protocol  Journal Articles
• A patient decision aid for antidepressant use in pregnancy: study protocol for a randomized controlled trial  Journal Articles
• A phase II multi-institutional study assessing simultaneous in-field boost helical tomotherapy for 1-3 brain metastases  Journal Articles
• A picture is worth a thousand words: maps of HIV indicators to inform research, programs, and policy from NA‐ACCORD and CCASAnet clinical cohorts  Journal Articles
• A practical approach to evidence-based dentistry  Journal Articles
• A practical methodology for disaggregating the drivers of drug costs using administrative data  Journal Articles
• A practitioner's guide to developing critical appraisal skills  Journal Articles
• A prospective evaluation of edoxaban compared to warfarin in subjects undergoing cardioversion of atrial fibrillation: The EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study  Journal Articles
• A prospective multiple case study of the impact of emerging scientific evidence on established colorectal cancer screening programs: a study protocol  Journal Articles
• A prospective, double-blind, randomized, controlled clinical trial comparing standard wound care with adjunctive hyperbaric oxygen therapy (HBOT) to standard wound care only for the treatment of chronic, non-healing ulcers of the lower limb in patients with diabetes mellitus: a study protocol  Journal Articles
• A protocol for a Canadian prospective observational study of decision-making on active surveillance or surgery for low-risk papillary thyroid cancer  Journal Articles
• A protocol for a pragmatic randomized controlled trial using the Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY) platform approach to promote person-focused primary healthcare for older adults  Journal Articles
• A protocol for a scoping review of equity measurement in mental health care for children and youth  Journal Articles
• A protocol for a systematic review on the impact of unpublished studies and studies published in the gray literature in meta-analyses  Journal Articles
• A protocol for developing early warning score models from vital signs data in hospitals using ensembles of decision trees  Journal Articles
• A quantitative analysis of qualitative studies in clinical journals for the 2000 publishing year  Journal Articles
• A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects  Journal Articles
• A realist review to understand the efficacy and outcomes of interventions designed to minimise, reverse or prevent the progression of frailty  Journal Articles
• A reporting guideline for clinical platelet transfusion studies from the BEST Collaborative  Journal Articles
• A review of potential methods of determining critical effect size for designing environmental monitoring programs  Journal Articles
• A review of randomized controlled trials comparing the effectiveness of hand held computers with paper methods for data collection  Journal Articles
• A risk of bias instrument for non-randomized studies of exposures: A users’ guide to its application in the context of GRADE  Journal Articles
• A scoping review establishes need for consensus guidance on reporting health equity in observational studies  Journal Articles
• A scoping review of comparisons between abstracts and full reports in primary biomedical research  Journal Articles
• A small p-value from an observed data is not evidence of adequate power for future similar-sized studies: A cautionary note  Journal Articles
• A statistical note on Karl Pearson’s 1904 meta-analysis  Journal Articles
• A study of implementation factors for a novel approach to clinical trials: constructs for consideration in the coordination of direct-to-patient online-based medical research.  Journal Articles
• A suicide prevention strategy for youth presenting to the emergency department with suicide related behaviour: protocol for a randomized controlled trial  Journal Articles
• A survey to determine the zone of equipoise for the Proximal FEmur Resection or Internal Fixation fOR Metastases (PERFORM) randomized controlled trial.  Journal Articles
• A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations.  Journal Articles
• A systematic overview of adolescent suicide prevention programs.  Journal Articles
• A systematic overview of the effectiveness of home visiting as a delivery strategy for public health nursing interventions.  Journal Articles
• A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications  Journal Articles
• A systematic review of comparisons between protocols or registrations and full reports in primary biomedical research  Journal Articles
• A systematic review of definitions and reporting of bleeding outcome measures in haemophilia  Journal Articles
• A systematic review of psychoeducational intervention trials for the management of chronic stable angina  Journal Articles
• A systematic review of psychometric evaluations of outcome assessments for complex regional pain syndrome  Journal Articles
• A systematic review of quality of reporting in registered intimate partner violence studies: where can we improve?  Journal Articles
• A systematic review of screening questionnaires for obstructive sleep apnea  Journal Articles
• A systematic review of the quality of publications reporting coronary artery bypass grafting trials.  Journal Articles
• A systematic survey of randomised trials that stopped early for reasons of futility  Journal Articles
• A systematic survey of the methods literature on the reporting quality and optimal methods of handling participants with missing outcome data for continuous outcomes in randomized controlled trials  Journal Articles
• A systematic survey on reporting and methods for handling missing participant data for continuous outcomes in randomized controlled trials  Journal Articles
• A systematic survey showed important limitations in the methods for assessing drug safety among systematic reviews  Journal Articles
• A systematic survey shows that reporting and handling of missing outcome data in networks of interventions is poor  Journal Articles
• A tailored online safety and health intervention for women experiencing intimate partner violence: the iCAN Plan 4 Safety randomized controlled trial protocol  Journal Articles
• A taxonomy and critical review of tested strategies for the application of clinical practice recommendations: from "official" to "individual" clinical policy.  Journal Articles
• A taxonomy and framework for identifying and developing actionable statements in guidelines suggests avoiding informal recommendations  Journal Articles
• A three-stage approach to measuring health inequalities and inequities  Journal Articles
• A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial  Journal Articles
• A tutorial on methodological studies: the what, when, how and why  Journal Articles
• A tutorial on pilot studies: the what, why and how  Journal Articles
• A tutorial on sensitivity analyses in clinical trials: the what, why, when and how  Journal Articles
• ACCOUNTING FOR BETWEEN‐STUDY VARIATION IN INCREMENTAL NET BENEFIT IN VALUE OF INFORMATION METHODOLOGY  Journal Articles
• AHRQ Series Paper 4: Assessing harms when comparing medical interventions: AHRQ and the Effective Health-Care Program  Journal Articles
• ALeS: adaptive-length spaced-seed design  Journal Articles
• APPLICATION OF THE CONSOLIDATED STANDARDS OF REPORTING TRIALS (CONSORT) IN THE FRACTURE CARE LITERATURE  Journal Articles
• Above all, do no harm: Assessing the risk of an adverse reaction  Journal Articles
• Academic Primer Series: Five Key Papers about Study Designs in Medical Education  Journal Articles
• Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE)  Journal Articles
• Accounting for center in the Early External Cephalic Version trials: an empirical comparison of statistical methods to adjust for center in a multicenter trial with binary outcomes  Journal Articles
• Accounting for center-level effects in multicenter randomized controlled trials  Journal Articles
• Accounting for health literacy and intervention preferences when reducing unhealthy snacking: protocol for an online randomised controlled trial  Journal Articles
• Accuracy and reliability of 'specialized' physical therapists in auscultating tape-recorded lung sounds.  Journal Articles
• Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods  Journal Articles
• Active patient involvement in the education of health professionals  Journal Articles
• Acupuncture for enhancing early recovery of bowel function in cancer  Journal Articles
• Acupuncture for the alleviation of lateral epicondyle pain: a systematic review  Journal Articles
• Acute Cardiac Functional and Morphological Changes After Anthracycline Infusions in Children  Journal Articles
• Adaptive clinical trials in surgery: A scoping review of methodological and reporting quality  Journal Articles
• Adaptive design methods in dialysis clinical trials: a systematic review protocol  Journal Articles
• Addressing Challenges When Applying GRADE to Public Health Guidelines: A Scoping Review Protocol and Pilot Analysis  Journal Articles
• Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers  Journal Articles
• Addressing efficiency: Economic evaluation and the agenda for CAM researchers  Journal Articles
• Addressing the Unit of Analysis in Medical Care Studies  Journal Articles
• Addressing the burden of hospital‐related venous thromboembolism: the role of extended anticoagulant prophylaxis  Journal Articles
• Addressing uncertainty in relative effectiveness assessments by HTA organizations  Journal Articles
• Adherence measurement and patient recruitment methods are poor in intervention trials to improve patient adherence  Journal Articles
• Adherence to Standards for Reporting Diagnostic Accuracy in Emergency Medicine Research  Journal Articles
• Adjuvant chemotherapy with CEF versus CMF for node-positive breast cancer.  Journal Articles
• Adolescents with cerebral palsy: stability in measurement of quality of life and health‐related quality of life over 1 year  Journal Articles
• Adopting, implementing and assimilating coproduced health and social care innovations involving structurally vulnerable populations: findings from a longitudinal, multiple case study design in Canada, Scotland and Sweden  Journal Articles
• Advanced practice nursing in Europe—Results from a pan‐European survey of 35 countries  Journal Articles
• Advanced statistics: Understanding Medical Record Review (MRR) Studies  Journal Articles
• Advances in Genomic Analysis of Stroke  Journal Articles
• Advancing Concussion Assessment in Pediatrics (A-CAP): a prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: study protocol  Journal Articles
• Advancing implementation frameworks with a mixed methods case study in child behavioral health  Journal Articles
• Advancing the Science in Gastric Pre-Neoplasia: Study Design Considerations  Journal Articles
• Affective Instability in Personality Disorders  Journal Articles
• Age trends in direct medical costs of pediatric asthma: A population study  Journal Articles
• Age-Specific Search Strategies for Medline  Journal Articles
• Age-related changes in GABA and benzodiazepine receptor binding in rat brain are influenced by sampling time  Journal Articles
• Agreement between study designs: a systematic review comparing observational studies and randomized trials of surgical treatments for necrotizing enterocolitis  Journal Articles
• Agreement in reporting between trial publications and current clinical trial registry in high impact journals: A methodological review  Journal Articles
• Algorithm for predicting death among older adults in the home care setting: study protocol for the Risk Evaluation for Support: Predictions for Elder-life in the Community Tool (RESPECT)  Journal Articles
• All-arthroscopic versus mini-open repair of small or moderate-sized rotator cuff tears: A protocol for a randomized trial [NCT00128076]  Journal Articles
• Allocation techniques for balance at baseline in cluster randomized trials: a methodological review  Journal Articles
• Alternatives to project-specific consent for access to personal information for health research: Canadian public opinion  Conferences
• Alternatives to project-specific consent for access to personal information for health research: Insights from a public dialogue  Journal Articles
• Although not consistently superior, the absolute approach to framing the minimally important difference has advantages over the relative approach  Journal Articles
• An Assessment of Clinically Useful Measures of the Consequences of Treatment  Journal Articles
• An Ep-ICD Based Index Is a Marker of Aggressiveness and Poor Prognosis in Thyroid Carcinoma  Journal Articles
• An Indigenous Lens on Priorities for the Canadian Brain Research Strategy  Journal Articles
• An Introduction to Evidence-Based Practice for Hand Surgeons and Therapists  Journal Articles
• An N of 1 Service: Applying the Scientific Method in Clinical Practice  Journal Articles
• An Official ATS Statement: Grading the Quality of Evidence and Strength of Recommendations in ATS Guidelines and Recommendations  Journal Articles
• An empirical comparison of methods for analyzing correlated data from a discrete choice survey to elicit patient preference for colorectal cancer screening  Journal Articles
• An empirical study using permutation-based resampling in meta-regression  Journal Articles
• An evaluation of the comparative effectiveness of geriatrician-led comprehensive geriatric assessment for improving patient and healthcare system outcomes for older adults: a protocol for a systematic review and network meta-analysis  Journal Articles
• An evaluation of the structural validity of the shoulder pain and disability index (SPADI) using the Rasch model  Journal Articles
• An evidence-based approach to gastroenterology therapy  Journal Articles
• An exploratory cluster randomised controlled trial of knowledge translation strategies to support evidence-informed decision-making in local governments (The KT4LG study)  Journal Articles
• An improved method for analysis of interrupted time series (ITS) data: accounting for patient heterogeneity using weighted analysis  Journal Articles
• An institutional ethnography of chronic pain management in family medicine (COPE) study protocol  Journal Articles
• An integrated exploration into the social and environmental determinants of health: the Saskatchewan Population Health and Evaluation Research Unit (SPHERU).  Journal Articles
• An introduction to multiplicity issues in clinical trials: the what, why, when and how  Journal Articles
• An overview of platform trials with a checklist for clinical readers  Journal Articles
• Analysis and Interpretation of Treatment Effects in Subgroups of Patients in Randomized Clinical Trials  Journal Articles
• Analysis and reporting of stratified cluster randomized trials—a systematic survey  Journal Articles
• Analysis of Observational Studies: A Guide to Understanding Statistical Methods  Journal Articles
• Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. Reply.  Journal Articles
• Anticoagulant therapy for the thrombotic complications of the antiphospholipid antibody syndrome  Conferences
• Anticonvulsants for behavioral and psychological symptoms in dementia: protocol for a systematic review  Journal Articles
• Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung, and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland.  Journal Articles
• Análisis interino en ensayos clínicos: una guía metodológica  Journal Articles
• Applicability of the AGREE II Instrument in Evaluating the Development Process and Quality of Current National Academy of Clinical Biochemistry Guidelines  Journal Articles
• Application of Epidemiological Methodology to Sports ana Exercise Science Research  Journal Articles
• Application of the STROBE statement to the hypospadias literature: Report of the international pediatric urology task force on hypospadias  Journal Articles
• Applications of wearable sensors in upper extremity MSK conditions: a scoping review  Journal Articles
• Applying epidemiological principles to ergonomics: A checklist for incorporating sound design and interpretation of studies  Journal Articles
• Applying evidence-based methods to the development and use of adverse outcome pathways  Journal Articles
• Appraisal of clinical practice guidelines for management of paediatric type 2 diabetes mellitus using the AGREE II instrument: a systematic review protocol  Journal Articles
• Appraising Qualitative Research for Evidence Syntheses: A Compendium of Quality Appraisal Tools  Journal Articles
• Appraising the exercise oncology literature: a reminder of the rigour needed in systematic reviews  Journal Articles
• Approaches of integrating the development of guidelines and quality indicators: a systematic review  Journal Articles
• Archimedes: does caffeine treatment for apnoea of prematurity improve neurodevelopmental outcome in later life?  Journal Articles
• Are We Measuring What Really Counts?  Journal Articles
• Are current standards of reporting quality for clinical trials sufficient in addressing important sources of bias?  Journal Articles
• Are placebo‐controlled trials ethical in areas where current guidelines recommend therapy? No  Journal Articles
• Are postbereavement research interviews distressing to carers? Lessons learned from palliative care research  Journal Articles
• Are systematic reviews and meta-analyses still useful research? Yes  Journal Articles
• Are the Results of the Extracranial–Intracranial Bypass Trial Generalizable?  Journal Articles
• Are the correct outcomes being measured in studies of oral anticoagulants? A systematic survey  Journal Articles
• As a matter of fact: evidence-based decision-making unplugged  Journal Articles
• Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial  Journal Articles
• Assessing exertional dyspnea in patients with idiopathic pulmonary fibrosis  Journal Articles
• Assessing fragility of statistically significant findings from randomized controlled trials assessing pharmacological therapies for opioid use disorders: a systematic review  Journal Articles
• Assessing proximal risks for acute traumatic events: the case-crossover design  Journal Articles
• Assessing sensitivity to change: choosing the appropriate change coefficient  Journal Articles
• Assessing the Implementation and Effectiveness of the Electronic Patient-Reported Outcome Tool for Older Adults With Complex Care Needs: Mixed Methods Study  Journal Articles
• Assessing the effectiveness of ‘pulse radiofrequency treatment of dorsal root ganglion’ in patients with chronic lumbar radicular pain: study protocol for a randomized control trial  Journal Articles
• Assessing the quality of reports of randomised trials: implications for the conduct of meta-analyses.  Journal Articles
• Assessment of Evidence Quality in Inflammatory Bowel Disease Guidance: The Use and Misuse of GRADE  Journal Articles
• Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how  Journal Articles
• Assessment of clinically relevant bleeding as a surrogate outcome for major bleeding: validation by meta‐analysis of randomized controlled trials  Journal Articles
• Assessment of effectiveness of major bleeding management: proposed definitions for effective hemostasis: communication from the SSC of the ISTH  Journal Articles
• Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol  Journal Articles
• Assistive technologies that support social interaction in long-term care homes  Journal Articles
• Assistive technologies that support social interaction in long-term care homes: a scoping review protocol.  Journal Articles
• Association between BDNF levels and suicidal behaviour: a systematic review protocol  Journal Articles
• Association between body mass index and suicidal behaviors: a systematic review protocol  Journal Articles
• Association between cannabis use and treatment outcomes in patients receiving methadone maintenance treatment: a systematic review protocol  Journal Articles
• Association between framing of the research question using the PICOT format and reporting quality of randomized controlled trials  Journal Articles
• Association between mesothelin expression and survival outcomes in patients with triple-negative breast cancer: a protocol for a systematic review  Journal Articles
• Association between progression-free survival and health-related quality of life in oncology: a systematic review protocol  Journal Articles
• Association between statistical significance and time to publication among systematic reviews: a study protocol for a meta-epidemiological investigation  Journal Articles
• Association between vaping and health outcomes in patients with opioid use disorder: a systematic review protocol  Journal Articles
• Assumptions of Expected Benefits in Randomized Phase III Trials Evaluating Systemic Treatments for Cancer  Journal Articles
• Attending to Striatal Ups and Downs in Addictions  Journal Articles
• Attributes of context relevant to healthcare professionals’ use of research evidence in clinical practice: a multi-study analysis  Journal Articles
• Audience responses to a research‐based drama about life after breast cancer  Journal Articles
• Author guidelines for conducting systematic reviews and meta-analyses  Journal Articles
• Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts  Journal Articles
• Authorship and Ethical Considerations in the Conduct of Observational Studies  Journal Articles
• Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial  Journal Articles
• Balancing risk and benefit in venous thromboembolism trials: concept for a bivariate endpoint trial design and analytic approach  Journal Articles
• Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial  Journal Articles
• Barriers to HIV care among Francophone African, Caribbean and Black immigrant people living with HIV in Canada: a protocol for a scoping systematic review  Journal Articles
• Barriers to participating in an HIV vaccine trial  Journal Articles
• Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic  Journal Articles
• Basic epidemiology research designs I: cross-sectional design  Journal Articles
• Bayesian methods for pilot studies  Journal Articles
• Be careful about drawing conclusions.  Journal Articles
• Bedtime versus morning use of antihypertensives for cardiovascular risk reduction (BedMed): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial  Journal Articles
• Before–after paired data  Journal Articles
• Bench-to-bedside research and the human tumor stem-cell assay--bridging the credibility gap.  Journal Articles
• Benchmarking: Applications to Transfusion Medicine  Journal Articles
• Benefit-risk ratios in the assessment of the clinical evidence of a new therapy  Journal Articles
• Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature  Journal Articles
• Best (but oft-forgotten) practices: sensitivity analyses in randomized controlled trials  Journal Articles
• Best (but oft-forgotten) practices: the multiple problems of multiplicity—whether and how to correct for many statistical tests  Journal Articles
• Best Practice for MRI Diagnostic Accuracy Research With Lessons and Examples from the LI‐RADS Individual Participant Data Group  Journal Articles
• Best Practices for BREAST-Q Research: A Systematic Review of Study Methodology  Journal Articles
• Best foot forward: now is the time for Canadian ethical guidance on prospective interventional trials of antemortem interventions in organ donation  Journal Articles
• Beyond the treatment effect: Evaluating the effects of patient preferences in randomised trials  Journal Articles
• Bias in transfusion research: from study design to result reporting  Journal Articles
• Bias-corrected estimator for intraclass correlation coefficient in the balanced one-way random effects model  Journal Articles
• Binary Outcomes Are Not Better than Continuous Variables in Randomized Controlled Trials  Journal Articles
• Biological plausibility in environmental health systematic reviews: a GRADE concept paper  Journal Articles
• Body-mass index, abdominal adiposity, and cardiovascular risk  Journal Articles
• Brazilian medicinal plants to treat upper respiratory tract and bronchial illness: systematic review and meta-analyses—study protocol  Journal Articles
• Bridge or continue Coumadin for device surgery: a randomized controlled trial rationale and design  Journal Articles
• Bringing health services research to (and from) critical care  Journal Articles
• Bringing the Family's Voice to Research  Journal Articles
• Bringing the Life Needs Model to life: implementing a service delivery model for pediatric rehabilitation.  Journal Articles
• Bronchodilator delivery in acute airflow obstruction. A meta-analysis  Journal Articles
• Building Bridges: Describing a Process for Indigenous Engagement in Epidemiology  Journal Articles
• Building clinical trial priorities at the University of Rwanda  Journal Articles
• CIHR Candrive Cohort Comparison with Canadian Household Population Holding Valid Driver’s Licenses  Journal Articles
• CNODES: the Canadian Network for Observational Drug Effect Studies.  Journal Articles
• CONCEPTT: Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial: A multi-center, multi-national, randomized controlled trial - Study protocol  Journal Articles
• CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials  Journal Articles
• CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials  Journal Articles
• CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (Chinese version)  Journal Articles
• CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomised trials  Journal Articles
• CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials  Journal Articles
• CONSORT and clinical trial reporting: room for improvement  Journal Articles
• CONSORT comes to TRANSFUSION  Journal Articles
• CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement  Journal Articles
• CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement  Journal Articles
• CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration  Journal Articles
• CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration  Journal Articles
• COST AND EFFICIENCY IN THE CHOICE OF MATCHED AND UNMATCHED CASE-CONTROL STUDY DESIGNS1  Journal Articles
• COVID-19 clinical trials: learning from exceptions in the research chaos.  Journal Articles
• COVID-19 coronavirus research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine  Journal Articles
• CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients  Journal Articles
• Can We Learn Anything from Small Trials?  Journal Articles
• Can an antimicrobial stewardship program reduce length of stay of immune-competent adult patients admitted to hospital with diagnosis of community-acquired pneumonia? Study protocol for pragmatic controlled non-randomized clinical study  Journal Articles
• Can observational studies replace or complement experiment?  Journal Articles
• Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses?  Journal Articles
• Can we differentiate the low-molecular-weight heparins?  Journal Articles
• Canadian Alliance for Healthy Hearts and Minds: First Nations Cohort Study Rationale and Design  Journal Articles
• Canadian Amiodarone Myocardial Infarction Arrhythmia Trial (CAMIAT): Rationale and protocol  Journal Articles
• Canadian Phase III Randomized Trial of Stereotactic Body Radiotherapy Versus Conventionally Hypofractionated Radiotherapy for Stage I, Medically Inoperable Non–Small-Cell Lung Cancer – Rationale and Protocol Design for the Ontario Clinical Oncology Group (OCOG)-LUSTRE Trial  Journal Articles
• Canadian study of health and aging: study methods and prevalence of dementia.  Journal Articles
• Candesartan in heart failure—assessment of reduction in mortality and morbidity (CHARM): Rationale and design  Journal Articles
• Capture-mark-recapture to estimate the number of missed articles for systematic reviews in surgery  Journal Articles
• Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada  Journal Articles
• Cardiac rehabilitation after myocardial infarction. Combined experience of randomized clinical trials  Journal Articles
• Cardiovascular Thrombotic Events in Controlled, Clinical Trials of Rofecoxib  Journal Articles
• Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints  Journal Articles
• Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study  Journal Articles
• Case-control studies for the evaluation of screening  Journal Articles
• Celebrities’ impact on health-related knowledge, attitudes, behaviors, and status outcomes: protocol for a systematic review, meta-analysis, and meta-regression analysis  Journal Articles
• Central coordination as an alternative for local coordination in a multicenter randomized controlled trial: the FAITH trial experience  Journal Articles
• Central statistical monitoring: Detecting fraud in clinical trials  Journal Articles
• Central venous catheter replacement strategies  Journal Articles
• Challenges in Systematic Reviews That Evaluate Drug Efficacy or Effectiveness  Journal Articles
• Challenges in designing antirheumatic drug trials.  Journal Articles
• Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction  Journal Articles
• Challenges to complete and useful data sharing  Journal Articles
• Changing primary care capacity in Canada: protocol for a cross-provincial mixed methods study.  Journal Articles
• Chapter 5: Assessing Risk of Bias as a Domain of Quality in Medical Test Studies  Journal Articles
• Characteristics and quality of systematic reviews and meta-analyses of observational nutritional epidemiology: a cross-sectional study  Journal Articles
• Characteristics of creative individuals: An umbrella review protocol.  Journal Articles
• Characteristics of post hoc subgroup analyses of oncology clinical trials: a systematic review  Journal Articles
• Characteristics, Progression, and Output of Randomized Platform Trials  Journal Articles
• Characteristics, consent patterns, and challenges of randomized trials using the Trials within Cohorts (TwiCs) design - A scoping review  Journal Articles
• Checklist for studies of HIV drug resistance prevalence or incidence: rationale and recommended use  Journal Articles
• Chemotherapy for recurrent, metastatic, or persistent cervical cancer: a systematic review  Journal Articles
• Child hunger in Canada.  Journal Articles
• Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis  Journal Articles
• Chronic pain self-management support with pain science education and exercise (COMMENCE): study protocol for a randomized controlled trial  Journal Articles
• Climate change, biodiversity loss, and Indigenous Peoples’ health and wellbeing: a systematic umbrella review protocol  Journal Articles
• Clinical Commentary in Response To: Relationship between Patient Satisfaction and Functional Outcome Metrics 3 Months after Surgical Treatment for Distal Radius Fractures  Journal Articles
• Clinical Comparisons of Inhaler Systems: What are the Important Aspects?  Journal Articles
• Clinical Experience and Quality of Health Care  Journal Articles
• Clinical Presentation of Attention-Deficit/Hyperactivity Disorder in Preschool Children: The Preschoolers with Attention-Deficit/Hyperactivity Treatment Study (PATS)  Journal Articles
• Clinical Research Designs: Quantitative Studies  Journal Articles
• Clinical Research in Aesthetic Surgery  Journal Articles
• Clinical Research in Breast Surgery: Reduction and Postmastectomy Reconstruction  Journal Articles
• Clinical Research in Head and Neck Reconstruction  Journal Articles
• Clinical Research in Pediatric Plastic Surgery and Systematic Review of Quality-of-Life Questionnaires  Journal Articles
• Clinical Research on Acupuncture: Part 1. What Have Reviews of the Efficacy and Safety of Acupuncture Told Us So Far?  Journal Articles
• Clinical Research on Acupuncture: Part 2. Controlled Clinical Trials, an Overview of Their Methods  Journal Articles
• Clinical Research: From Case Reports to International Multicenter Clinical Trials  Journal Articles
• Clinical Trial Data Sharing for COVID-19–Related Research  Journal Articles
• Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium.  Journal Articles
• Clinical Trial Design in Acute Lung Injury—Issues and Controversies  Journal Articles
• Clinical Trial Design in Fracture-Healing Research: Meeting the Challenge  Journal Articles
• Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016  Journal Articles
• Clinical Trial Registration in Physical Therapy Journals: Recommendations from the International Society of Physiotherapy Journal Editors  Journal Articles
• Clinical Usefulness of n-of-1 Randomized Controlled Trials in Patients with Nonreversible Chronic Airflow Limitation  Journal Articles
• Clinical and Methodological Factors Related to Reliability of the Best-Estimate Diagnostic Procedure  Journal Articles
• Clinical case reports and case series research in evaluating surgery. Part II. The content and form: uses of single clinical case reports and case series research in surgical specialties.  Journal Articles
• Clinical diagnostic criteria for premenstrual syndrome and guidelines for their quantification for research studies  Journal Articles
• Clinical experience may affect clinician compliance with assigned treatment in randomized trials  Journal Articles
• Clinical impact versus factor analysis for quality of life questionnaire construction  Journal Articles
• Clinical markers of endometriosis: Have we been too quick to judge?  Journal Articles
• Clinical neurophysiology: Research methods and event-related potential components as assessment tools  Chapters
• Clinical practice guideline on the use of manipulation or mobilization in the treatment of adults with mechanical neck disorders  Journal Articles
• Clinical research design and reporting: always room for improvement!  Journal Articles
• Clinical trial design in metastatic breast cancer: a commentary.  Journal Articles
• Clinical trial registration in physiotherapy journals: Recommendations from the International Society of Physiotherapy Journal Editors  Journal Articles
• Clinical trials evaluating pathogen‐reduced platelet products: methodologic issues and recommendations  Journal Articles
• Clinical trials in COVID-19 management & prevention: A meta-epidemiological study examining methodological quality  Journal Articles
• Clinical trials of disease stages in COVID 19: complicated and often misinterpreted  Journal Articles
• Clinician trialist rounds: 28. When RCT participants are lost to follow-up. Part 1: Why even a few can matter  Journal Articles
• Clinician-trialist rounds: 11. When your grant gets turned down – part 1: remorse, anger, and reconciliation  Journal Articles
• Clinician-trialist rounds: 25. Designing an evidence-based introductory graduate course in clinical trials. Part 2: Applying the evidence to your RCT course design  Journal Articles
• Clonidine for sedation in the critically ill: a systematic review and meta-analysis (protocol)  Journal Articles
• Clopidogrel and percutaneous coronary intervention  Journal Articles
• Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication  Journal Articles
• Coenrollment in a Randomized Trial of High-Frequency Oscillation  Conferences
• Cohort Profile: The Canadian Observational Cohort collaboration  Journal Articles
• Cohort studies investigating the effects of exposures: key principles that impact the credibility of the results  Journal Articles
• Collaborative leadership and the implementation of community-based fall prevention initiatives: a multiple case study of public health practice within community groups  Journal Articles
• Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation  Journal Articles
• Colloid Use for Fluid Resuscitation: Evidence and Spin  Journal Articles
• Colloid Use in the Critically Ill  Journal Articles
• Comment on “Perspective: NutriGrade: A Scoring System to Assess and Judge the Meta-Evidence of Randomized Controlled Trials and Cohort Studies in Nutrition Research”  Journal Articles
• Commentary III - Making workplaces healthier: generating better evidence on work organization intervention research  Journal Articles
• Comments on ‘Sequential meta-analysis: an efficient decision-making tool’ by I van der Tweel and C Bollen  Journal Articles
• Common Pitfalls in the Conduct of Clinical Research  Journal Articles
• Common Sense Oncology principles for the design, analysis, and reporting of phase 3 randomised clinical trials.  Journal Articles
• Common data elements for clinical research in mitochondrial disease: a National Institute for Neurological Disorders and Stroke project  Journal Articles
• Communication Beliefs About Youth and Old Age in Asia and Canada  Journal Articles
• Community service provider perceptions of implementing older adult fall prevention in Ontario, Canada: a qualitative study  Journal Articles
• Comparative effectiveness of monotherapies and combination therapies for patients with hypertension: protocol for a systematic review with network meta-analyses  Journal Articles
• Comparing the diagnostic accuracy of five common tumour biomarkers and CA19-9 for pancreatic cancer: a protocol for a network meta-analysis of diagnostic test accuracy  Journal Articles
• Comparing the feasibility, acceptability, clinical-, and cost-effectiveness of mental health e-screening to paper-based screening on the detection of depression, anxiety, and psychosocial risk in pregnant women: a study protocol of a randomized, parallel-group, superiority trial  Journal Articles
• Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART  Journal Articles
• Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane review users: study protocol for a randomized controlled trial  Journal Articles
• Comparison of 12 Risk Stratification Schemes to Predict Stroke in Patients With Nonvalvular Atrial Fibrillation  Journal Articles
• Comparison of Echocardiographic and Cardiac Magnetic Resonance Imaging for Assessing Right Ventricular Function in Adults With Repaired Tetralogy of Fallot  Journal Articles
• Comparison of Preprint Postings of Randomized Clinical Trials on COVID-19 and Corresponding Published Journal Articles  Journal Articles
• Comparison of Standardization Methods for the Harmonization of Phenotype Data: An Application to Cognitive Measures  Journal Articles
• Comparison of health-related quality of life in patients with atrial fibrillation treated with catheter ablation or antiarrhythmic drug therapy: a systematic review and meta-analysis protocol  Journal Articles
• Comparison of physical interventions, behavioral interventions, natural health products, and pharmacologics to manage hot flashes in patients with breast or prostate cancer: protocol for a systematic review incorporating network meta-analyses  Journal Articles
• Comparison of questionnaires determining patient satisfaction with medical care.  Journal Articles
• Comparison of the ability of double‐robust estimators to correct bias in propensity score matching analysis. A Monte Carlo simulation study  Journal Articles
• Comparison of ventilatory modes to facilitate liberation from mechanical ventilation: protocol for a systematic review and network meta-analysis  Journal Articles
• Complementary medicine and older people: past research and future directions  Journal Articles
• Complexity science education for clinical nurse researchers  Journal Articles
• Complication Reporting in Orthopaedic Trials  Journal Articles
• Computerized administration of health-related quality of life instruments compared to interviewer administration may reduce sample size requirements in clinical research: a pilot randomized controlled trial among rheumatology patients.  Journal Articles
• Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies  Journal Articles
• Concurrent Cisplatin-based Chemotherapy plus Radiotherapy for Cervical Cancer:  Journal Articles
• Concurrent validity of the alcohol purchase task in relation to alcohol involvement: protocol for a systematic review and meta-analysis  Journal Articles
• Conducting EQ-5D Valuation Studies in Resource-Constrained Countries: The Potential Use of Shrinkage Estimators to Reduce Sample Size  Journal Articles
• Conducting economic evaluations alongside multinational clinical trials: Toward a research consensus  Journal Articles
• Conducting industry-partnered trials in orthopaedic surgery  Journal Articles
• Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence  Journal Articles
• Confidence interval of risk difference by different statistical methods and its impact on the study conclusion in antibiotic non-inferiority trials  Journal Articles
• Confidentiality and prescriptions.  Journal Articles
• Confounding: What is it and how do we deal with it?  Journal Articles
• Confronting the Confounders: The Meaning, Detection, and Treatment of Confounders in Research  Journal Articles
• Consensus statement on the methodology of injury and illness surveillance in FINA (aquatic sports)  Journal Articles
• Consent for use of personal information for health research: Do people with potentially stigmatizing health conditions and the general public differ in their opinions?  Journal Articles
• Considerations and guidance in designing equity-relevant clinical trials  Journal Articles
• Considerations when designing, analyzing, and reporting reliability studies.  Journal Articles
• Considering race/ethnicity and socio-economic status in randomized controlled trials. A commentary on Frampton et al.'s systematic review generalizing trial findings and tackling health disparities in asthma research  Journal Articles
• Consistency of Phase III Clinical Trial Abstracts Presented at an Annual Meeting of the American Society of Clinical Oncology Compared With Their Subsequent Full-Text Publications  Conferences
• Consolidation Therapy With Autologous Bone Marrow Transplantation in Adults With Acute Myeloid Leukemia: A Meta-analysis  Journal Articles
• Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials  Journal Articles
• Construction of social value or utility-based health indices: The usefulness of factorial experimental design plans  Journal Articles
• Contemporary trends in the level of evidence in general thoracic surgery clinical research  Journal Articles
• Content and methods of studies on the prevention and treatment of mental disorders in selected psychiatric journals.  Journal Articles
• Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project  Journal Articles
• Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals  Journal Articles
• Controversy and Debate Series on Core Outcome Sets: The SOLAR (Standardized Outcomes Linking Across StakeholdeRs) system and hub and spokes model for direct core outcome measures in health care and its relation to GRADE  Journal Articles
• Coproduction in Social Prescribing Initiatives: Protocol for a Scoping Review.  Journal Articles
• Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery  Journal Articles
• Core Outcome Set Development for Adolescent Major Depressive Disorder Clinical Trials: A Registered Report  Journal Articles
• Core Outcome Set for IgE‐mediated food allergy clinical trials and observational studies of interventions: International Delphi consensus study ‘COMFA’  Journal Articles
• Core Outcomes Set for Trials in People With Coronavirus Disease 2019  Journal Articles
• Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study “PC-COS Children”  Journal Articles
• Core outcome set for studies on pregnant women with vasa previa (COVasP): a study protocol  Journal Articles
• Coronary stent assessability by 64 slice multi‐detector computed tomography  Journal Articles
• Correction for Multiple Testing  Journal Articles
• Correction to the Relative Risk Calculation for Gadolinium-enhanced MR Imaging and Nephrogenic Systemic Fibrosis  Journal Articles
• Correlation of single arm versus randomised phase 2 oncology trial characteristics with phase 3 outcome  Journal Articles
• Correspondence  Journal Articles
• Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial  Journal Articles
• Corticosteroid treatment for sepsis  Journal Articles
• Corticosteroids in sepsis: an updated systematic review and meta-analysis (protocol)  Journal Articles
• Cost Implication of an Early Invasive Strategy on Weekdays and Weekends in Patients With Acute Coronary Syndromes  Journal Articles
• Costs and Cost-Effectiveness of Allogeneic Stem Cell Transplantation in Children Are Predictable  Journal Articles
• Counting the cost of proton pump inhibitors  Journal Articles
• Credibility of claims of subgroup effects in randomised controlled trials: systematic review  Journal Articles
• Critical Appraisal of Research Evidence for Its Validity and Usefulness  Journal Articles
• Critical Care Cardiology Research  Journal Articles
• Critical appraisal of rigour in interpretive phenomenological nursing research  Journal Articles
• Critical appraisal of the health research literature: prevalence or incidence of a health problem.  Journal Articles
• Critical appraisal of the orthopaedic literature: Therapeutic and economic analysis  Journal Articles
• Critical reflections on evidence, ethics and effectiveness in the management of tuberculosis: public health and global perspectives.  Journal Articles
• Cross-linkedversusconventional polyethylene for total hip replacement  Journal Articles
• Crossover designs versus parallel studies in infertility research  Journal Articles
• Crossover trials with a cumulative response  Journal Articles
• Current Pain-Control Practices and Research☆☆☆★  Conferences
• Cyclophosphamide and plasma exchange in multiple sclerosis  Journal Articles
• DELPHI: accurate deep ensemble model for protein interaction sites prediction  Journal Articles
• Dabigatran monitoring made simple?  Journal Articles
• Daily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study  Journal Articles
• Data based medicine and clinical judgement  Journal Articles
• Data withdrawal in randomized controlled trials: Defining the problem and proposing solutions  Journal Articles
• Dating violence in mid-adolescence Theory, significance, and emerging prevention initiatives  Journal Articles
• Dear Editor  Journal Articles
• Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer: update to study protocol with follow-up extension  Journal Articles
• Declining Enrolment and Other Challenges in IBD Clinical Trials: Causes and Potential Solutions  Journal Articles
• Decolonization in sexual and reproductive health research methods: a scoping review.  Journal Articles
• Decolonizing Scoping Review Methodologies for Literature With, for, and by Indigenous Peoples and the African Diaspora: Dialoguing With the Tensions  Journal Articles
• Defining and measuring health equity effects in research on task shifting interventions in high-income countries: a systematic review protocol  Journal Articles
• Defining clinically important perioperative blood loss and transfusion for the Standardised Endpoints for Perioperative Medicine (StEP) collaborative: a protocol for a scoping review  Journal Articles
• Defining publication bias: protocol for a systematic review of highly cited articles and proposal for a new framework  Journal Articles
• Defining text neck: a scoping review.  Journal Articles
• Defining the Outcome Measures for Out-of-hospital Trials in Acute Pulmonary Edema  Conferences
• Defining the capabilities and competencies of high-performing family physicians: a mixed methods study  Journal Articles
• Definition, reporting, and interpretation of composite outcomes in clinical trials: systematic review.  Journal Articles
• Delayed educational reminders for long-term medication adherence in ST-elevation myocardial infarction (DERLA-STEMI): Protocol for a pragmatic, cluster-randomized controlled trial  Journal Articles
• Delphi consensus study to develop guidelines for the management of adults with borderline personality disorder in the emergency department: a protocol  Journal Articles
• Delphi studies in social and health sciences-Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study.  Journal Articles
• Demystifying trial networks and network meta-analysis  Journal Articles
• Deprescribing anticholinergic and sedative medicines: protocol for a Feasibility Trial (DEFEAT-polypharmacy) in residential aged care facilities  Journal Articles
• Design and Analytic Considerations in Determining the Cost-Effectiveness of Early Intervention in Asthma from a Multinational Clinical Trial  Journal Articles
• Design and Rationale of Health-Related Quality of Life and Patient-Reported Outcomes Assessment in the Frequent Hemodialysis Network Trials  Conferences
• Design and analysis of factorial clinical trials: The impact of one treatment's effectiveness on the statistical power and required sample size of the other  Journal Articles
• Design and assessment of clinical trials on continuous infusion.  Conferences
• Design and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide  Journal Articles
• Design and methods of the MAINTAIN study: A randomized controlled clinical trial of micronutrient and antioxidant supplementation in untreated HIV infection  Journal Articles
• Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran  Journal Articles
• Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial  Journal Articles
• Design and rationale of the Treatment of Acute Coronary Syndromes with Otamixaban trial: A double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non–ST-segment elevation acute coronary syndromes with a planned early invasive strategy  Journal Articles
• Design considerations for randomised trials in orthopaedic fracture surgery  Journal Articles
• Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis  Journal Articles
• Design of the rivaroxaban for heparin-induced thrombocytopenia study  Journal Articles
• Design, Conduct, and Interpretation of Nonrandomized Orthopaedic Studies: A Practical Approach  Journal Articles
• Design, Progress and Challenges of a Double-Blind Trial of Warfarin versus Aspirin for Symptomatic Intracranial Arterial Stenosis  Journal Articles
• Design, analysis and reporting of multi-arm trials and strategies to address multiple testing  Conferences
• Design, analysis, and presentation of crossover trials  Journal Articles
• Designing Medical Informatics Research and Library--Resource Projects to Increase What Is Learned  Journal Articles
• Designing and Analyzing Clinical Trials with Composite Outcomes: Consideration of Possible Treatment Differences between the Individual Outcomes  Journal Articles
• Designing and Reporting Case Series in Plastic Surgery  Journal Articles
• Designing laboratory‐based research studies: is it time for a change?  Journal Articles
• Designing research in vulnerable populations: lessons from HIV prevention trials that stopped early  Journal Articles
• Designing, Conducting, Monitoring, and Analyzing Data from Pragmatic Randomized Clinical Trials: Proceedings from a Multi-stakeholder Think Tank Meeting  Journal Articles
• Detecting, quantifying and adjusting for publication bias in meta-analyses: protocol of a systematic review on methods  Journal Articles
• Determinants of Walking Exercise Among Individuals With Intermittent Claudication  Journal Articles
• Determinants of physical activity in older adults: an umbrella review protocol  Journal Articles
• Determining Optimal Therapy — Randomized Trials in Individual Patients  Journal Articles
• Determining Optimal Therapy — Randomized Trials in Individual Patients  Journal Articles
• Determining causation—A case study: Adrenocorticosteroids and osteoporosis  Journal Articles
• Determining optimal sample sizes for multi-stage randomized clinical trials using value of information methods  Journal Articles
• Determining optimal sample sizes for multistage adaptive randomized clinical trials from an industry perspective using value of information methods  Journal Articles
• Determining the Level of Statistician Participation on Canadian-Based Research Ethics Boards  Journal Articles
• Determining the impact of a new physiotherapist-led primary care model for back pain: protocol for a pilot cluster randomized controlled trial  Journal Articles
• Determining the reporting quality of RCTs in clinical pharmacology  Journal Articles
• Determining the reporting quality of RCTs in clinical pharmacology.  Journal Articles
• Developing Guidance for Donor Intervention Randomized Controlled Trials: Initial Discussions From the Canada-United Kingdom 2022 Workshop  Journal Articles
• Developing Optimal Search Strategies for Detecting Clinically Sound Studies in MEDLINE  Journal Articles
• Developing a reporting item checklist for studies of HIV drug resistance prevalence or incidence: a mixed methods study  Journal Articles
• Developing and Implementing a Triangulation Protocol for Qualitative Health Research  Journal Articles
• Developing optimal search strategies for detecting clinically sound and relevant causation studies in EMBASE  Journal Articles
• Development and Validation of a Set of Palliative Medicine Entrustable Professional Activities: Findings from a Mixed Methods Study  Journal Articles
• Development and application of an outcome-centric approach for conducting overviews of reviews  Journal Articles
• Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study  Journal Articles
• Development and feasibility testing of decision support for patients who are candidates for a prophylactic implantable defibrillator: a study protocol for a pilot randomized controlled trial  Journal Articles
• Development and validation of a Surgical Prioritization and Ranking Tool and Navigation Aid for Head and Neck Cancer (SPARTAN‐HN) in a scarce resource setting: Response to the COVID‐19 pandemic  Journal Articles
• Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations  Journal Articles
• Development and validation of study filters for identifying controlled non‐randomized studies in PubMed and Ovid MEDLINE  Journal Articles
• Development of Disease-Specific Health-Related Quality-of-Life Instruments for Children With Immune Thrombocytopenic Purpura and Their Parents  Journal Articles
• Development of a Core Outcome Set for Studies on Cardiac Disease in Pregnancy (COSCarP): a study protocol  Journal Articles
• Development of a Core Outcome Set for Studies on Obesity in Pregnant Patients (COSSOPP): a study protocol  Journal Articles
• Development of a Framework for Youth- and Family-Specific Engagement in Research: Proposal for a Scoping Review and Qualitative Descriptive Study.  Journal Articles
• Development of a Policy‐Relevant Child Maltreatment Research Strategy  Journal Articles
• Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS)  Journal Articles
• Development of a core outcome set for multimorbidity trials in low/middle-income countries (COSMOS): study protocol  Journal Articles
• Development of a core outcome set for studies on prevention and management of pregnancy-associated venous thromboembolism (COSPVenTE): a study protocol  Journal Articles
• Development of a point of care system for automated coma prognosis: a prospective cohort study protocol  Journal Articles
• Development of a predictive model for loss of functional and cognitive abilities in long-term care home residents: a protocol.  Journal Articles
• Development of an instrument to assess individual student performance in small group tutorials.  Journal Articles
• Development of the Assistance to Participate Scale (APS) for children's play and leisure activities  Journal Articles
• Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses  Journal Articles
• Diagnostic Efficacy of Impedance Plethysmography for Clinically Suspected Deep-Vein Thrombosis  Journal Articles
• Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study  Journal Articles
• Dietary Calcium and Blood Pressure  Journal Articles
• Different meta-analysis methods can change judgements about imprecision of effect estimates: a meta-epidemiological study  Journal Articles
• Differential Student Attrition and Differential Exposure Mask Effects of Problem-Based Learning in Curriculum Comparison Studies  Journal Articles
• Differentiating arrhythmogenic right ventricular cardiomyopathy from right ventricular outflow tract ventricular tachycardia using multilead QRS duration and axis  Journal Articles
• Digitalis for treatment of congestive heart failure in patients in sinus rhythm: a systematic review and meta-analysis  Journal Articles
• Dinoprostone vaginal insert for cervical ripening and labor induction: a meta-analysis  Journal Articles
• Discharge Criteria From Perioperative Physical Therapy  Journal Articles
• Discourse on culture in research on immigrant and migrant workers’ health  Journal Articles
• Discrepancies among megatrials  Journal Articles
• Discrepancies in published data  Journal Articles
• Disparity between statistical and clinical significance in published randomised controlled trials indexed in PubMed: a protocol for a cross-sectional methodological survey  Journal Articles
• Diurnal variation of testosterone and estradiol: a source of bias in comparative studies on breast cancer  Journal Articles
• Diversity of Authors of Publications From the Canadian Critical Care Trials Group*  Journal Articles
• Do Authors Report Surgical Expertise in Open Spine Surgery Related Randomized Controlled Trials? A Systematic Review on Quality of Reporting  Journal Articles
• Do Quality-of-Life Randomized Clinical Trials Support Clinicians in Their Decision-Making?  Journal Articles
• Do You See What I Mean? Indices of Central Tendency  Journal Articles
• Do hip protectors decrease the risk of hip fracture in institutional and community-dwelling elderly? A systematic review and meta-analysis of randomized controlled trials  Journal Articles
• Do physicians need objective measurements to diagnose asthma?  Journal Articles
• Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians  Journal Articles
• Doctor–patient interaction for irritable bowel syndrome in primary care  Journal Articles
• Does Study Design Affect Redislocation Rates After Primary Shoulder Dislocations? A Systematic Review Comparing Prospective and Retrospective Studies  Journal Articles
• Does a "Level I Evidence" rating imply high quality of reporting in orthopaedic randomised controlled trials?  Journal Articles
• Does benefit justify research with children?  Journal Articles
• Does clinical equipoise apply to cluster randomized trials in health research?  Journal Articles
• Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?  Journal Articles
• Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes  Journal Articles
• Double blind, you are the weakest link - goodbye!  Journal Articles
• Driving performance assessments for benzodiazepine receptor agonist–related impairment: a scoping review protocol  Journal Articles
• Drugs and the DST: need for a reappraisal  Journal Articles
• Dynamic systems methods for models of developmental psychopathology  Journal Articles
• Early standardization of high sensitivity troponin T reporting - a lost opportunity  Journal Articles
• Economic Evaluations Conducted for Assessment of Genetic Testing Technologies: A Systematic Review  Journal Articles
• Economic analysis and clinical trials  Journal Articles
• Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol  Journal Articles
• Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial  Journal Articles
• Economic evaluations conducted by Canadian health technology assessment agencies: Where do we stand?  Journal Articles
• Economic evaluations in the critical care literature  Journal Articles
• Economic evaluations of treatment of depressive disorders in adolescents: Protocol for a scoping review  Journal Articles
• Editorial ? Beyond PBL  Journal Articles
• Editorial Comment  Journal Articles
• Editorial: Two cheers for clinical practice guidelines: the hopes and headaches of quality improvement in reproductive healthcare  Journal Articles
• Edoxaban for treatment of venous thromboembolism in patients with cancer  Journal Articles
• Effect of Atenolol on Mortality and Cardiovascular Morbidity after Noncardiac Surgery  Journal Articles
• Effect of Fructose on Body Weight in Controlled Feeding Trials  Journal Articles
• Effect of Metformin vs Placebo on and Metabolic Factors in NCIC CTG MA.32  Journal Articles
• Effect of Smoking Cessation on Mortality After Myocardial Infarction  Journal Articles
• Effect of an interactive text-messaging service on patient retention during the first year of HIV care in Kenya (WelTel Retain): an open-label, randomised parallel-group study  Journal Articles
• Effect of influenza vaccines against mismatched strains: a systematic review protocol  Journal Articles
• Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials  Journal Articles
• Effect of serotonin modulating pharmacotherapies on body mass index and dysglycaemia among children and adolescents: a systematic review and network meta-analysis protocol  Journal Articles
• Effective Ventilation Strategies for Acute Respiratory Distress Syndrome  Journal Articles
• Effectiveness of Percutaneous Coronary Intervention in Patients With Silent Myocardial Ischemia (Post Hoc Analysis of the COURAGE Trial)  Journal Articles
• Effectiveness of Postpartum Support  Journal Articles
• Effectiveness of compression stockings to prevent the post-thrombotic syndrome (The SOX Trial and Bio-SOX biomarker substudy): a randomized controlled trial  Journal Articles
• Effectiveness of implementation strategies in improving physician adherence to guideline recommendations in heart failure: a systematic review protocol  Journal Articles
• Effectiveness of instruction in critical appraisal (evidence-based medicine) skills: a critical appraisal.  Journal Articles
• Effectiveness of knowledge translation tools addressing multiple high-burden chronic diseases affecting older adults: protocol for a systematic review alongside a realist review  Journal Articles
• Effectiveness of metformin to pregnant women with PCOS to reduce spontaneous abortion and gestational diabetes mellitus: a protocol for an overview of reviews  Journal Articles
• Effects of Atrazine in Fish, Amphibians, and Reptiles: An Analysis Based on Quantitative Weight of Evidence  Journal Articles
• Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas  Journal Articles
• Effects of Mode and Order of Administration on Generic Health-Related Quality of Life Scores  Journal Articles
• Effects of ambient air pollution on obesity and ectopic fat deposition: a protocol for a systematic review and meta-analysis  Journal Articles
• Effects of an evidence service on health-system policy makers' use of research evidence: A protocol for a randomised controlled trial  Journal Articles
• Effects of antiretroviral therapy in HIV-positive adults on new HIV infections among young women: a systematic review protocol  Journal Articles
• Effects of electroconvulsive therapy on cognitive functioning in patients with depression: protocol for a systematic review and meta-analysis  Journal Articles
• Effects of health literacy, screening, and participant choice on action plans for reducing unhealthy snacking in Australia: A randomised controlled trial  Journal Articles
• Effects of intravenous hyperalimentation during treatment in patients with small-cell lung cancer.  Journal Articles
• Effects of naltrexone on alcohol self‐administration and craving: meta‐analysis of human laboratory studies  Journal Articles
• Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β₂-agonist fixed-dose combination: RE²SPOND rationale and study design  Journal Articles
• Effects of study design and trends for EVAR versus OSR  Journal Articles
• Efficacy and Safety of Melatonin as an Anxiolytic and Analgesic in the Perioperative Period  Journal Articles
• Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170 255 patients from 76 randomized trials  Journal Articles
• Efficacy of Chinese herbal injections combined with fluoropyrimidine and oxaliplatin-based chemotherapy for advanced colorectal cancer  Journal Articles
• Efficacy of temporary work modifications on disability related to musculoskeletal pain or depressive symptoms—study protocol for a controlled trial  Journal Articles
• Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol  Journal Articles
• El uso de metodología estadística actualizada en la investigación biomédica: el ejemplo de metodología para análisis interino en ensayos clínicos  Journal Articles
• Emerging Designs in Orthopaedics: Expertise-Based Randomized Controlled Trials  Journal Articles
• Emerging Trends in Clinical Trial Design  Journal Articles
• Empirical Testing of the External Validity of a Discrete Choice Experiment to Determine Preferred Treatment Option: The Case of Sleep Apnea  Journal Articles
• Empirical comparison of methods for analyzing multiple time-to-event outcomes in a non-inferiority trial: a breast cancer study  Journal Articles
• Empirical evidence of bias in infertility research: overestimation of treatment effect in crossover trials using pregnancy as the outcome measure  Journal Articles
• Empirically evaluating the impact of adjudicative tribunals in the health sector: context, challenges and opportunities  Journal Articles
• End-of-Life Care for Seniors: Contributions from a New Emerging Team  Journal Articles
• Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: A meta-analysis  Journal Articles
• Endoscopy of the esophagus in gastroesophageal reflux disease: are we losing sight of symptoms? Another perspective  Journal Articles
• Endovascular repair of ruptured abdominal aortic aneurysms: A systematic review and meta-analysis  Journal Articles
• Endovascular therapy for advanced post-thrombotic syndrome: Proceedings from a multidisciplinary consensus panel  Journal Articles
• Engaging First Nation and Inuit communities in asthma management and control: Assessing cultural appropriateness of educational resources  Journal Articles
• Engaging pregnant individuals and healthcare professionals in an international mixed methods study to develop a core outcome set for studies on placenta accreta spectrum disorder (COPAS): a study protocol  Journal Articles
• Enhancing primary reports of randomized controlled trials: Three most common challenges and suggested solutions  Journal Articles
• Environmental Profile of a Community’s Health (EPOCH): An Ecometric Assessment of Measures of the Community Environment Based on Individual Perception  Journal Articles
• Epistemologic Inquiries in Evidence-Based Medicine  Journal Articles
• Equity considerations in utility-based measures of health outcomes in economic appraisals: An adjustment algorithm  Journal Articles
• Equity issues rarely addressed in the development of COVID-19 formal recommendations and good practice statements: a cross-sectional study  Journal Articles
• Erotic gender differentiation in pedophilia  Journal Articles
• Errors in kinematic parameters of a planar joint: Guidelines for optimal experimental design  Journal Articles
• Errors in the implementation, analysis, and reporting of randomization within obesity and nutrition research: a guide to their avoidance  Journal Articles
• Error‐related electrocortical responses in 10‐year‐old children and young adults  Journal Articles
• Establishing a protocol for building a pan-Canadian population-based monitoring system for early childhood development for children with health disorders: Canadian Children’s Health in Context Study (CCHICS)  Journal Articles
• Establishing primary care physician commitment in Canadian long-term care homes: a protocol for a modified e-Delphi study.  Journal Articles
• Establishing thresholds for important benefits considering the harms of screening interventions  Journal Articles
• Estimates of general practitioner workload: a review.  Journal Articles
• Estimating the Power of Indirect Comparisons: A Simulation Study  Journal Articles
• Estimating the current and future cancer burden in Canada: methodological framework of the Canadian population attributable risk of cancer (ComPARe) study  Journal Articles
• Estimation of standard deviations and inverse‐variance weights from an observed range  Journal Articles
• Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study  Journal Articles
• Ethical considerations in conducting surgical research in severe complicated intra-abdominal sepsis  Journal Articles
• Ethical considerations in international HIV vaccine trials: summary of a consultative process conducted by the Joint United Nations Programme on HIV/AIDS (UNAIDS)  Journal Articles
• Ethical review of interpretive research: problems and solutions.  Journal Articles
• Ethically designing research to inform multidimensional, rapidly evolving policy decisions: Lessons learned from the PROMISE HIV Perinatal Prevention Trial  Journal Articles
• European Headache Federation (EHF) critical re-appraisal and meta-analysis of oral drugs in migraine prevention-part 2: flunarizine.  Journal Articles
• Evaluating Agreement: Conducting a Reliability Study  Journal Articles
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• Evaluating a community-based exercise intervention with adults living with HIV: protocol for an interrupted time series study  Journal Articles
• Evaluating comparative effectiveness of psychosocial interventions for persons receiving opioid agonist therapy for opioid use disorder: protocol for a systematic review.  Journal Articles
• Evaluating health related quality of life: An indifference curve interpretation for the time trade-off technique  Journal Articles
• Evaluating injury prevention interventions  Journal Articles
• Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial  Journal Articles
• Evaluating the credibility of anchor based estimates of minimal important differences for patient reported outcomes: instrument development and reliability study  Journal Articles
• Evaluating the design and reporting of pragmatic trials in osteoarthritis research  Journal Articles
• Evaluating the endometabolic and bone health effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukaemia: a systematic review protocol  Journal Articles
• Evaluation and Use of Epidemiological Evidence for Environmental Health Risk Assessment: WHO Guideline Document  Journal Articles
• Evaluation of Diagnostic Assessment Units in Oncology: A Systematic Review  Journal Articles
• Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials  Journal Articles
• Evaluation of WOMAC 20, 50, 70 response criteria in patients treated with hylan G-F 20 for knee osteoarthritis  Journal Articles
• Evaluation of a physiatrist-directed prehabilitation intervention in frail patients with colorectal cancer: a randomised pilot study protocol  Journal Articles
• Evaluation of a research mentorship program in community care  Journal Articles
• Evaluation of innovations in nursing practice: report and discussion  Journal Articles
• Evaluation of intervention reporting in published emergency medicine clinical trials  Journal Articles
• Evaluation of outcome and cost-effectiveness using an FDG PET-guided approach to management of patients with coronary disease and severe left ventricular dysfunction (PARR-2): rationale, design, and methods  Journal Articles
• Evaluation of parent and youth experiences in advisory groups as part of a mental healthcare clinical trial: protocol for a mixed-method study  Journal Articles
• Evaluation of the Effectiveness of Suicide Prevention Programs: A Methodological Perspective  Journal Articles
• Evaluation of the quality of clinical data collection for a pan-Canadian cohort of children affected by inherited metabolic diseases: lessons learned from the Canadian Inherited Metabolic Diseases Research Network  Journal Articles
• Evaluation of the use of GRADE in dentistry systematic reviews and its impact on conclusions: a protocol for a methodological study  Journal Articles
• Evaluation research in public health: barriers to the production and dissemination of outcomes data.  Journal Articles
• Event Adjudication Is Unnecessary in Blinded Trials and May Be Detrimental  Journal Articles
• Event-related potential sensitivity to acoustic and semantic properties of terminal words in sentences  Journal Articles
• Every problem is embedded in a greater whole.  Journal Articles
• Evidence and its uses in health care and research: The role of critical thinking  Journal Articles
• Evidence base of clinical diagnosis: The architecture of diagnostic research  Journal Articles
• Evidence related to a vegetarian diet and metabolic dysfunction-associated steatotic liver disease: protocol for a scoping review  Journal Articles
• Evidence-Based Guidelines—An Introduction  Journal Articles
• Evidence-Based Laboratory Medicine: Addressing Bias, Generalisability and Applicability in Studies on Diagnostic Accuracy. The STARD Initiative  Journal Articles
• Evidence-Based Medicine  Journal Articles
• Evidence-Based Priority Setting for Health Care and Research: Tools to Support Policy in Maternal, Neonatal, and Child Health in Africa  Journal Articles
• Evidence-based decision-making in infectious diseases epidemiology, prevention and control: matching research questions to study designs and quality appraisal tools  Journal Articles
• Evidence-based medicine.  Journal Articles
• Evidence-based practice guidelines for instructing individuals with neurogenic memory impairments: What have we learned in the past 20 years?  Journal Articles
• Evidence-based practice: what it is, why we need it.  Journal Articles
• Evidence‐Based Nursing: Rationale and Resources  Journal Articles
• Examining consensus for a standardised patient assessment in community paramedicine home visits: a RAND/UCLA-modified Delphi Study  Journal Articles
• Examining experiences and system impacts of publicly funded episodic virtual care: protocol for a cross-provincial mixed methods study.  Journal Articles
• Examining the evidence in anesthesia literature: a survey and evaluation of obstetrical postdural puncture headache reports  Journal Articles
• Examining the social determinants of children's developmental health: protocol for building a pan-Canadian population-based monitoring system for early childhood development  Journal Articles
• Exclusion of studies with no events in both arms in meta-analysis impacted the conclusions  Journal Articles
• Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children  Journal Articles
• Executive functioning: A scoping review of the occupational therapy literature / Les fonctions exécutives : une analyse de la portée de la littérature en ergothérapie  Journal Articles
• Exercise research issues in the spinal cord injured population.  Journal Articles
• Expected value of information and decision making in HTA  Journal Articles
• Expertise-based design in surgical trials: a narrative review  Journal Articles
• Exploring design-related bias in clinical studies on receptor genetic polymorphism of hypertension  Journal Articles
• Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics – impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment  Journal Articles
• Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol  Journal Articles
• Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study  Journal Articles
• Exploring the feasibility of using discrete choice experiment (DCE) to elicit preferences among children and adolescents: protocol for a convergent parallel mixed methods study.  Journal Articles
• Exploring the uptake and framing of research evidence on universal screening for intimate partner violence against women: a knowledge translation case study  Journal Articles
• Extending the RIGHT statement for reporting adapted practice guidelines in healthcare: the RIGHT-Ad@pt Checklist protocol  Journal Articles
• Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome—More Research Is Needed  Journal Articles
• FENOTEROL AND FATAL ASTHMA  Journal Articles
• Facilitators, barriers and strategies for health-system guidance implementation: a critical interpretive synthesis protocol  Journal Articles
• Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating ‘not applicable’ responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study  Journal Articles
• Factorial experimental designs  Journal Articles
• Factors affecting exhaled nitric oxide measurements: the effect of sex  Journal Articles
• Factors associated with citation rates in the orthopedic literature.  Journal Articles
• Factors associated with development of gastrointestinal problems in patients with scleroderma: a protocol for a systematic review  Journal Articles
• Factors associated with development of gastrointestinal problems in patients with scleroderma: a systematic review  Journal Articles
• Fatherhood and men's participation in antenatal care in rural sub-Saharan Africa: a scoping review protocol.  Journal Articles
• Feasibility and implementation of a healthy lifestyles program in a community setting in Ontario, Canada: protocol for a pragmatic mixed methods pilot study  Journal Articles
• Feasibility of a Systematic, Comprehensive, One-to-One Training (SCOOT) program for new scooter users: study protocol for a randomized control trial  Journal Articles
• Feasibility of a randomized controlled trial to evaluate the impact of decision boxes on shared decision-making processes  Journal Articles
• Feasibility of the Enhancing Participation In the Community by improving Wheelchair Skills (EPIC Wheels) program: study protocol for a randomized controlled trial  Journal Articles
• Female athlete health domains: a supplement to the International Olympic Committee consensus statement on methods for recording and reporting epidemiological data on injury and illness in sport  Journal Articles
• Financial and family burden associated with cancer treatment in Ontario, Canada  Journal Articles
• Finding Common Ground in Team-Based Qualitative Research Using the Convergent Interviewing Method  Journal Articles
• Fixation using alternative implants for the treatment of hip fractures (FAITH): design and rationale for a multi-centre randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures  Journal Articles
• Fluid Lavage of Open Wounds (FLOW): design and rationale for a large, multicenter collaborative 2 × 3 factorial trial of irrigating pressures and solutions in patients with open fractures  Journal Articles
• Fluid lavage in patients with open fracture wounds (FLOW): an international survey of 984 surgeons  Journal Articles
• Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial  Journal Articles
• Focus group interviews examining attitudes to randomised trials among breast cancer patients and the general community  Journal Articles
• Fondaparinux and prevention of venous thromboembolism after orthopaedic surgery  Journal Articles
• Fondaparinux and prevention of venous thromboembolism after orthopaedic surgery.  Journal Articles
• Fondaparinux in the management of patients with ST-elevation acute myocardial infarction  Journal Articles
• Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin  Journal Articles
• Football-specific extension of the IOC consensus statement: methods for recording and reporting of epidemiological data on injury and illness in sport 2020  Journal Articles
• Forecasting models for human resources in health care  Journal Articles
• Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial  Journal Articles
• Forming the Research Question  Journal Articles
• Fracture Risk in Kidney Transplant Recipients  Journal Articles
• Fragility of Results in Ophthalmology Randomized Controlled Trials  Journal Articles
• Framing of research question using the PICOT format in randomised controlled trials of venous ulcer disease: a protocol for a systematic survey of the literature  Journal Articles
• Fraud versus carelessness  Journal Articles
• Frequent Hemodialysis Network (FHN) randomized trials: Study design  Journal Articles
• From diversity comes understanding: health promotion capacity-building and dissemination research in Canada.  Journal Articles
• From sea to shining sea: making collaborative rural research work  Journal Articles
• Functional Dyspepsia Treatment Trial (FDTT): A double-blind, randomized, placebo-controlled trial of antidepressants in functional dyspepsia, evaluating symptoms, psychopathology, pathophysiology and pharmacogenetics  Journal Articles
• Functional aging in health and heart failure: the COmPLETE Study  Journal Articles
• Functioning and disability in recent research from Cameroon: a narrative synthesis  Journal Articles
• Funding Oncology Clinical Trials: Are Cooperative Group Trials Sustainable?  Journal Articles
• Furosemide and albumin for diuresis of edema (FADE): a study protocol for a randomized controlled trial  Journal Articles
• Further studies are needed to assess the competing therapies for neck pain  Journal Articles
• Future of Evidence Ecosystem Series: Evidence synthesis 2.0: when systematic, scoping, rapid, living, and overviews of reviews come together  Journal Articles
• GENERATING HEALTH TECHNOLOGY ASSESSMENT EVIDENCE FOR RARE DISEASES  Journal Articles
• GRADE Equity Guidelines 2: Considering health equity in GRADE guideline development: Equity extension of the Guideline Development Checklist  Journal Articles
• GRADE Guidance: 31. Assessing the certainty across a body of evidence for comparative test accuracy  Journal Articles
• GRADE Guidelines: 29. Rating the certainty in time-to-event outcomes—Study limitations due to censoring of participants with missing data in intervention studies  Journal Articles
• GRADE Leitlinien: 13. Erstellen von Summary-of-Findings-Tabellen und Evidenzprofilen – kontinuierliche Endpunkte  Journal Articles
• GRADE Leitlinien: 5. Einschätzung der Qualität der Evidenz – Publikationsbias  Journal Articles
• GRADE Leitlinien: 6. Einschätzung der Qualität der Evidenz – Unzureichende Präzision  Journal Articles
• GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale  Journal Articles
• GRADE equity guidelines 3: considering health equity in GRADE guideline development: rating the certainty of synthesized evidence  Journal Articles
• GRADE equity guidelines 4: considering health equity in GRADE guideline development: evidence to decision process  Journal Articles
• GRADE guidance 24 optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines  Journal Articles
• GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence  Journal Articles
• GRADE guidelines: 12. Preparing Summary of Findings tables—binary outcomes  Journal Articles
• GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength  Journal Articles
• GRADE guidelines: 21 part 1. Study design, risk of bias, and indirectness in rating the certainty across a body of evidence for test accuracy  Journal Articles
• GRADE guidelines: 21 part 2. Test accuracy: inconsistency, imprecision, publication bias, and other domains for rating the certainty of evidence and presenting it in evidence profiles and summary of findings tables  Journal Articles
• GRADE guidelines: 7. Rating the quality of evidence—inconsistency  Journal Articles
• GRADE-Leitlinien: 11. Gesamtbeurteilung des Vertrauens in Effektschätzer für einen einzelnen Studienendpunkt und für alle Endpunkte  Journal Articles
• GRADE-Leitlinien: 12. Erstellen von „Summary-of-Findings“-Tabellen – Dichotome Endpunkte  Journal Articles
• GRADE-Leitlinien: 9. Heraufstufen der Qualität der Evidenz  Journal Articles
• Gabapentinoids for chronic low back pain: a protocol for systematic review and meta-analysis of randomised controlled trials  Journal Articles
• Gastric insufflation during cardiopulmonary resuscitation: A study in human cadavers  Journal Articles
• Gastrointestinal recovery after surgery: protocol for a systematic review  Journal Articles
• Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders  Journal Articles
• Generalizability theory for the perplexed: A practical introduction and guide: AMEE Guide No. 68  Journal Articles
• Generalization and the qualitative–quantitative debate  Journal Articles
• Generating evidence on a risk-based monitoring approach in the academic setting – lessons learned  Journal Articles
• Genetic Polymorphisms and Head and Neck Cancer Outcomes: A Review  Journal Articles
• Genome-Scale Phylogeny and the Detection of Systematic Biases  Journal Articles
• Geographies of Risk in Studies Linking Chronic Air Pollution Exposure to Health Outcomes  Journal Articles
• Getting granted  Journal Articles
• Global Anticoagulant Registry in the Field – Venous Thromboembolism (GARFIELD-VTE)  Journal Articles
• Global trends in chronic kidney disease-related mortality: a systematic review protocol  Journal Articles
• Good or best practice statements: proposal for the operationalisation and implementation of GRADE guidance  Journal Articles
• Grades of Recommendation for Antithrombotic Agents  Journal Articles
• Grading quality of evidence and strength of recommendations for diagnostic tests and strategies  Journal Articles
• Grading the evidence: Levels of evidence and grades of recommendation  Journal Articles
• Graphical Representation of Overlap for OVErviews: GROOVE tool  Journal Articles
• Gross motor performance measure for children with cerebral palsy: study design and preliminary findings.  Journal Articles
• Group Intervention Studies in the Cognitive Rehabilitation of Individuals with Traumatic Brain Injury: Challenges Faced by Researchers  Journal Articles
• Group sample sizes in nonregulated health care intervention trials described as randomized controlled trials were overly similar.  Journal Articles
• Guidance for discussants of randomized cancer trials at major meetings.  Journal Articles
• Guidance for the Evaluation of Tuberculosis Diagnostics That Meet the World Health Organization (WHO) Target Product Profiles: An Introduction to WHO Process and Study Design Principles  Journal Articles
• Guidance relevant to the reporting of health equity in observational research: a scoping review protocol  Journal Articles
• Guideline Assessment Project II: statistical calibration informed the development of an AGREE II extension for surgical guidelines  Journal Articles
• Guideline conflict of interest management and methodology heavily impacts on the strength of recommendations: comparison between two iterations of the American College of Chest Physicians Antithrombotic Guidelines  Journal Articles
• Guideline conflict of interest management and methodology heavily impacts on the strength of recommendations: comparison between two iterations of the American College of Chest Physicians Antithrombotic Guidelines.  Journal Articles
• Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024  Journal Articles
• Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024  Journal Articles
• Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024  Journal Articles
• Guideline-based quality assurance: a conceptual framework for the definition of key elements  Journal Articles
• Guidelines for Health Technology Assessment  Journal Articles
• Guidelines for Reporting Outcomes in Trial Protocols  Journal Articles
• Guidelines for Reporting Outcomes in Trial Reports  Journal Articles
• Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed  Journal Articles
• Guidelines for reading literature reviews.  Journal Articles
• Guidelines for the clinical and economic evaluation of health care technologies  Journal Articles
• Guidelines that use the GRADE approach often fail to provide complete economic information for recommendations: A systematic survey  Journal Articles
• HIV prevention and treatment interventions for black men who have sex with men in Canada: a protocol for a scoping systematic review  Journal Articles
• HIV prevention in favour of the choice-disabled in southern Africa: study protocol for a randomised controlled trial  Journal Articles
• HOW TO REALIZE A GOOD EPIDEMIOLOGICAL-STUDY .1. HOW TO PREPARE A STUDY  Journal Articles
• HYEs: Do We Need Them and Can They Fulfil the Promise?  Journal Articles
• Handling of Missing Data  Journal Articles
• Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches  Journal Articles
• Health Status Measures: Strategies and Analytic Methods for Assessing Change Scores  Journal Articles
• Health TAPESTRY Ontario: protocol for a randomized controlled trial to test reproducibility and implementation  Journal Articles
• Health related quality of life among children with cancer in Hyderabad, India  Journal Articles
• Health-Related Quality of Life and Cost-Effectiveness Components of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Rationale and Design  Journal Articles
• Helicobacter pylori test and treat strategy for young dyspeptic patients: new data  Conferences
• Herbal medications for surgical patients: a systematic review protocol  Journal Articles
• Hi! How are you? Response shift, implicit theories and differing epistemologies.  Journal Articles
• Hidradenitis suppurativa odour and drainage scale: a novel method for evaluating odour and drainage in patients with hidradenitis suppurativa  Journal Articles
• Hierarchy of Evidence: From Case Reports to Randomized Controlled Trials  Journal Articles
• Hierarchy of Evidence: Where Observational Studies Fit in and Why We Need Them  Journal Articles
• High Oxygen Delivery to Preserve Exercise Capacity in Patients with Idiopathic Pulmonary Fibrosis Treated with Nintedanib. Methodology of the HOPE-IPF Study  Journal Articles
• Hip Fracture and Proton Pump Inhibitor Therapy: Position Statement  Journal Articles
• Hip fracture evaluation with alternatives of total hip arthroplasty versus hemiarthroplasty (HEALTH): protocol for a multicentre randomised trial  Journal Articles
• Hiring, training, and supporting Peer Research Associates: Operationalizing community-based research principles within epidemiological studies by, with, and for women living with HIV  Journal Articles
• Hormone replacement therapy: a time for pause.  Journal Articles
• Hospital Selection for Unit Cost Estimates in Multicentre Economic Evaluations  Journal Articles
• Hostility and Recidivism in Sexual Offenders  Journal Articles
• How Many Patients? How Many Limbs? Analysis of Patients or Limbs in the Orthopaedic Literature: A Systematic Review  Journal Articles
• How Should Results from Completed Studies Influence Ongoing Clinical Trials?  Journal Articles
• How Strong Is the Evidence?  Journal Articles
• How do financial (dis)incentives influence health behaviour and costs? Protocol for a systematic literature review of randomised controlled trials  Journal Articles
• How have predictors, moderators, mediators, treatment response, remission and resistance been defined and measured in randomised controlled trials for adolescent depression? A scoping review protocol  Journal Articles
• How many, powerfully?  Journal Articles
• How much science is there in injury prevention and control?  Journal Articles
• How qualitative research can contribute to research in the intensive care unit  Journal Articles
• How representative are student convenience samples? A study of literacy and numeracy skills in 32 countries  Conferences
• How to Appraise the Effectiveness of Treatment  Journal Articles
• How to Design a Good Case Series  Journal Articles
• How to Design a Qualitative Health Research Study. Part 1: Design and Purposeful Sampling Considerations.  Journal Articles
• How to Design a Qualitative Health Research Study. Part 2: Data Generation and Analysis Considerations.  Journal Articles
• How to Keep Up with the Medical Literature: I. Why Try to Keep Up and How to Get Started  Journal Articles
• How to Report and Interpret Screening Test Properties: Guidelines for Driving Researchers  Journal Articles
• How to Use a Randomized Clinical Trial Addressing a Surgical Procedure  Journal Articles
• How to Use a Subgroup Analysis  Journal Articles
• How to Use an Article About Quality Improvement  Journal Articles
• How to Use an Article Reporting a Multiple Treatment Comparison Meta-analysis  Journal Articles
• How to assess a survey in surgery  Journal Articles
• How to conduct a high-quality original study on a diagnostic research topic  Journal Articles
• How to conduct a high-quality original study on a prognostic research topic  Journal Articles
• How to conduct a high-quality systematic review on diagnostic research topics  Journal Articles
• How to critique qualitative research articles.  Journal Articles
• How to generalize efficacy results of randomized trials: recommendations based on a systematic review of possible approaches  Journal Articles
• How to increase the value of randomised trials in COPD research  Journal Articles
• How to make cardiology clinical trials more inclusive.  Journal Articles
• How to optimize participant retention and complete follow-up in surgical research  Journal Articles
• How to use an article on therapy or prevention  Journal Articles
• How to use diagnostic test articles in the intensive care unit  Journal Articles
• How to use noninvasive positive airway pressure device data reports to guide clinical care  Journal Articles
• How to work with a subgroup analysis.  Journal Articles
• How well are journal and clinical article characteristics associated with the journal impact factor? a retrospective cohort study  Journal Articles
• Human Laboratory Paradigms in Alcohol Research  Journal Articles
• Human Papillomavirus Triage of Atypical Squamous Cells of Undetermined Significance: Cost-Effective, But At What Cost?  Journal Articles
• Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells  Journal Articles
• Hypothermia Pediatric Head Injury Trial: The Value of a Pretrial Clinical Evaluation Phase  Journal Articles
• Hypothesis Testing in Superiority, Noninferiority, and Equivalence Clinical Trials  Journal Articles
• INSPIRE (INvestigating Social and PractIcal suppoRts at the End of life): Pilot randomised trial of a community social and practical support intervention for adults with life-limiting illness  Journal Articles
• INTENTION TO TREAT ANALYSIS IN CLINICAL RESEARCH: BASIC CONCEPTS FOR CLINICIANS  Journal Articles
• ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research  Journal Articles
• Identifying and understanding the health and social care needs of older adults with multiple chronic conditions and their caregivers: a protocol for a scoping review  Journal Articles
• Identifying candidate quality indicators of tools that support the practice of knowledge translation: a scoping review protocol  Journal Articles
• Identifying genetic and environmental risk factors for chronic orofacial pain syndromes: human models.  Journal Articles
• Identifying non-traditional electronic datasets for population-level surveillance and prevention of cardiometabolic diseases: a scoping review protocol  Journal Articles
• Identifying the domains of context important to implementation science: a study protocol  Journal Articles
• Iloprost  Journal Articles
• Impact of COVID-19 and other pandemics and epidemics on people with pre-existing mental disorders: a systematic review protocol and suggestions for clinical care  Journal Articles
• Impact of Sex on Cardiovascular Outcome in Patients at High Cardiovascular Risk  Journal Articles
• Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations  Journal Articles
• Impact of a new course on students' potential behaviour on encountering ethical dilemmas  Journal Articles
• Impact of cause of death adjudication on the results of the European prostate cancer screening trial  Journal Articles
• Impact of emergency department probiotic treatment of pediatric gastroenteritis: study protocol for the PROGUT (Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment) randomized controlled trial  Journal Articles
• Impact of point-of-care diagnostics on maternal outcomes in HIV-infected women: systematic review and meta-analysis protocol  Journal Articles
• Impact of restricted visitation policies in hospitals on patients, family members and healthcare providers during the COVID-19 pandemic: a scoping review protocol  Journal Articles
• Impact of the Surgical Research Methodology Program on Surgical Residents’ Research Profiles  Journal Articles
• Impact of virtual care on health-related quality of life in children with diabetes mellitus: a systematic review protocol  Journal Articles
• Implementation and impact of an online tool used in primary care to improve access to financial benefits for patients: a study protocol  Journal Articles
• Implementation of an electronic prospective surveillance model for cancer rehabilitation: a mixed methods study protocol.  Journal Articles
• Implementing evidence-based recommended practices for the management of patients with mild traumatic brain injuries in Australian emergency care departments: study protocol for a cluster randomised controlled trial  Journal Articles
• Implementing health research through academic and clinical partnerships: a realistic evaluation of the Collaborations for Leadership in Applied Health Research and Care (CLAHRC)  Journal Articles
• Improved up‐and‐down designs for phase I trials  Journal Articles
• Improving acupuncture research: progress, guidance, and future directions  Journal Articles
• Improving analysis of cognitive outcomes in cardiovascular trials using different statistical approaches.  Journal Articles
• Improving gender equity in critical care medicine: a protocol to establish priorities and strategies for implementation  Journal Articles
• Improving health research among Indigenous Peoples in Canada  Journal Articles
• Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT)  Journal Articles
• Improving reporting of meta-ethnography: the eMERGe reporting guidance  Journal Articles
• Improving reporting of meta‐ethnography: The eMERGe reporting guidance  Journal Articles
• Improving reporting of meta‐ethnography: The eMERGe reporting guidance  Journal Articles
• Improving social justice in observational studies: protocol for the development of a global and Indigenous STROBE-equity reporting guideline  Journal Articles
• Improving the Quality of Abstract Reporting for Phase I Cancer Trials  Journal Articles
• Improving the quality of self-management support in ambulatory cancer care: a mixed-method study of organisational and clinician readiness, barriers and enablers for tailoring of implementation strategies to multisites  Journal Articles
• Improving the reporting of pragmatic trials: an extension of the CONSORT statement  Journal Articles
• Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk  Journal Articles
• In Search of Power and Significance: Issues in the Design and Analysis of Stochastic Cost-Effectiveness Studies in Health Care  Journal Articles
• In the dark The reporting of blinding status in randomized controlled trials  Journal Articles
• Inadequate Reporting of Harm From Randomized Clinical Trials in Top Medical Publications.  Journal Articles
• Inappropriateness of health care in Canada: a systematic review protocol  Journal Articles
• Inconsistencies in the Methodological Framework Throughout Published Studies in High-Impact Orthopaedic Journals  Journal Articles
• Inconsistency between abstract and main text reporting is common in pilot randomized controlled trials of surgical interventions: A methodological survey.  Journal Articles
• Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature  Journal Articles
• Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation  Journal Articles
• Increased Eligibility for Treatment of Chronic Hepatitis C Infection with Shortened Duration of Therapy: Implications for Access to Care and Elimination Strategies in Canada  Journal Articles
• Increased levels of adipokines in bipolar disorder  Journal Articles
• Independent design and conduct of clinical trials  Journal Articles
• Indirect comparison: relative risk fallacies and odds solution  Journal Articles
• Individual opioids, and long- versus short-acting opioids, for chronic noncancer pain  Journal Articles
• Individuals with diabetes preferred that future trials use patient-important outcomes and provide pragmatic inferences  Journal Articles
• Industry Funding by Itself is Not a Reason for Rating Down Studies for Risk of Bias.  Journal Articles
• Industry-sponsored research  Journal Articles
• Infertility:Treatment of male infertility: is it effective? Review and meta-analyses of published randomized controlled trials  Journal Articles
• Influence of statistician involvement on reporting of randomized clinical trials in medical oncology  Journal Articles
• Influencing advance directive completion rates in non-terminally ill patients: a systematic review  Journal Articles
• Initial data supporting the design of the Candesartan in Heart failure — Assessment of Reduction in Mortality and morbidity (CHARM) programme  Journal Articles
• Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design  Journal Articles
• Innovation and placebos in research: a new design of clinical trial  Journal Articles
• Insights on multimorbidity and associated health service use and costs from three population-based studies of older adults in Ontario with diabetes, dementia and stroke  Journal Articles
• Instituto Nacional de Ciência e Tecnologia em Medicina Translacional (INCT-TM): abordagens metodológicas  Journal Articles
• Instructional Design Variations in Internet-Based Learning for Health Professions Education: A Systematic Review and Meta-Analysis  Journal Articles
• Insufficient evidence of the superiority of near-infrared light transillumination over bite-wing digital radiograph for detecting early interproximal carious lesions  Journal Articles
• Insulin therapy in acute coronary syndromes: an appraisal of completed and ongoing randomised trials with important clinical end points  Journal Articles
• Integrated collaborative care teams to enhance service delivery to youth with mental health and substance use challenges: protocol for a pragmatic randomised controlled trial  Journal Articles
• Integrating Clinical Quality Improvement Strategies with Nursing Research  Journal Articles
• Interactive weekly mobile phone text messaging plus motivational interviewing in promotion of breastfeeding among women living with HIV in South Africa: study protocol for a randomized controlled trial  Journal Articles
• Intermittent versus continuous oxygen saturation monitoring for infants hospitalised with bronchiolitis: study protocol for a pragmatic randomised controlled trial  Journal Articles
• International Orthopaedic Multicenter Study in Fracture Care: Coordinating a Large-Scale Multicenter Global Prospective Cohort Study  Journal Articles
• International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019  Journal Articles
• International law’s effects on health and its social determinants: protocol for a systematic review, meta-analysis, and meta-regression analysis  Journal Articles
• International longitudinal registry of patients with atrial fibrillation at risk of stroke: Global Anticoagulant Registry in the FIELD (GARFIELD)  Journal Articles
• International multiphase mixed methods study protocol to develop a cross-cultural patient-reported outcome and experience measure for hand conditions (HAND-Q)  Journal Articles
• International multiphase mixed methods study protocol to develop a patient-reported outcome instrument for children and adolescents with lower limb deformities  Journal Articles
• International phase 1 study protocol to develop a health state classification system for a preference-based measure for women with breast cancer: the BREAST-Q Utility module  Journal Articles
• International point prevalence study of Intensive Care Unit transfusion practices—Pilot study in the Netherlands  Journal Articles
• International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers  Journal Articles
• Interpretation and inference: towards an understanding of methods  Journal Articles
• Interpretation of relative effects  Journal Articles
• Interpreting results from Rasch analysis 2. Advanced model applications and the data-model fit assessment  Journal Articles
• Interpreting trial sequential analysis  Journal Articles
• Interventions for the management of post-COVID-19 condition (long COVID): protocol for a living systematic review and network meta-analysis.  Journal Articles
• Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a protocol for a scoping review of the literature and international policies  Journal Articles
• Intracranial and fatal bleeding according to indication for long‐term oral anticoagulant therapy  Journal Articles
• Intraoperative use of balanced crystalloids versus 0.9% saline: a systematic review and meta-analysis of randomised controlled studies  Journal Articles
• Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial  Journal Articles
• Intrathecal hyperbaric versus isobaric bupivacaine for adult non-caesarean-section surgery: systematic review protocol  Journal Articles
• Intravenous immunoglobulin in Rh hemolytic disease of newborn.  Journal Articles
• Introducing Critical Appraisal to studies of animal models investigating novel therapies in sepsis  Journal Articles
• Introducing the Library of Guidance for Health Scientists (LIGHTS)  Journal Articles
• Introduction to statistical simulations in health research  Journal Articles
• Investigating the appropriateness of different concordance measures in a time‐to‐event setting  Journal Articles
• Investigator experiences with financial conflicts of interest in clinical trials  Journal Articles
• Is NNT now the number needed to traumatize?  Journal Articles
• Is There an Association between STARD Statement Adherence and Citation Rate?  Journal Articles
• Is a Subgroup Claim Believable?  Journal Articles
• Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses  Journal Articles
• Is funding source related to study reporting quality in obesity or nutrition randomized control trials in top-tier medical journals?  Journal Articles
• Is there a benefit of low-dose aspirin in assisted reproduction?  Journal Articles
• Is there a place for the crossover design in infertility trials?  Journal Articles
• Is there a role for physician involvement in introducing research to surrogate decision makers in the intensive care unit? (The Approach trial: a pilot mixed methods study)  Journal Articles
• Is there really misuse and abuse of dabigatran?  Journal Articles
• Issues for reporting results  Journal Articles
• Issues in the planning and conduct of randomised trials  Journal Articles
• Issues of Cost and Efficiency in the Design of Reliability Studies  Journal Articles
• Joint WFH‐ISTH session: issues in clinical trial design  Journal Articles
• Justifying the number of animals for each experiment  Journal Articles
• Key Informants in Applied Qualitative Health Research  Journal Articles
• Key Steps in Conducting Systematic Reviews for Underpinning Clinical Practice Guidelines: Methodology of the European Association of Urology  Journal Articles
• Key design considerations for adaptive clinical trials: a primer for clinicians  Journal Articles
• Key gaps in pathologic reporting for appendiceal mucinous neoplasms: time for universal synoptic reporting?  Journal Articles
• Knowledge transfer to clinicians and consumers by the Cochrane Musculoskeletal Group.  Journal Articles
• LCLUC as an entry point for transdisciplinary research – Reflections from an agriculture land use change study in South Asia  Journal Articles
• LEVEL (Logical Explanations & Visualizations of Estimates in Linear mixed models): recommendations for reporting multilevel data and analyses  Journal Articles
• LMW Heparin for Deep Vein Thrombosis  Journal Articles
• Lack of Diversity in Orthopaedic Trials Conducted in the United States  Journal Articles
• Large Sample Formulae for the Expected Number of Matches in a Category Matched Design  Journal Articles
• Learning from failure-rationale and design for a study about discontinuation of randomized trials (DISCO study)  Journal Articles
• Learning what to expect: context-specific control over intertrial priming effects in singleton search  Journal Articles
• Leaving nothing to chance: how to randomize a clinical trial  Journal Articles
• Left Atrial Appendage Occlusion Study (LAAOS): A randomized clinical trial of left atrial appendage occlusion during routine coronary artery bypass graft surgery for long-term stroke prevention  Journal Articles
• Lessons learned from a resident-led clinical trial in obstetrics  Journal Articles
• Leukotriene Antagonists in Asthma  Journal Articles
• Level of Evidence in Orthopaedic Journals  Journal Articles
• Level of clinical evidence presented at the Society for Vascular Surgery Annual Meeting during a 5-year period (2012-2016)  Journal Articles
• Leveraging pragmatic clinical trial design to advance phosphate management in end-stage renal disease  Journal Articles
• Lies, damned lies, and statistics  Journal Articles
• Life course of retrospective harmonization initiatives: key elements to consider  Journal Articles
• Lipid lowering for primary prevention  Journal Articles
• Living evidence and adaptive policy: perfect partners?  Journal Articles
• Local estimates of population attributable risk  Journal Articles
• Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies  Journal Articles
• Long-Term Predictive Validity of the Risk Matrix 2000  Journal Articles
• Long-term risk of recurrence after discontinuing anticoagulants for a first unprovoked venous thromboembolism: protocol for a systematic review and meta-analysis  Journal Articles
• Looking for the evidence: a systematic review of prevention strategies addressing sport and recreational injury among children and youth  Journal Articles
• Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis  Journal Articles
• Lowering of Glucose in Critical care: a randomized pilot trial  Journal Articles
• Lumbar disc disease.  Journal Articles
• Lymphedema in women with breast cancer: characteristics of patients screened for a randomized trial  Journal Articles
• MATERNAL VITAMIN D SUPPLEMENTATION DURING PREGNANCY AND LACTATION TO PROMOTE INFANT GROWTH IN DHAKA, BANGLADESH (MDIG TRIAL): A RANDOMIZED CONTROLLED TRIAL  Conferences
• MRI ventilation abnormalities predict quality-of-life and lung function changes in mild-to-moderate COPD: longitudinal TINCan study  Journal Articles
• Maelstrom Research guidelines for rigorous retrospective data harmonization  Journal Articles
• Magnetic Resonance Imaging Abnormalities and Psychiatric Illness  Journal Articles
• Making Decisions About Prognosis in Evidence-Based Practice  Journal Articles
• Male participation in prevention programmes of mother to child transmission of HIV: a protocol for a systematic review to identify barriers, facilitators and reported interventions  Journal Articles
• Management of acute musculoskeletal pain (excluding low back pain): protocol for a systematic review and network meta-analysis of randomised trials  Journal Articles
• Management of chronic neuropathic pain: a protocol for a multiple treatment comparison meta-analysis of randomised controlled trials  Journal Articles
• Management of non-severe pregnancy hypertension – A summary of the CHIPS Trial (Control of Hypertension in Pregnancy Study) research publications  Journal Articles
• Management of persistent postconcussion symptoms in youth: a randomised control trial protocol  Journal Articles
• Management of type 2 diabetes using non‐insulin glucose‐lowering therapies: a critical appraisal of clinical practice guidelines with the AGREE II instrument  Journal Articles
• Manual für Methoden und Nutzung versorgungsnaher Daten zur Wissensgenerierung  Journal Articles
• Manual therapy for mechanical neck disorders: a systematic review  Journal Articles
• Mapping the components of the effective implementation of diabetes prevention programmes after gestational diabetes mellitus: a protocol for a scoping review.  Journal Articles
• Maternal psychological distress and parenting stress after the birth of a very low-birth-weight infant.  Journal Articles
• Maternal vitamin D supplementation during pregnancy and lactation to promote infant growth in Dhaka, Bangladesh (MDIG trial): study protocol for a randomized controlled trial  Journal Articles
• Maximizing Oxygen Delivery in High-Risk Surgical Patients  Journal Articles
• McMaster Premium LiteratUre Service (PLUS) performed well for identifying new studies for updated Cochrane reviews  Journal Articles
• Measurement of actions of care-providers in long-term care  Journal Articles
• Measurement of health status  Journal Articles
• Measures assessing attributes of evidence-informed decision-making (EIDM) competence among nurses: a systematic review protocol  Journal Articles
• Measures of retention in HIV care: A protocol for a mixed methods study  Journal Articles
• Measuring and Understanding Treatment Effectiveness in Hand Surgery  Journal Articles
• Measuring asthma control in group studies: do we need airway calibre and rescue β2-agonist use?  Journal Articles
• Measuring behavior change technique delivery and receipt in physical activity behavioral interventions.  Journal Articles
• Measuring the association between behavioural services and outcomes in young children with autism spectrum disorder  Journal Articles
• Measuring the reliability of clinical data: the case for using three observers.  Journal Articles
• Measuring the wellbeing of family caregivers using the time trade-off technique  Journal Articles
• Medicine in the Popular Press: The Influence of the Media on Perceptions of Disease  Journal Articles
• Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer  Journal Articles
• Melatonin and melatonin agonists to prevent and treat delirium in critical illness: a systematic review protocol  Journal Articles
• Members of Minority and Underserved Communities Set Priorities for Health Research  Journal Articles
• Mental Health Supplement to the Ontario Health Survey: Methodology  Journal Articles
• Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?  Journal Articles
• Meta-analysis of Pragmatic and Explanatory Trials  Chapters
• Meta-analysis of the efficacy of antibiotic therapy in eradicating Helicobacter pylori.  Journal Articles
• Meta-analysis: Can We Mix Apples and Oranges?  Journal Articles
• Meta-analysis: well-established and here to stay  Journal Articles
• Meta‐analysis of quantile intervals from different studies with an application to a pulmonary tuberculosis data  Journal Articles
• Method and reporting quality in health professions education research: a systematic review  Journal Articles
• Methodologic Issues in Health Informatics Trials: The Complexities of Complex Interventions  Conferences
• Methodologic issues in trials of antiemetics.  Journal Articles
• Methodologic problems in clinical trials in heart failure  Journal Articles
• Methodological Factors in Studying Medical Graduates  Journal Articles
• Methodological Issues Relevant to Blinding in Physical Medicine and Rehabilitation Research  Journal Articles
• Methodological Issues in Systematic Reviews and Meta-Analyses of Observational Studies in Orthopaedic Research  Journal Articles
• Methodological and Epistemological Considerations in Utilizing Qualitative Inquiry to Develop Interventions  Journal Articles
• Methodological approaches to the design and analysis of nonrandomized intervention studies for the prevention of child and adolescent obesity  Journal Articles
• Methodological challenges in coping and adaptation research.  Journal Articles
• Methodological challenges in design and conduct of randomised controlled trials in acupuncture  Journal Articles
• Methodological design for economic evaluation in Public Access Defibrillation (PAD) trial  Journal Articles
• Methodological idiosyncracies, frameworks and challenges of non-pharmaceutical and non-technical treatment interventions  Journal Articles
• Methodological issues and the impact of age stratification on the proportion of participants with low appendicular lean mass when adjusting for height and fat mass USING LINEAR REGRESSION: RESULTS FROM THE CANADIAN LONGITUDINAL STUDY ON AGING  Journal Articles
• Methodological issues in infertility research  Journal Articles
• Methodological problems in studies of burn survivors and their psychosocial prognosis  Journal Articles
• Methodological problems in the retrospective computation of responsiveness to change: The lesson of Cronbach  Journal Articles
• Methodological review to develop a list of bias items for adaptive clinical trials: Protocol and rationale.  Journal Articles
• Methodological standards in the design and reporting of pilot and feasibility studies in emergency medicine literature: a systematic review.  Journal Articles
• Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol  Journal Articles
• Methodology for Randomized Trials of Patients With Nonvariceal Upper Gastrointestinal Bleeding: Recommendations From an International Consensus Conference  Journal Articles
• Methodology guideline for clinical studies investigating traditional Chinese medicine and integrative medicine  Journal Articles
• Methods and design for the ADAPT study: Application of integrateD Approaches to understanding Physical activity during the Transition to emerging adulthood  Journal Articles
• Methods and guidance on conducting, reporting, publishing and appraising living systematic reviews: a scoping review protocol  Journal Articles
• Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE)  Journal Articles
• Methods for the analysis of bleeding outcomes in randomized trials of PLT transfusion triggers  Journal Articles
• Methods proposed for monitoring the implementation of evidence-based research: a cross-sectional study  Journal Articles
• Methods to Summarize Discrete-Choice Experiments in a Systematic Review: A Scoping Review  Journal Articles
• Methods to convert continuous outcomes into odds ratios of treatment response and numbers needed to treat: meta-epidemiological study  Journal Articles
• Methods, applications, interpretations and challenges of interrupted time series (ITS) data: protocol for a scoping review  Journal Articles
• Mine Is Bigger Than Yours  Journal Articles
• Minimal dataset for post‐registration surveillance of new drugs in hemophilia: communication from the SSC of the ISTH  Journal Articles
• Misclassification of Case-Control Studies in Neurosurgery and Proposed Solutions  Journal Articles
• Misleading hepatitis B test results due to intravenous immunoglobulin administration: implications for a clinical trial of rituximab in immune thrombocytopenia  Journal Articles
• Missing Outcome Data in Recent Perinatal and Neonatal Clinical Trials  Journal Articles
• Missing data in bioarchaeology II: A test of ordinal and continuous data imputation  Journal Articles
• Missing data in longitudinal studies: cross-sectional multiple imputation provides similar estimates to full-information maximum likelihood  Journal Articles
• Modelling heterogeneity variances in multiple treatment comparison meta-analysis – Are informative priors the better solution?  Journal Articles
• Models of care for post-treatment follow-up of adult cancer survivors: a systematic review and quality appraisal of the evidence  Journal Articles
• Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future  Journal Articles
• Monitoring the ACTIVE-W trial: Some issues in monitoring a noninferiority trial  Journal Articles
• Monitoring the randomized trials of the Women's Health Initiative: the experience of the Data and Safety Monitoring Board  Journal Articles
• More Informative Abstracts Revisited  Journal Articles
• More Than a Decade Since the Latest CONSORT Non-inferiority Trials Extension: Do Infectious Diseases Trials Do Enough?  Journal Articles
• More effective and less expensive: lessons from five studies examining community approaches to care  Journal Articles
• Mortality and indicators of traffic-related air pollution  Journal Articles
• Motor control or graded activity exercises for chronic low back pain? A randomised controlled trial  Journal Articles
• Moving forward through consensus: protocol for a modified Delphi approach to determine the top research priorities in the field of orthopaedic oncology  Journal Articles
• Moving from evidence to developing recommendations in guidelines: article 11 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report  Journal Articles
• Moving promising research findings to the clinic: Methodological issues in the design and conduct of clinical trials of retinoids  Journal Articles
• MovingU: A prospective cohort study to understand behavioural and environmental contexts influencing physical activity during the transition into emerging adulthood  Journal Articles
• Multicenter Collaboration in Observational Research: Improving Generalizability and Efficiency  Journal Articles
• Multicenter Study of General Anesthesia. I. Design and Patient Demography  Journal Articles
• Multicenter randomized controlled trial on Duration of Therapy for Thrombosis in Children and Young Adults (the Kids‐DOTT trial): pilot/feasibility phase findings  Journal Articles
• Multifidus and Paraspinal Muscle Group Cross-Sectional Areas of Patients With Low Back Pain and Control Patients: A Systematic Review With a Focus on Blinding  Journal Articles
• Multilevel Modelling of Hierarchical Data in Developmental Studies  Journal Articles
• Multilevel health promotion research: conceptual and analytical considerations.  Journal Articles
• Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study  Journal Articles
• Multimorbidity in children and youth: a scoping review protocol  Journal Articles
• Multiple uses of forest plots in presenting analysis results in health research: A Tutorial  Journal Articles
• N of 1 randomized trials for investigating new drugs  Journal Articles
• N of 1 randomized trials: a commentary  Journal Articles
• NSAID and oesophageal adenocarcinoma: randomised trials needed to correct for bias  Journal Articles
• National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report  Journal Articles
• National suicide management guidelines with family as an interv’ention and suicide mortality rates: a systematic review protocol  Journal Articles
• Need for a large randomized trial to evaluate the effects of digitalis on morbidity and mortality in congestive heart failure  Journal Articles
• Neighbourhood Team Development to promote resident centred approaches in nursing homes: a protocol for a multi component intervention  Journal Articles
• Neonatal Thrombosis: Are We Doing the Right Studies?  Journal Articles
• Nepal Family Cohort study: a study protocol.  Journal Articles
• Neuromuscular Electrical Stimulation for Intensive Care Unit–Acquired Weakness: Protocol and Methodological Implications for a Randomized, Sham-Controlled, Phase II Trial  Journal Articles
• Neuroprogression and Cognitive Functioning in Bipolar Disorder: A Systematic Review  Journal Articles
• New horizons in evidence-based care for older people: individual participant data meta-analysis  Journal Articles
• New measure of parental asthma management for school-age children  Journal Articles
• New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions  Journal Articles
• New strategies for clinical trials in patients with sepsis and septic shock  Journal Articles
• Night-time intra-oesophageal bile and acid exposure in GERD patients failing PPI therapy  Journal Articles
• Nitrous oxide and perioperative cardiac morbidity (ENIGMA-II) Trial: Rationale and design  Journal Articles
• No surgical innovation without evaluation: the IDEAL recommendations  Journal Articles
• Non-Inferiority Trials: A Systematic Review on Methodological Quality and Reporting Standards  Journal Articles
• Non-surgical management of stress urinary incontinence: ambulatory treatments for leakage associated with stress (ATLAS) trial  Journal Articles
• Noninferiority randomised trials in ophthalmology  Journal Articles
• Noninferiority Randomized Controlled Trials  Journal Articles
• Normative comparison standards for measures of cognition in the Canadian Longitudinal Study on Aging (CLSA): Does applying sample weights make a difference?  Journal Articles
• Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial  Journal Articles
• Nurse practitioner/physician collaborative models of care: a scoping review protocol  Journal Articles
• Nutritional profile of rodent diets impacts experimental reproducibility in microbiome preclinical research  Journal Articles
• OVER THE FENCE  Journal Articles
• Observational Studies in Orthopaedic Surgery: The STROBE Statement as a Tool for Transparent Reporting  Journal Articles
• Observed intervention effects for mortality in randomised clinical trials: a methodological study protocol  Journal Articles
• Obtaining medically meaningful answers from an overview of randomized clinical trials  Journal Articles
• Occupational back pain -- an unhelpful polemic  Journal Articles
• On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis  Journal Articles
• On the same page? A qualitative study protocol on collaboration in a multi-laboratory preclinical study  Journal Articles
• Ontario Child Health Study  Journal Articles
• Open synthesis and the coronavirus pandemic in 2020  Journal Articles
• Operationalizing the GRADE-equity criterion to inform guideline recommendations: application to a medical cannabis guideline  Journal Articles
• Opioids for chronic non-cancer pain: a protocol for a systematic review of randomized controlled trials  Journal Articles
• Opportunities and challenges for collaboration in research and practice in injury prevention across work and other settings  Journal Articles
• Optic nerve sheath diameter sonography for the diagnosis of increased intracranial pressure: a systematic review and meta-analysis protocol  Journal Articles
• Optimal Global Value of Information Trials: Better Aligning Manufacturer and Decision Maker Interests and Enabling Feasible Risk Sharing  Journal Articles
• Optimal allocation of participants for the estimation of selection, preference and treatment effects in the two‐stage randomised trial design  Journal Articles
• Optimal clinical trial design using value of information methods with imperfect implementation  Journal Articles
• Optimal search strategies for detecting health services research studies in MEDLINE  Journal Articles
• Optimising the two‐stage randomised trial design when some participants are indifferent in their treatment preferences  Journal Articles
• Optimization of biomolecule separation by combining microscale filtration and design‐of‐experiment methods  Journal Articles
• Optimizing Terminology for Stroke Motor Rehabilitation: Recommendations From the American Congress of Rehabilitation Medicine Stroke Movement Interventions Subcommittee  Journal Articles
• Optimizing multiple Myeloma clinical trials: research direction, addressing limitations, and strategies for improvement.  Journal Articles
• Oral Health in Healthy Aging  Journal Articles
• Organizational Capabilities for Integrating Care  Journal Articles
• Outcome Instruments: Rationale for Their Use  Journal Articles
• Outcome Measures and Implications for Sample-Size Calculations  Journal Articles
• Outcome Measures in Rheumatology - Interventions for medication Adherence (OMERACT-Adherence) Core Domain Set for Trials of Interventions for Medication Adherence in Rheumatology: 5 Phase Study Protocol  Journal Articles
• Outcomes after corrective surgery for congenital dextro-transposition of the great arteries using the arterial switch technique: a protocol for a scoping systematic review  Journal Articles
• Outcomes for patients with the same disease treated inside and outside of randomized trials: a systematic review and meta-analysis  Journal Articles
• Outcomes in the offspring of mothers with pre-diabetes during pregnancy: a protocol for a systematic review  Journal Articles
• Overcoming the limitations of current meta-analysis of randomised controlled trials  Journal Articles
• Overly complex methods may impair pragmatic use of core evidence-based medicine principles  Journal Articles
• Overstated Conclusions of a Pooled Analysis of Bevacizumab in Colon Cancer  Journal Articles
• Overview of results of randomized clinical trials in heart disease. I. Treatments following myocardial infarction  Journal Articles
• Overview of the DIG trial  Journal Articles
• Overweight and obesity management strategies in survivors of paediatric acute lymphoblastic leukaemia: a systematic review protocol  Journal Articles
• PATIENT-REPORTED OUTCOMES IN RARE LYSOSOMAL STORAGE DISEASES: KEY INFORMANT INTERVIEWS AND A SYSTEMATIC REVIEW PROTOCOL  Journal Articles
• POP-Brazil study protocol: a nationwide cross-sectional evaluation of the prevalence and genotype distribution of human papillomavirus (HPV) in Brazil  Journal Articles
• PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews  Journal Articles
• PRISMA harms checklist: improving harms reporting in systematic reviews  Journal Articles
• PROBAST: A Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies  Journal Articles
• PROphylaxis for ThromboEmbolism in Critical Care Trial protocol and analysis plan  Journal Articles
• Parallel experience: how art and art theory can inform ethics in human research  Journal Articles
• Paramedic attitudes and experiences working as a community paramedic: a qualitative survey  Journal Articles
• Parent as Proxy Reporting  Journal Articles
• Participant Characteristics for Dysphagia Research: A Proposed Checklist  Journal Articles
• Patient Eligibility and Trial Design for the Salvage Therapy of Advanced Urothelial Carcinoma  Journal Articles
• Patient Use of Smartphones to Communicate Subjective Data in Clinical Trials  Journal Articles
• Patient preferences for drug therapy in inflammatory arthritis: protocol for a living systematic review and evidence map to inform clinical practice guidelines.  Journal Articles
• Patient, Caregiver, and Clinician Participation in Prioritization of Research Questions in Pediatric Hospital Medicine  Journal Articles
• Patient, caregiver and other knowledge user engagement in consensus-building healthcare initiatives: a scoping review protocol  Journal Articles
• Patient- and Health-Care-Provider-Reported Outcomes to Consider in Research on Pregnancy-Associated Venous Thromboembolism  Journal Articles
• Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives  Journal Articles
• Pedophilia: An Evaluation of Diagnostic and Risk Prediction Methods  Journal Articles
• Perceptions of Health Professionals on Pain in Extremely Low Gestational Age Infants  Journal Articles
• Performance of logistic regression modeling: beyond the number of events per variable, the role of data structure  Journal Articles
• Perioperative randomised controlled trials: to pilot or not to pilot?  Journal Articles
• Persistent methodological problems with evoked potential augmenting-reducing  Journal Articles
• Personalised immunotherapy in sepsis: a scoping review protocol  Journal Articles
• Perspectives from South and East Asia on Clinical and Research Ethics: A Literature Review  Journal Articles
• Perspectives on measuring participation: going forward  Journal Articles
• Perspectives on the sustained engagement with digital health tools: protocol for a qualitative interview study among people living with Inflammatory Bowel Disease or irritable bowel syndrome.  Journal Articles
• Perturbation training to promote safe independent mobility post-stroke: study protocol for a randomized controlled trial  Journal Articles
• Phase 1 Trial Design: Is 3 + 3 the Best?  Journal Articles
• Phase II Stopping Rules That Employ Response Rates and Early Progression  Journal Articles
• Phosphodiesterase-4 inhibition in COPD  Journal Articles
• Pilot and Feasibility Studies in Rehabilitation Research  Journal Articles
• Pilot and feasibility trials in surgery are incompletely reported according to the CONSORT checklist: a meta-research study  Journal Articles
• Pitfalls in the design and analysis of efficacy trials in subfertility: Associate editor's commentary: on the article 'Common statistical errors in the design and analysis of subfertility trials' by A.Vail and E.Gardner.  Journal Articles
• Placebo-controlled trials:  Conferences
• Planned Walking and Communication in SDAT  Journal Articles
• Planning and reporting of quality-of-life outcomes in cancer trials  Journal Articles
• Policymaker and stakeholder perspectives on access to assistive technologies in Canada: challenges and proposed solutions for enhancing equitable access  Journal Articles
• Poor quality patient reported outcome measures bias effect estimates in orthopaedic randomized studies  Journal Articles
• Population Survey Features and Response Rates: A Randomized Experiment  Journal Articles
• Population health intervention research: what is the place for pilot studies?  Journal Articles
• Posing the research question: not so simple  Journal Articles
• Position statement on ethics, equipoise and research on charged particle radiation therapy  Journal Articles
• Potential Pitfall in Using Cumulative Exposure in Exposure‐Response Relationships: Demonstration and Discussion  Journal Articles
• Potential impact of missing outcome data on treatment effects in systematic reviews: imputation study  Journal Articles
• Power curves  Journal Articles
• Practical Model-Based Dose Finding in Early-Phase Clinical Trials  Journal Articles
• Practical Research Methods for Orthopaedic Surgeons  Journal Articles
• Practical research methods for orthopaedic surgeons.  Journal Articles
• Pragmatic monitoring of emerging efficacy data in randomized controlled trials.  Journal Articles
• Pre-trial evaluation of the potential for unblinding in drug trials: A prototype example  Journal Articles
• Preconditioning Shields Against Vascular Events in Surgery (SAVES), a multicentre feasibility trial of preconditioning against adverse events in major vascular surgery: study protocol for a randomised control trial  Journal Articles
• Predicting and Preventing Loss to Follow-up of Adult Trauma Patients in Randomized Controlled Trials  Journal Articles
• Predicting risk and outcomes for frail older adults: a protocol for an umbrella review of available frailty screening tools  Journal Articles
• Prediction of RECRUITment In randomized clinical Trials (RECRUIT-IT)—rationale and design for an international collaborative study  Journal Articles
• Prediction of individual combined benefit and harm for patients with atrial fibrillation considering warfarin therapy: a study protocol  Journal Articles
• Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis  Journal Articles
• Predictive value of the respiratory syncytial virus risk-scoring tool in the term infant in Canada  Conferences
• Predictors of 1-year mortality in adult lung transplant recipients: a systematic review and meta-analysis  Journal Articles
• Predictors of Increased Fragility Index Scores in Surgical Randomized Controlled Trials: An Umbrella Review  Journal Articles
• Predictors of in-hospital mortality among patients with pulmonary tuberculosis: a protocol of systematic review and meta-analysis of observational studies  Journal Articles
• Preference-based disease-specific health-related quality of life instrument for glaucoma: a mixed methods study protocol  Journal Articles
• Preferred Reporting Of Case Series in Surgery (PROCESS) 2023 guidelines  Journal Articles
• Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation  Journal Articles
• Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement  Journal Articles
• Prefrontal Cortex 5-HT₂ Receptors in Depression: An [¹⁸F]Setoperone PET Imaging Study  Journal Articles
• Prehospital prediction of hospital admission for emergent acuity patients transported by paramedics: A population-based cohort study using machine learning  Journal Articles
• Preliminary Development and Validation of a Paediatric Cardiopulmonary Physiotherapy Discharge Tool  Journal Articles
• Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews  Journal Articles
• Presentation structured abstracts of proposals for clinical and epidemiological studies  Journal Articles
• Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies  Journal Articles
• Prevalence of type 2 diabetes in the Islamic Republic of Iran: systematic review and meta-analysis  Journal Articles
• Preventing type 2 diabetes using combination therapy: design and methods of the CAnadian Normoglycaemia Outcomes Evaluation (CANOE) trial  Journal Articles
• Prevention and assessment of infectious diseases among children and adult migrants arriving to the European Union/European Economic Association: A protocol for a suite of systematic reviews for public health and health systems  Journal Articles
• Prevention of Syncope Trial (POST): a randomized clinical trial of beta blockers in the prevention of vasovagal syncope Rationale and study design  Journal Articles
• Prevention of bedside errors in transfusion medicine (PROBE‐TM) study: a cluster‐randomized, matched‐paired clinical areas trial of a simple intervention to reduce errors in the pretransfusion bedside check  Journal Articles
• Preventive health care, 2001 update: screening mammography among women aged 40-49 years at average risk of breast cancer.  Journal Articles
• Primary Realignment vs Suprapubic Cystostomy for the Management of Pelvic Fracture–associated Urethral Injuries: A Systematic Review and Meta-analysis  Journal Articles
• Principles Guiding Nonpandemic Critical Care Research During a Pandemic  Journal Articles
• Principles of Designing a Cohort Study in Orthopaedics  Journal Articles
• Principles of Designing an Orthopaedic Case-Control Study  Journal Articles
• Probiotics for infantile colic: a systematic review  Journal Articles
• Problems in setting up an executing large-scale psychiatric epidemiological studies.  Journal Articles
• Problems of stopping trials early  Journal Articles
• Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671]  Journal Articles
• Prochlorperazine or Metoclopramide?  Journal Articles
• Prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) among hospitalized patients assessed by a rapid response team  Journal Articles
• Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world  Journal Articles
• Project management lessons learned from the multicentre CYCLE pilot randomized controlled trial  Journal Articles
• Promoting Optimal Physical Exercise for Life (PROPEL): aerobic exercise and self-management early after stroke to increase daily physical activity—study protocol for a stepped-wedge randomised trial  Journal Articles
• Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1 trial): study protocol for a pragmatic, stepped-wedge, cluster randomized controlled registry  Journal Articles
• Promoting self-directed learning using a menu of assessment options: the investment model  Journal Articles
• Prophylaxis of Thromboembolism in Critical Care (PROTECT) Trial: a pilot study  Journal Articles
• Proposed Core Set of Items for Measuring Disease Activity in Systemic Juvenile Idiopathic Arthritis  Journal Articles
• Pros and Cons of Composite Endpoints in Anesthesia Trials  Journal Articles
• Pros and Cons of Noninferiority Trials  Journal Articles
• Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial  Journal Articles
• Protein Plus Carbohydrate Does Not Enhance 60-km Time-Trial Performance  Journal Articles
• Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study  Journal Articles
• Protocol for a double-blind, randomised, placebo-controlled pilot study for assessing the feasibility and efficacy of faecal microbiota transplant in a paediatric Crohn’s disease population: PediCRaFT Trial  Journal Articles
• Protocol for a living systematic review for the management of concussion in adults  Journal Articles
• Protocol for a multicenter prospective cohort study evaluating sport activity and development of femoroacetabular impingement in the adolescent hip  Journal Articles
• Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients  Journal Articles
• Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients.  Journal Articles
• Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens  Journal Articles
• Protocol for a prospective, school-based standardisation study of a digital social skills assessment tool for children: The Paediatric Evaluation of Emotions, Relationships, and Socialisation (PEERS) study  Journal Articles
• Protocol for a randomised, placebo-controlled pilot study for assessing feasibility and efficacy of faecal microbiota transplantation in a paediatric ulcerative colitis population: PediFETCh trial  Journal Articles
• Protocol for a scoping review about ethics in transition programmes for adolescents and young adults with neurodisabilities  Journal Articles
• Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data  Journal Articles
• Protocol for a systematic review and meta-analysis investigating the impact of continuous versus intermittent enteral feeding in critically ill patients.  Journal Articles
• Protocol for a systematic review on the role of the gut microbiome in paediatric neurological disorders  Journal Articles
• Protocol for an extended scoping review on the use of virtual nominal group technique in research  Journal Articles
• Protocol for determining the diagnostic validity of physical examination maneuvers for shoulder pathology  Journal Articles
• Protocol for the MATCH study (Mindfulness and Tai Chi for cancer health): A preference-based multi-site randomized comparative effectiveness trial (CET) of Mindfulness-Based Cancer Recovery (MBCR) vs. Tai Chi/Qigong (TCQ) for cancer survivors  Journal Articles
• Protocol for the development of a CONSORT-equity guideline to improve reporting of health equity in randomized trials  Journal Articles
• Protocol for the development of the Chatbot Assessment Reporting Tool (CHART) for clinical advice  Journal Articles
• Psychosocial adjustment in women with breast cancer  Journal Articles
• Psychosocial impacts in populations exposed to solid waste facilities  Journal Articles
• Publication bias in animal research: a systematic review protocol  Journal Articles
• Q-Methodology in Nursing Research  Journal Articles
• Qualitative and quantitative research methods  Journal Articles
• Qualitative case study methodology in nursing research: an integrative review  Journal Articles
• Qualitative health research in the fields of developmental medicine and child neurology  Journal Articles
• Qualitative research in rehabilitation science: opportunities, challenges, and future directions  Journal Articles
• Quality and completeness of, and spin in reporting of, pilot and feasibility studies in hip and knee arthroplasty: a protocol for a methodological survey.  Journal Articles
• Quality and credibility of clinical practice guidelines recommendations for the management of neonatal hypoglycemia. A protocol for a systematic review and recommendations’ synthesis  Journal Articles
• Quality indicators for transition from paediatric to adult care for adolescents with chronic physical and mental illness: protocol for a systematic review  Journal Articles
• Quality of Intervention Research Reporting in Medical Rehabilitation Journals  Journal Articles
• Quality of Reporting of Modern Randomized Controlled Trials in Medical Oncology: A Systematic Review  Journal Articles
• Quality of Reporting of Randomized Controlled Trials in General Endocrinology Literature  Journal Articles
• Quality of Survey Reporting in Nephrology Journals  Journal Articles
• Quality of life as an outcome measure in nursing research. "May you have a long and healthy life".  Journal Articles
• Quality of randomized clinical trials in juvenile idiopathic arthritis  Journal Articles
• Quality of reporting of outcomes in trials of therapeutic interventions for pressure injuries in adults: a systematic methodological survey  Journal Articles
• Quality of reporting of outcomes in trials of therapeutic interventions for pressure ulcers in adults: a protocol for a systematic survey  Journal Articles
• Quality of reporting of surveys in critical care journals  Conferences
• Quality-of-Life Assessment: Patient Compliance With Questionaire Completion  Journal Articles
• Quantitative Sensory Testing Protocols to Evaluate Central and Peripheral Sensitization in Knee OA: A Protocol for a Scoping Review  Journal Articles
• Quantitative bias analysis for external control arms using real-world data in clinical trials: a primer for clinical researchers  Journal Articles
• Quantitative evaluation of single-arm versus randomized phase II cancer clinical trials  Journal Articles
• Quantitative methods for estimating the number of motor units in human muscles  Journal Articles
• Quasi-experimental study designs series—paper 11: supporting the production and use of health systems research syntheses that draw on quasi-experimental study designs  Journal Articles
• Quasi-experimental study designs series—paper 4: uses and value  Journal Articles
• RCT = results confounded and trivial: the perils of grand educational experiments  Journal Articles
• RE-COVERY DVT/PE: Rationale and design of a prospective observational study of acute venous thromboembolism with a focus on dabigatran etexilate  Journal Articles
• REPORTING OF INFORMED CONSENT, STANDARD OF CARE AND POST‐TRIAL OBLIGATIONS IN GLOBAL RANDOMIZED INTERVENTION TRIALS: A SYSTEMATIC SURVEY OF REGISTERED TRIALS  Journal Articles
• REporting quality of PilOt randomised controlled trials in surgery (REPORTS): a methodological survey protocol  Journal Articles
• Radiation Therapy Oncology Group. Research Plan 2002-2006. Gynecology Cancer Working Group.  Journal Articles
• Radiographs of hip fractures were digitally altered to mask surgeons to the type of implant without compromising the reliability of quality ratings or making the rating process more difficult  Journal Articles
• Random error in cardiovascular meta-analyses: How common are false positive and false negative results?  Journal Articles
• Randomised trial of mitral valve repair with leaflet resection versus leaflet preservation on functional mitral stenosis (The CAMRA CardioLink-2 Trial)  Journal Articles
• Randomised trials at the level of the individual  Journal Articles
• Randomized Clinical Trials: The Meeting Place of Medical Practice and Clinical Research  Journal Articles
• Randomized Controlled Trials  Journal Articles
• Randomized Controlled Trials in Long-Term Care Residents with Dementia: A Systematic Review  Journal Articles
• Randomized Phase II Trials: Inevitable or Inadvisable?  Journal Articles
• Randomized Trials in Cardiac Surgery  Journal Articles
• Randomized Trials in Critical Care Nutrition  Journal Articles
• Randomized controlled trial of human papillomavirus testing versus Pap cytology in the primary screening for cervical cancer precursors: Design, methods and preliminary accrual results of the Canadian cervical cancer screening trial (CCCaST)  Journal Articles
• Randomized controlled trials - The what, when, how and why.  Journal Articles
• Randomized controlled trials and neuro-oncology: should alternative designs be considered?  Journal Articles
• Randomized controlled trials in non-pharmacological rehabilitation research: a scoping review of the reporting of sample size calculation, randomization procedure, and statistical analyses  Journal Articles
• Randomized controlled trials in the West African Ebola virus outbreak  Journal Articles
• Randomized controlled trials of herbal interventions underreport important details of the intervention  Journal Articles
• Randomized trials in orthopaedics  Journal Articles
• Randomized trials of public health interventions reported in the Canadian Journal of Public Health: 1966 to 1996.  Journal Articles
• Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis  Journal Articles
• Randomized, controlled clinical trials in sepsis: Has methodological quality improved over time?  Journal Articles
• Randomizing patients by family practice: sample size estimation, intracluster correlation and data analysis  Journal Articles
• Rapid review methods more challenging during COVID-19: commentary with a focus on 8 knowledge synthesis steps  Journal Articles
• Rating certainty when the target threshold is the null and the point estimate is close to the null.  Journal Articles
• Ratio of means for analyzing continuous outcomes in meta-analysis performed as well as mean difference methods  Journal Articles
• Rationale and Design of a Large Study to Evaluate the Renal and Cardiovascular Effects of an ACE Inhibitor and Vitamin E in High-Risk Patients With Diabetes: The MICRO-HOPE Study  Journal Articles
• Rationale and Design of the Echocardiographic Study of Hispanics/Latinos (ECHO-SOL).  Journal Articles
• Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial  Journal Articles
• Rationale and design features of a clinical trial examining the effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT). SCAT Investigators.  Journal Articles
• Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events  Journal Articles
• Rationale and design of AVERROES: Apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment  Journal Articles
• Rationale and design of RE-LY: Randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran  Journal Articles
• Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study  Journal Articles
• Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery  Journal Articles
• Rationale and design of XAMOS: noninterventional study of rivaroxaban for prophylaxis of venous thromboembolism after major hip and knee surgery  Journal Articles
• Rationale and design of a Global Rheumatic Heart Disease Registry: The REMEDY study  Journal Articles
• Rationale and design of a large study to evaluate the renal and cardiovascular effects of an ACE inhibitor and vitamin E in high-risk patients with diabetes. The MICRO-HOPE Study. Microalbuminuria, cardiovascular, and renal outcomes. Heart Outcomes Prevention Evaluation.  Journal Articles
• Rationale and design of a randomized controlled trial evaluating community health worker–based interventions for the secondary prevention of acute coronary syndromes in India (SPREAD)  Journal Articles
• Rationale and design of a study assessing treatment strategies of atrial fibrillation in patients with heart failure: The Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial  Journal Articles
• Rationale and design of the ATTRACT Study: A multicenter randomized trial to evaluate pharmacomechanical catheter-directed thrombolysis for the prevention of postthrombotic syndrome in patients with proximal deep vein thrombosis  Journal Articles
• Rationale and design of the HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial: a protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients  Journal Articles
• Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI)  Journal Articles
• Rationale and design of the randomized prospective ATLAS study: Avoid Transvenous Leads in Appropriate Subjects  Journal Articles
• Rationale and methods of an Evaluation of the Effectiveness of the Community Paramedicine at Home (CP@home) program for frequent users of emergency medical services in multiple Ontario regions: a study protocol for a randomized controlled trial  Journal Articles
• Rationale, Design and Baseline Data of a Randomized, Double-Blind, Controlled Trial Comparing Two Antithrombotic Regimens (a Fixed-Dose Combination of Extended-Release Dipyridamole plus ASA with Clopidogrel) and Telmisartan versus Placebo in Patients with Strokes: The Prevention Regimen for Effectively Avoiding Second Strokes Trial (PRoFESS)  Journal Articles
• Rationale, Design, and Methods of the Preschool ADHD Treatment Study (PATS)  Journal Articles
• Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention)  Journal Articles
• Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo  Journal Articles
• Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease (ONTARGET/TRANSCEND) trials  Journal Articles
• Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis  Journal Articles
• Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) Trial: A randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery  Journal Articles
• Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial  Journal Articles
• Re-analysis of application of haemoclips for non-variceal upper gastrointestinal bleeding data.  Journal Articles
• Re: Breast Reduction Outcome Study  Journal Articles
• Re: Endogenous Steroid Hormone Concentrations and Risk of Breast Cancer Among Premenopausal Women  Journal Articles
• Re: Is Less More? Lessons in Radiation Schedules in Breast Cancer  Journal Articles
• Reader's guide to critical appraisal of cohort studies: 1. Role and design  Journal Articles
• Real-Life Research  Journal Articles
• Real-world studies no substitute for RCTs in establishing efficacy  Journal Articles
• Reasons for the loss of sensitivity and specificity of methodologic MeSH terms and textwords in MEDLINE.  Journal Articles
• Reassessing the Methods of Medical Record Review Studies in Emergency Medicine Research  Journal Articles
• Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts  Journal Articles
• Recent controversies on comparative effectiveness research investigations: Challenges, opportunities, and pitfalls  Journal Articles
• Recommendation mapping of the World Health Organization's guidelines on tuberculosis: A new approach to digitizing and presenting recommendations  Journal Articles
• Recommendations For Core Outcome Domain Set For Whiplash-Associated Disorders (CATWAD)  Journal Articles
• Recommendations for standardized risk factor definitions in pediatric hospital‐acquired venous thromboembolism to inform future prevention trials: communication from the SSC of the ISTH  Journal Articles
• Recommendations for the Use of Common Outcome Measures in Pediatric Traumatic Brain Injury Research  Journal Articles
• Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation  Journal Articles
• Reconcilable Differences: The Marriage of Qualitative and Quantitative Methods  Journal Articles
• Reducing depression in older home care clients: design of a prospective study of a nurse-led interprofessional mental health promotion intervention  Journal Articles
• Reducing the confusion and controversies around pragmatic trials: using the Cardiovascular Health Awareness Program (CHAP) trial as an illustrative example  Journal Articles
• Reduction in Mortality following Elective Major Hip and Knee Surgery: A Systematic Review and Meta-Analysis  Journal Articles
• Redundant Data in the Meta-analysis onHelicobacter pyloriEradication  Journal Articles
• Reflections 1 Year Into the 21-Center National Institutes of Health–Funded WRIST Study: A Primer on Conducting a Multicenter Clinical Trial  Journal Articles
• Reflections on meta-analyses involving trials stopped early for benefit: Is there a problem and if so, what is it?  Journal Articles
• Reflections on the challenges of conducting an international multicentre randomized controlled trial of balance training in addition to pulmonary rehabilitation and its impact on fall incidence in people with COPD  Journal Articles
• Reflections on the opportunities and challenges of applying experience‐based co‐design (EBCD) to phase 1 clinical trials in oncology  Journal Articles
• Registries: Big data, bigger problems?  Journal Articles
• Relation of Distribution- and Anchor-Based Approaches in Interpretation of Changes in Health-Related Quality of Life  Journal Articles
• Relationship between hormonal contraceptives and sleep among women of reproductive age: a systematic review protocol  Journal Articles
• Reliability of 3 Assessment Tools Used to Evaluate Randomized Controlled Trials for Treatment of Neck Pain  Journal Articles
• Reliability of nurses' neurological assessments in the cardiothoracic surgical intensive care unit  Journal Articles
• Reliability of results and interpretation of measures of 3-methylhistidine in muscle interstitium as marker of muscle proteolysis  Journal Articles
• Reliable scar scoring system to assess photographs of burn patients  Journal Articles
• Relying on Others’ Reliability: Challenges in Clinical Teaching Assessment  Journal Articles
• Remote population-based intervention for disruptive behavior at age four: study protocol for a randomized trial of Internet-assisted parent training (Strongest Families Finland-Canada)  Journal Articles
• Renal function and outcomes in acute coronary syndrome: impact of clopidogrel  Journal Articles
• Repeated measures analysis of binary outcomes: Applications to injury research  Journal Articles
• Repetitive Transcranial Magnetic Stimulation for the Treatment of Executive Function Deficits in Autism Spectrum Disorder: Clinical Trial Approach  Journal Articles
• Report From the Ethics Committee for Immunotherapy, American Society for the Immunology of Reproduction  Journal Articles
• Reporting Guidance for Oncologic ¹⁸F-FDG PET/CT Imaging  Journal Articles
• Reporting Guidelines for Imaging Research  Journal Articles
• Reporting Standards for Diagnostic Testing  Journal Articles
• Reporting Time Horizons in Randomized Controlled Trials in Plastic Surgery: A Systematic Review  Journal Articles
• Reporting and Handling of Missing Participant Data in Systematic Reviews of Kidney Transplant Studies  Journal Articles
• Reporting and Publishing Guidelines  Conferences
• Reporting and design of randomized controlled trials for COVID-19: A systematic review  Journal Articles
• Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide  Journal Articles
• Reporting of Clinical Details in Randomized Controlled Trials of Acupuncture for the Treatment of Migraine/Headaches and Nausea/Vomiting  Journal Articles
• Reporting of equity in observational epidemiology: A methodological review  Journal Articles
• Reporting of key methodological and ethical aspects of cluster trials in hemodialysis require improvement: a systematic review  Journal Articles
• Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC)  Journal Articles
• Reporting of planned statistical methods in published surgical randomised trial protocols: a protocol for a methodological systematic review  Journal Articles
• Reporting of primary outcome measures and sample size calculations in randomized controlled trials in dermatology journals  Journal Articles
• Reporting of randomized controlled trial abstracts in dermatology journals according to CONSORT guidelines  Journal Articles
• Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study  Journal Articles
• Reporting results of biomonitoring studies  Journal Articles
• Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey  Journal Articles
• Reproducibility of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) classification: a systematic review  Journal Articles
• Reproductive strategies and seasonal changes in the somatic indices of seven small-bodied fishes in Atlantic Canada in relation to study design for environmental effects monitoring  Journal Articles
• Research Methods for Obtaining Primary Evidence  Journal Articles
• Research Recruitment Practices and Critically Ill Patients. A Multicenter, Cross-Sectional Study (The Consent Study)  Journal Articles
• Research and policy implications of a recently published controlled study in previously untreated haemophilia patients at high risk of inhibitor development  Journal Articles
• Research methods workshop for health professionals in Sierra Leone: an international collaborative project  Journal Articles
• Research on Alzheimer's caregiving in Canada: current status and future directions.  Journal Articles
• Research, Sovereignty and Action: Lessons from a First Nations-Led Study on Aging in Ontario  Journal Articles
• Researching a Best-Practice End-of-Life Care Model for Canada  Journal Articles
• Researching experiences of childhood brain injury: co-constructing knowledge with children through arts-based research methods  Journal Articles
• Resilient Clinical Trial Infrastructure in Response to the COVID-19 Pandemic: Lessons Learned from the TOGETHER Randomized Platform Clinical Trial  Journal Articles
• Resources to facilitate research in advanced practice nursing.  Journal Articles
• Responding to experienced and anticipated discrimination (READ): anti -stigma training for medical students towards patients with mental illness – study protocol for an international multisite non-randomised controlled study  Journal Articles
• Response rates in email vs. mail surveys for urologists: a randomized controlled trial  Journal Articles
• Response to "Potentially Flawed Interpretation of Data by Andriulli et al."  Journal Articles
• Response to Lenert and Kaplan: A Utility Approach to the Assessment of Health-Related Quality of Life  Journal Articles
• Response to Testa: Making Sense of Quality-of-Life Data  Journal Articles
• Response to paper by Lang A, Edwards N, and Fleiszer A  Journal Articles
• Retaining participants in community-based health research: a case example on standardized planning and reporting  Journal Articles
• Rethinking measurement of neighborhood in the context of health research  Journal Articles
• Retrieving randomized controlled trials from medline: a comparison of 38 published search filters  Journal Articles
• Review article: Medical education research: an overview of methods  Journal Articles
• Reviewer agreement trends from four years of electronic submissions of conference abstract  Journal Articles
• Reviewing the research methods literature: principles and strategies illustrated by a systematic overview of sampling in qualitative research  Journal Articles
• Reviewing the reviewers: the quality of reporting in three secondary journals.  Journal Articles
• Revisiting the time course of inter-trial feature priming in singleton search  Journal Articles
• Risk factors for low BMD in healthy men age 50 years or older: a systematic review  Journal Articles
• Risk factors for unintentional injuries due to falls in children aged 0–6 years: a systematic review  Journal Articles
• Risk of Bias from Inclusion of Currently Diagnosed or Treated Patients in Studies of Depression Screening Tool Accuracy: A Cross-Sectional Analysis of Recently Published Primary Studies and Meta-Analyses.  Journal Articles
• Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores.  Journal Articles
• Risk of heart failure and edema associated with the use of pregabalin: a systematic review  Journal Articles
• Risk of recurrent venous thromboembolism after stopping treatment in cohort studies: recommendation for acceptable rates and standardized reporting  Journal Articles
• Risk predictors of severe adverse maternal outcomes in pre-eclampsia: a systematic review and meta-analysis protocol.  Journal Articles
• Risk-Scoring Tool for respiratory syncytial virus prophylaxis in premature infants born at 33–35 completed weeks’ gestational age in Canada  Journal Articles
• Risk-taking behaviors and falls in community-dwelling older adults: a scoping review protocol  Journal Articles
• Rivaroxaban for Preventing Venous Thromboembolism in High-Risk Ambulatory Patients with Cancer: Rationale and Design of the CASSINI Trial  Journal Articles
• Road to Recovery: protocol for a mixed-methods prospective cohort study evaluating the impact of a new model of substance use care in a Canadian setting.  Journal Articles
• Robust bivariate random-effects model for accommodating outlying and influential studies in meta-analysis of diagnostic test accuracy studies  Journal Articles
• Role Preferences in Medical Decision Making: Relevance and Implications for Health Preference Research.  Journal Articles
• Role of patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain: a comprehensive narrative review  Journal Articles
• SELIMETRY—a multicentre I-131 dosimetry trial: a clinical perspective  Journal Articles
• SOLLID – a single centre study to develop methods to investigate the effects of low radiation doses within nuclear medicine, to enable multicentre epidemiological investigations  Journal Articles
• STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies  Journal Articles
• SUNSET: Stereotactic Radiation for Ultracentral Non–Small-Cell Lung Cancer—A Safety and Efficacy Trial  Journal Articles
• Safety and efficacy of perioperative benzodiazepine administration: study protocol for a systematic review and meta-analysis  Journal Articles
• Sample Size and Power in Psychiatric Research^*  Journal Articles
• Sample Size in Clinical Research: When is Enough Enough?  Journal Articles
• Sample size and optimal designs for reliability studies  Journal Articles
• Sample size and power considerations in network meta-analysis  Journal Articles
• Sample size calculations: should the emperor's clothes be off the peg or made to measure?  Journal Articles
• Sample size determination for bibliographic retrieval studies  Journal Articles
• Sample sizes and precision of estimates of sensitivity and specificity from primary studies on the diagnostic accuracy of depression screening tools: a survey of recently published studies.  Journal Articles
• Sample sizes for clinical trials using sputum eosinophils as a primary outcome  Journal Articles
• Scales to Assess the Quality of Randomized Controlled Trials: A Systematic Review  Conferences
• Scanning and form-contingent color aftereffects.  Journal Articles
• Scientific Requirements for Diagnostic Tests in Gastroenterology  Journal Articles
• Scope of Outcomes in Trials and Observational Studies of Interventions Targeting Medication Adherence in Rheumatic Conditions: A Systematic Review  Journal Articles
• Scoping review and systematic reviews are both valuable, but serve different purposes  Journal Articles
• Scoping reviews: reinforcing and advancing the methodology and application  Journal Articles
• Scoping the Field: Identifying Key Research Priorities in HIV and Rehabilitation  Journal Articles
• Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care  Journal Articles
• Screening of ARDS patients using standardized ventilator settings: influence on enrollment in a clinical trial  Journal Articles
• Seamless Designs: Current Practice and Considerations for Early-Phase Drug Development in Oncology  Journal Articles
• Search filters can find some but not all knowledge translation articles in MEDLINE: an analytic survey  Journal Articles
• Searching for rigour in the reporting of mixed methods population health research: a methodological review  Journal Articles
• Searching the scientific literature.  Journal Articles
• Seeing Like a Research Project: Producing “High-Quality Data” in AIDS Research in Malawi  Journal Articles
• Seeing the forests and the trees—innovative approaches to exploring heterogeneity in systematic reviews of complex interventions to enhance health system decision-making: a protocol  Journal Articles
• Segmenting Patients and Physicians Using Preferences from Discrete Choice Experiments  Journal Articles
• Selecting and Appraising Studies for a Systematic Review  Journal Articles
• Selecting the Optimal Level of Clustering: An Approach to Trial Design Decision Making  Journal Articles
• Selection and combination of outcome measures.  Journal Articles
• Selection of patients for randomized controlled trials: Implications of wide or narrow eligibility criteria  Journal Articles
• Selective quotation of evidence in vaccines research  Journal Articles
• Self-Reported Musculoskeletal Disorders Among Visiting and Office Home Care Workers  Journal Articles
• Senior GRADE methodologists encounter challenges as part of WHO guideline development panels: an inductive content analysis  Journal Articles
• Senior high-cost healthcare users’ resource utilization and outcomes: a protocol of a retrospective matched cohort study in Canada  Journal Articles
• Sepsis policy, guidelines and standards in Canada: a jurisdictional scoping review protocol  Journal Articles
• Sequential Monte Carlo for response adaptive randomized trials  Journal Articles
• Serial Habituation in Two-, Three-, and Four-Month-Old Infants  Journal Articles
• Sex Offender Populations and Clinical Efficacy  Journal Articles
• Sex, Gender and Health: Mapping the Landscape of Research and Policy  Journal Articles
• Shadow and substance: values and knowledge.  Journal Articles
• Sharing interim trial results by the Data Safety Monitoring Board with those responsible for the trial’s conduct and progress: a narrative review  Journal Articles
• Should children be screened to undergo early treatment for otitis media with effusion? A systematic review of randomized trials  Journal Articles
• Should physicians initiate β‑blocker therapy in patients undergoing non‑cardiac surgery? Insights from the POISE trial  Journal Articles
• Should study subjects see their previous responses: Data from a randomized control trial  Journal Articles
• Should study subjects see their previous responses?  Journal Articles
• Similarities, reliability and gaps in assessing the quality of conduct of systematic reviews using AMSTAR-2 and ROBIS: systematic survey of nutrition reviews  Journal Articles
• Simple compared to covariate-constrained randomization methods in balancing baseline characteristics: a case study of randomly allocating 72 hemodialysis centers in a cluster trial  Journal Articles
• Simulation Models of Misclassification Error for Single Thresholds of High-Sensitivity Cardiac Troponin I Due to Assay Bias and Imprecision  Journal Articles
• Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments  Journal Articles
• Single session pre-post randomized intervention studies: The good, bad, and ugly  Journal Articles
• Skew‐normal random‐effects model for meta‐analysis of diagnostic test accuracy (DTA) studies  Journal Articles
• Sleep duration and eating behaviours in youth: a scoping review protocol  Journal Articles
• Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial  Journal Articles
• Sleep, biological rhythms and anxiety in the perinatal period: a systematic review protocol  Journal Articles
• Society of Interventional Radiology Reporting Standards for Thoracic Central Vein Obstruction: Endorsed by the American Society of Diagnostic and Interventional Nephrology (ASDIN), British Society of Interventional Radiology (BSIR), Canadian Interventional Radiology Association (CIRA), Heart Rhythm Society (HRS), Indian Society of Vascular and Interventional Radiology (ISVIR), Vascular Access Society of the Americas (VASA), and Vascular Access Society of Britain and Ireland (VASBI)  Journal Articles
• Society of Interventional Radiology Research Reporting Standards for Prostatic Artery Embolization  Journal Articles
• SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX-trial): study design of an international multicenter randomized double-blinded controlled trial of high dose sodium-selenite administration in high-risk cardiac surgical patients  Journal Articles
• Some ethical and design challenges of screening programs and screening tests  Journal Articles
• Sources of bias in diagnostic accuracy studies and the diagnostic process  Journal Articles
• Specialized Inpatient Trauma Treatment for Adults Abused as Children: A Follow-Up Study  Journal Articles
• Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid  Journal Articles
• Spin Reporting Is Common in Pilot Randomized Controlled Trials in Surgery: A Methodological Survey.  Journal Articles
• Stakeholder Perspectives of Attributes and Features of Context Relevant to Knowledge Translation in Health Settings: A Multi-Country Analysis  Journal Articles
• Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children  Journal Articles
• Standardised Outcomes in Nephrology – Chronic Kidney Disease (SONG-CKD): a protocol for establishing a core outcome set for adults with chronic kidney disease who do not require kidney replacement therapy  Journal Articles
• Standardization of electroencephalography for multi-site, multi-platform and multi-investigator studies: insights from the canadian biomarker integration network in depression  Journal Articles
• Standardized reporting of bleeding complications for clinical investigations in acute coronary syndromes: A proposal from the Academic Bleeding Consensus (ABC) Multidisciplinary Working Group  Journal Articles
• Standards for Reporting Interventions in Controlled Trials of Acupuncture: The Stricta Recommendations  Journal Articles
• Starting prophylaxis for venous thromboembolism postoperatively  Journal Articles
• Statistical approaches to harmonize data on cognitive measures in systematic reviews are rarely reported  Journal Articles
• Statistical considerations for research  Journal Articles
• Statistical issues in the design and analysis of expertise‐based randomized clinical trials  Conferences
• Statistical issues in the use of dynamic allocation methods for balancing baseline covariates  Journal Articles
• Statistical methodologies to pool across multiple intervention studies  Journal Articles
• Statistical reporting deficiencies in environmental toxicology  Journal Articles
• Statistical significance and fragility criteria for assessing a difference of two proportions  Journal Articles
• Statistics Commentary Series  Journal Articles
• Statistics Commentary Series  Journal Articles
• Statistics Commentary Series  Journal Articles
• Statistics Commentary Series. Commentary No. 38: Simpson's Paradox and the Mantel-Haenszel χ2  Journal Articles
• Statistics Commentary Series. Commentary No. 41: Randomization  Journal Articles
• Statistics Commentary Series. Commentary No. 42: Minimization  Journal Articles
• Statistics Commentary Series. Commentary No. 43: Patient Preference Trials  Journal Articles
• Statistics Commentary Series. Commentary No. 44: Internal and External Validity  Journal Articles
• Statistics in Brief: The Cluster Randomized Controlled Trial—What Is It and Why Is It Relevant to Research in Surgery?  Journal Articles
• Stellate ganglion block for non-pain indications: a scoping review  Journal Articles
• Steroid use in critically ill septic patients: acknowledging the uncertainty  Journal Articles
• Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial  Journal Articles
• Steroids and Spinal Cord Injury  Journal Articles
• Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial  Journal Articles
• Stopping rules employing response rates, time to progression, and early progressive disease for phase II oncology trials  Journal Articles
• Stories, voices, and explanations: How qualitative methods may help augment emergency medicine research  Journal Articles
• Strategic use of new generation antidepressants for depression: SUN(^_^) D protocol update and statistical analysis plan  Journal Articles
• Strategies and Methods for Research on Sex Differences in Brain and Behavior  Journal Articles
• Strategies for prevention of soccer related injuries: a systematic review  Journal Articles
• Stress Physiology in Infancy and Early Childhood: Cortisol Flexibility, Attunement and Coordination  Journal Articles
• Stress testing journals: a quasi-experimental study of rejection rates of a previously published paper.  Journal Articles
• Student-designed clinical trials: evaluating self-directed learning in pharmacology  Journal Articles
• Studies of Left Ventricular Dysfunction (SOLVD)—Rationale, design and methods: Two trials that evaluate the effect of enalapril in patients with reduced ejection fraction  Journal Articles
• Studies of stroke rehabilitation therapies should report blinding and rationalize use of outcome measurement instruments  Journal Articles
• Study Design and Baseline Characteristics of the Study to Evaluate Carotid Ultrasound Changes in Patients Treated with Ramipril and Vitamin E: SECURE**This study was supported by Research Grant Ul-12363 from the Medicine Research Council of Canada, Ottawa; and by Hoechst Marion Roussel, Laval, Canada, Inc.  Journal Articles
• Study Design and Hierarchy of Evidence for Surgical Decision Making  Journal Articles
• Study Design for the Evaluation of Diagnostic Tests  Journal Articles
• Study Preregistration: Measuring What Matters: Development and Dissemination of a Core Outcome Set for Pediatric Anxiety Disorders Clinical Trials  Journal Articles
• Study design attributes influenced patients' willingness to participate in clinical research: a randomized vignette-based study  Journal Articles
• Study design considerations for assessing the health of fish populations impacted by agriculture in developing countries: a Sri Lankan case study  Journal Articles
• Study protocol for a randomized, controlled, superiority trial comparing the clinical and cost- effectiveness of integrated online mental health assessment-referral-care in pregnancy to usual prenatal care on prenatal and postnatal mental health and infant health and development: the Integrated Maternal Psychosocial Assessment to Care Trial (IMPACT)  Journal Articles
• Study protocol for the Balanced Solution versus Saline in Intensive Care Study (BaSICS): a factorial randomised trial  Journal Articles
• Study protocol for two complementary trials of non-steroidal or opioid analgesia use for children aged 6 to 17 years with musculoskeletal injuries (the No OUCH study)  Journal Articles
• Study protocol: pragmatic randomized control trial of an internet-based intervention (My tools 4 care) for family carers  Journal Articles
• Study-design selection criteria in systematic reviews of effectiveness of health systems interventions and reforms: A meta-review  Journal Articles
• Studying How Patient Engagement Influences Research: A Mixed Methods Study  Journal Articles
• Studying the effect of interventions in injury research: experimental design options  Journal Articles
• Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials  Journal Articles
• Subgroup analyses are seldom possible and subgroup effects are rare in Cochrane HIV systematic reviews  Journal Articles
• Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications  Journal Articles
• Suggesting the Optimal Control Procedure for Acupressure Studies  Journal Articles
• Supported decision-making with persons with dementia: a scoping review protocol in partnership with lived experts  Journal Articles
• Supporting Physical Activity in the Childcare Environment (SPACE): rationale and study protocol for a cluster randomized controlled trial  Journal Articles
• Supporting resident-centred decision-making about transitions from long-term care homes to hospital: a qualitative study protocol.  Journal Articles
• Supporting successful implementation of public health interventions: protocol for a realist synthesis  Journal Articles
• Supporting the improvement and management of prescribing for urinary tract infections (SIMPle): protocol for a cluster randomized trial  Journal Articles
• Surgeon equipoise as an inclusion criterion for the evaluation of nonoperative versus operative treatment of thoracolumbar spinal injuries  Journal Articles
• Surgical ablation of atrial fibrillation: a protocol for a systematic review and meta-analysis of randomised controlled trials  Journal Articles
• Surgical management of malignant pleural mesothelioma: a systematic review and evidence summary  Journal Articles
• Surgical outcomes research--a new paradigm for clinical research?  Journal Articles
• Surgical versus Nonsurgical Treatment for Back Pain  Journal Articles
• Survey Design in Orthopaedic Surgery: Getting Surgeons to Respond  Journal Articles
• Survival Analysis  Journal Articles
• Survival distributions impact the power of randomized placebo-phase design and parallel groups randomized clinical trials  Journal Articles
• Sustained Aeration of Infant Lungs (SAIL) trial: study protocol for a randomized controlled trial  Journal Articles
• Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series  Journal Articles
• Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease  Journal Articles
• Systematic Review on Hormone Receptor Testing in Breast Cancer  Journal Articles
• Systematic Review: Efficacy and Safety of Rituximab for Adults with Idiopathic Thrombocytopenic Purpura  Journal Articles
• Systematic Reviews: The Good, the Bad and the Ugly  Journal Articles
• Systematic evaluation of the methodology of randomized controlled trials of anticoagulation in patients with cancer  Journal Articles
• Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes  Journal Articles
• Systematic review of applied transportability and generalizability analyses: A landscape analysis.  Journal Articles
• Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols  Journal Articles
• Systematic reviewers neglect bias that results from trials stopped early for benefit  Journal Articles
• Systematic reviews experience major limitations in reporting absolute effects  Journal Articles
• Systematic reviews identify important methodological flaws in stroke rehabilitation therapy primary studies: review of reviews  Journal Articles
• Systematic reviews of observational studies of risk of thrombosis and bleeding in urological surgery (ROTBUS): introduction and methodology  Journal Articles
• Systematic reviews of the literature: an introduction to current methods  Journal Articles
• Systematic reviews: the case for rigorous methods and rigorous reporting  Journal Articles
• Systematic survey of the causal language use in systematic reviews of observational studies: a study protocol  Journal Articles
• TB and COVID-19 co-infection: rationale and aims of a global study  Journal Articles
• TEACH: Trial of Education And Compliance in Heart dysfunction chronic disease and heart failure (HF) as an increasing problem  Journal Articles
• THE FEASIBILITY OF MATCHING AND QUOTA SAMPLING IN EPIDEMIOLOGIC STUDIES  Journal Articles
• THE QUALITY OF REPORTING OF RANDOMIZED TRIALS IN THE JOURNAL OF BONE AND JOINT SURGERY FROM 1988 THROUGH 2000  Journal Articles
• Taking a chance: How likely am I to receive my preferred treatment in a clinical trial?  Journal Articles
• Teaching Evidence-Based Complementary and Alternative Medicine: 2. A Conceptual Approach to Causation—Part 1  Journal Articles
• Teaching Evidence-Based Complementary and Alternative Medicine: 2. A Conceptual Approach to Causation—Part 2  Journal Articles
• Team-Based Integrated Knowledge Translation for Enhancing Quality of Life in Long-term Care Settings: A Multi-method, Multi-sectoral Research Design  Journal Articles
• Technology in medicine -- ethics, politics and reality.  Journal Articles
• Telerehabilitation for lower extremity recovery poststroke: a systematic review and meta-analysis protocol  Journal Articles
• Termination of a randomized controlled trial of two vasectomy techniques  Journal Articles
• Testing Quality Improvement Interventions  Journal Articles
• Testing a tool for the classification of study designs in systematic reviews of interventions and exposures showed moderate reliability and low accuracy  Journal Articles
• Testing an audit and feedback-based intervention to improve glycemic control after transfer to adult diabetes care: protocol for a quasi-experimental pre-post design with a control group  Journal Articles
• Testing the Risk of Bias tool showed low reliability between individual reviewers and across consensus assessments of reviewer pairs  Journal Articles
• The 2014 Survey on Living with Chronic Diseases in Canada on Mood and Anxiety Disorders: a methodological overview  Journal Articles
• The ACHRU-CPP versus usual care for older adults with type-2 diabetes and multiple chronic conditions and their family caregivers: study protocol for a randomized controlled trial  Journal Articles
• The Abandoned Trials of Pre-Exposure Prophylaxis for HIV: What Went Wrong?  Journal Articles
• The Aetiology of Sport Injuries  Journal Articles
• The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design  Journal Articles
• The Argentinian mother-and-child contaminant study: a cross-sectional study among delivering women in the cities of Ushuaia and Salta  Journal Articles
• The Bipolar Illness Onset study: research protocol for the BIO cohort study  Journal Articles
• The CHADS2 score for stroke risk stratification in atrial fibrillation – friend or foe?  Journal Articles
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: A double-blind, placebo-controlled trial in patients with ESRD  Conferences
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: a double-blind, placebo-controlled trial in patients with esrd.  Journal Articles
• The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study  Journal Articles
• The Canadian Optimal Therapy of COPD Trial: Design, Organization and Patient Recruitment  Journal Articles
• The Certainty Behind Reporting a Significance Result  Journal Articles
• The Choice of Normative Pediatric Reference Database Changes Spine Bone Mineral Density Z-Scores But Not the Relationship Between Bone Mineral Density and Prevalent Vertebral Fractures  Journal Articles
• The Community Health Assessment Program in the Philippines (CHAP-P) diabetes health promotion program for low- to middle-income countries: study protocol for a cluster randomized controlled trial  Journal Articles
• The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs  Journal Articles
• The Completeness of Reporting (CORE) index identifies important deficiencies in observational study conference abstracts  Journal Articles
• The Consolidated Standards of Reporting Trials (CONSORT) Statement applied to allergen-specific immunotherapy with inhalant allergens: A Global Allergy and Asthma European Network (GA2LEN) article  Journal Articles
• The Coordination and Activity Tracking in CHildren (CATCH) study: rationale and design  Journal Articles
• The Dark Side of Rapid Reviews: A Retreat From Systematic Approaches and the Need for Clear Expectations and Reporting  Journal Articles
• The Defibrillator in Acute Myocardial Infarction Trial (DINAMIT): Study protocol  Journal Articles
• The Design of Randomized Clinical Trials in Critically Ill Patients  Journal Articles
• The Diabetes Health Coaching Randomized Controlled Trial: Rationale, Design and Baseline Characteristics of Adults Living With Type 2 Diabetes  Journal Articles
• The Effects of Probiotics on Symptoms of Depression: Protocol for a Double-Blind Randomized Placebo-Controlled Trial  Journal Articles
• The Efficacy of Leukodepletion to Improve Platelet Transfusion Response: A Critical Appraisal of Clinical Studies  Journal Articles
• The Estimation and Interpretation of Attributable Risk in Health Research  Journal Articles
• The Ethical Conduct of Clinical Research Involving Critically Ill Patients in the United States and Canada  Journal Articles
• The Fluid Study Protocol: A Randomized Controlled Study on the Effects of Bioimpedance Analysis and Vitamin D on Left Ventricular Mass in Peritoneal Dialysis Patients  Journal Articles
• The Fragility of Statistically Significant Findings From Randomized Controlled Trials in Hip and Knee Arthroplasty  Journal Articles
• The Fragility of Statistically Significant Results in Gynaecologic Surgery: A Systematic Review  Journal Articles
• The Future Directions of Research in Cardiac Anesthesiology  Journal Articles
• The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses  Journal Articles
• The HOPE (Heart Outcomes Prevention Evaluation) Study: the design of a large, simple randomized trial of an angiotensin-converting enzyme inhibitor (ramipril) and vitamin E in patients at high risk of cardiovascular events. The HOPE study investigators.  Journal Articles
• The Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth): design, objectives, and procedures  Journal Articles
• The Importance of Pragmatic Study Design to the Scholarly Influence of Surgical Hip Fracture Randomized Controlled Trials  Journal Articles
• The Importance of Reporting Patient Recruitment Details in Phase III Trials  Journal Articles
• The Incidence of Injuries in Young People: I Methodology and Results of a Collaborative Study in Brazil, Chile, Cuba and Venezuela  Journal Articles
• The Inclusion of Minority Groups in Clinical Trials: Problems of Under Representation and Under Reporting of Data  Journal Articles
• The Influence of Display and Statistical Factors on the Interpretation of Metaanalysis Results by Physicians  Journal Articles
• The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) Study  Journal Articles
• The JDRF CCTN CGM TIME Trial: Timing of Initiation of continuous glucose Monitoring in Established pediatric type 1 diabetes: study protocol, recruitment and baseline characteristics  Journal Articles
• The MACTAR Patient Preference Disability Questionnaire--an individualized functional priority approach for assessing improvement in physical disability in clinical trials in rheumatoid arthritis.  Journal Articles
• The National Lung Screening Trial: Overview and Study Design  Journal Articles
• The Need for Large Clinical Studies in Perioperative Medicine  Journal Articles
• The Neighbourhood Effects on Health and Well-being (NEHW) study  Journal Articles
• The Northern Norway mother-and-child contaminant cohort study: implementation, population characteristics and summary of dietary findings  Journal Articles
• The Number of Patients and Events Required to Limit the Risk of Overestimation of Intervention Effects in Meta-Analysis—A Simulation Study  Journal Articles
• The Ontario Mother and Infant Study (TOMIS) III: A multi-site cohort study of the impact of delivery method on health, service use, and costs of care in the first postpartum year  Journal Articles
• The Ottawa Statement implementation guidance document for cluster randomized trials in the hemodialysis setting  Journal Articles
• The PRECISE RCT: Evolution of an Early Septic Shock Fluid Resuscitation Trial  Journal Articles
• The PRISMA 2020 statement: An updated guideline for reporting systematic reviews  Journal Articles
• The PRISMA 2020 statement: an updated guideline for reporting systematic reviews  Journal Articles
• The PROCESS 2020 Guideline: Updating Consensus Preferred Reporting Of CasE Series in Surgery (PROCESS) Guidelines  Journal Articles
• The Pediatric Autism Research Cohort (PARC) Study: protocol for a patient-oriented prospective study examining trajectories of functioning in children with autism  Journal Articles
• The Prospective Studies of Atherosclerosis (Proof-ATHERO) Consortium: Design and Rationale  Journal Articles
• The Quality Initiative in Rectal Cancer (QIRC) trial: study protocol of a cluster randomized controlled trial in surgery  Journal Articles
• The Quality of Reporting of Orthopaedic Randomized Trials with Use of a Checklist for Nonpharmacological Therapies  Journal Articles
• The Rehabilitation Treatment Specification System: Implications for Improvements in Research Design, Reporting, Replication, and Synthesis  Journal Articles
• The Reporting Quality of Randomized Controlled Trial Abstracts in Plastic Surgery  Journal Articles
• The Reporting of Clinical Acupuncture Research: What Do Clinicians Need to Know?  Journal Articles
• The Risk of Bias in Randomized Trials in General Dentistry Journals  Journal Articles
• The Role of Benzodiazepines in the Treatment of Insomnia  Journal Articles
• The Role of Integrated Knowledge Translation in Intervention Research  Journal Articles
• The Scholarly Influence of Orthopaedic Research According to Conventional and Alternative Metrics  Journal Articles
• The Secondary Prevention of Small Subcortical Strokes (SPS3) Study  Journal Articles
• The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience*  Journal Articles
• The Study of Health Assessment and Risk in Ethnic groups (SHARE): rationale and design. The SHARE Investigators.  Journal Articles
• The TRIPSE: A process‐oriented exam for large undergraduate classes  Journal Articles
• The Tactics of Large Randomized Trials  Journal Articles
• The Treatment of Heart Failure  Journal Articles
• The Use of Bayesian Networks to Assess the Quality of Evidence from Research Synthesis: 1.  Journal Articles
• The Use of Cost-effectiveness Analysis in Plastic Surgery Clinical Research  Journal Articles
• The Use of Triangulation in Qualitative Research  Journal Articles
• The Use of the Diary as a Data Collection Technique  Journal Articles
• The Value of Value of Information  Journal Articles
• The Warfarin and Antiplatelet Therapy in Heart Failure Trial (WATCH): rationale, design, and baseline patient characteristics  Journal Articles
• The aetiology, consequences and prevention of barotrauma: a critical review of the literature  Journal Articles
• The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods  Journal Articles
• The burden of cancer attributable to modifiable risk factors in Canada: Methods overview  Journal Articles
• The cameroon mobile phone sms (CAMPS) trial: a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy  Journal Articles
• The case report, case study, and single subject design.  Journal Articles
• The challenge of ensuring affordability, sustainability, consistency, and adaptability in the common metrics agenda  Journal Articles
• The current status of non-radiologist-performed abdominal ultrasonography in paediatrics – a scoping literature review protocol  Journal Articles
• The design of studies testing the effectiveness of risk-guided care has many challenges: a scoping review addressing key considerations  Journal Articles
• The development and validation of a novel questionnaire to measure patient and family satisfaction with end-of-life care: the Canadian Health Care Evaluation Project (CANHELP) Questionnaire  Journal Articles
• The direct healthcare costs attributable to West Nile virus illness in Ontario, Canada: a population-based cohort study using laboratory and health administrative data  Journal Articles
• The effect of auricular acupuncture on anaesthesia: a search for optimal design  Journal Articles
• The effect of berberine on insulin resistance in women with polycystic ovary syndrome: detailed statistical analysis plan (SAP) for a multicenter randomized controlled trial  Journal Articles
• The effect of dornase alfa on ventilation inhomogeneity in patients with cystic fibrosis  Journal Articles
• The effect of loss to follow-up on treatment of blunt traumatic thoracic aortic injury  Journal Articles
• The effect of psychological interventions on the prevention of chronic pain in adults: a systematic review protocol  Journal Articles
• The effectiveness and safety of treatments used for acute diarrhea and acute gastroenteritis in children: protocol for a systematic review and network meta-analysis  Journal Articles
• The effectiveness and safety of treatments used for polycystic ovarian syndrome management in adolescents: a systematic review and network meta-analysis protocol  Journal Articles
• The effectiveness of a Supported Self-management task-shifting intervention for adult depression in Vietnam communities: study protocol for a randomized controlled trial  Journal Articles
• The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol  Journal Articles
• The efficacy and safety of Xuebijing injection in the treatment of radiation pneumonitis  Journal Articles
• The efficacy and safety of glucose control algorithms in intensive care: a pilot study of the Survival Using Glucose Algorithm Regulation (SUGAR) trial  Journal Articles
• The efficacy of fall-risk-increasing drug (FRID) withdrawal for the prevention of falls and fall-related complications: protocol for a systematic review and meta-analysis  Journal Articles
• The end of educational science?  Journal Articles
• The ethical challenges and opportunities of implementing engagement strategies in health research  Journal Articles
• The ever‐shifting source of authority on what works in clinical medicine  Journal Articles
• The evolution of the randomized controlled trial and its role in evidence‐based decision making  Journal Articles
• The greater involvement of people living with AIDS principle: theory versus practice in Ontario's HIV/AIDS community-based research sector  Journal Articles
• The history and development of N-of-1 trials  Journal Articles
• The impact of chronic pain on opioid addiction treatment: a systematic review protocol  Journal Articles
• The impact of deep vein thrombosis in critically ill patients: a meta-analysis of major clinical outcomes.  Journal Articles
• The impact of environmental cadmium exposure on type 2 diabetes risk: a protocol for an overview of systematic reviews  Journal Articles
• The impact of tobacco prices on smoking onset: a methodological review  Journal Articles
• The implementation of sex-and gender-based considerations in exercise-based randomized controlled trials in individuals with stroke: A cross-sectional study.  Journal Articles
• The importance of real-life research in respiratory medicine: manifesto of the Respiratory Effectiveness Group  Journal Articles
• The inadequacy of recent research on computer-assisted instruction  Journal Articles
• The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review  Journal Articles
• The keys to healthy family child care homes intervention: Study design and rationale  Journal Articles
• The level of evidence keeps improving: An updated analysis of the scientific program at the Canadian Association of Paediatric Surgeons Annual Meeting  Conferences
• The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study  Journal Articles
• The neuroscience of recovery and rehabilitation: What have we learned from animal research?  Journal Articles
• The paradox of evidence‐based medicine. Commentary on Gupta (2003), A critical appraisal of evidence‐based medicine: some ethical considerations. Journal of Evaluation in Clinical Practice 9, 111–121  Journal Articles
• The politics of representation: doing and writing "interested" research on midwifery.  Journal Articles
• The practicalists' response  Journal Articles
• The practice of ‘doing’ evaluation: lessons learned from nine complex intervention trials in action  Journal Articles
• The proportions of heterosexual and homosexual pedophiles among sex offenders against children: An exploratory study  Journal Articles
• The provision of medical assistance in dying: protocol for a scoping review  Journal Articles
• The qualitative embedded case study method: Exploring and refining gerontological concepts via qualitative research with older people  Journal Articles
• The quality of QALYs (quality-adjusted-life-years): do QALYs measure what they at least intend to measure?  Journal Articles
• The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement  Journal Articles
• The quality of reporting of trial abstracts is suboptimal: Survey of major general medical journals  Journal Articles
• The randomized placebo-phase design for clinical trials  Journal Articles
• The rationale and design of the Beta‐blocker to LOwer CArdiovascular Dialysis Events (BLOCADE) Feasibility Study  Journal Articles
• The reporting and handling of missing data in longitudinal studies of older adults is suboptimal: a methodological survey of geriatric journals  Journal Articles
• The reporting of observational studies of drug effectiveness and safety: recommendations to extend existing guidelines  Journal Articles
• The reporting of safety among drug systematic reviews was poor before the implementation of the PRISMA harms checklist  Journal Articles
• The reporting quality of N‐of‐1 trials and protocols still needs improvement  Journal Articles
• The research process from ideas to implementation  Journal Articles
• The research question  Journal Articles
• The risk of elevated prolactin levels in pediatric patients exposed to antipsychotics for the treatment of schizophrenia and schizophrenia spectrum disorders: protocol for a systematic review and meta-analysis  Journal Articles
• The role and challenges of cluster randomised trials for global health  Journal Articles
• The role of before-after studies of therapeutic impact in the evaluation of diagnostic technologies  Journal Articles
• The role of early-phase trials and real-world evidence in drug development  Journal Articles
• The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol  Journal Articles
• The role of pragmatism in explaining heterogeneity in meta-analyses of randomised trials: a protocol for a cross-sectional methodological review  Journal Articles
• The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel  Journal Articles
• The study of health assessment and risk in ethnic groups (SHARE): Rationale and design  Journal Articles
• The use of co-design in developing physical activity interventions for older adults: a scoping review protocol  Journal Articles
• The use of surrogate endpoints in clinical trials: focus on clinical trials in cardiovascular diseases  Journal Articles
• The value of information and optimal clinical trial design  Journal Articles
• The ‘Expanded HIV care in opioid substitution treatment’ (EHOST) cluster-randomized, stepped-wedge trial: A study protocol  Journal Articles
• The ‘goddess of randomisation’ in small samples  Journal Articles
• The “parallel-cohort RCT”: Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism  Journal Articles
• Then-of-1 Randomized Controlled Trial: Clinical Usefulness  Journal Articles
• Therapeutic equivalence: all studies are not created equal.  Journal Articles
• Thiazides for Patients with Recurrent Calcium Stones: Still an Open Question  Journal Articles
• Thinking Small: Research Designs Appropriate for Clinical Practice  Journal Articles
• Three challenges described for identifying participants with missing data in trials reports, and potential solutions suggested to systematic reviewers  Journal Articles
• Thrombin generation, bleeding and hemostasis in humans: Protocol for a scoping review of the literature  Journal Articles
• Thrombolysis Compared With Heparin for the Initial Treatment of Pulmonary Embolism  Journal Articles
• Thrombosis prophylaxis in the acutely ill medical patient: insights from the prophylaxis in medical patients with enoxaparin (MEDENOX) trial  Journal Articles
• Time and Expected Value of Sample Information Wait for No Patient  Journal Articles
• Time for reflection on patient’s safety in healthcare  Journal Articles
• Time to rethink clinically important outcomes in platelet transfusion trials  Journal Articles
• Time-dependent analysis in CHF follow-up  Journal Articles
• Tips for learners of evidence-based medicine: 2. Measures of precision (confidence intervals)  Journal Articles
• Tips for learners of evidence-based medicine: 3. Measures of observer variability (kappa statistic)  Journal Articles
• Tips for learners of evidence-based medicine: 4. Assessing heterogeneity of primary studies in systematic reviews and whether to combine their results  Journal Articles
• Tips on overlapping confidence intervals and univariate linear models  Journal Articles
• To the point: a primer on medical education research  Journal Articles
• To “ P ” or not to “ P ”-That is not the question  Journal Articles
• Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial  Journal Articles
• Tools for assessing the scalability of innovations in health: a systematic review  Journal Articles
• Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis  Journal Articles
• Towards Complete and Accurate Reporting of Studies of Diagnostic Accuracy: The STARD Initiative  Journal Articles
• Towards Transparency in the Selection of Published Health Utility Inputs in Cost-Utility Analyses: The Health Utility Application Tool (HAT)  Journal Articles
• Towards a consensus on diagnostic criteria, measurement and trial design of the premenstrual disorders: the ISPMD Montreal consensus  Journal Articles
• Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative  Journal Articles
• Towards systematic reviews that inform health care management and policy-making  Journal Articles
• Traditional knowledge-based lifestyle interventions in the prevention of obesity and type 2 diabetes in Indigenous children in Canada: a systematic review protocol  Journal Articles
• Traditional, complementary and integrative medicine therapies for the treatment of mild/moderate acute COVID-19: protocol for a systematic review and network meta-analysis.  Journal Articles
• Trajectory research in children on the autism spectrum: a scoping review protocol  Journal Articles
• Tranexamic acid in cardiac surgery: a systematic review and meta-analysis (protocol)  Journal Articles
• Transcending the Male–Female Binary in Biomedical Research: Constellations, Heterogeneity, and Mechanism When Considering Sex and Gender  Journal Articles
• Transepithelial versus epithelium-off corneal collagen cross-linking for corneal ectasia: protocol for a systematic review, meta-analysis and trial sequential analysis of randomised controlled trials  Journal Articles
• Transesophageal Echocardiography to Guide Cardioversion in Patients with Atrial Fibrillation  Journal Articles
• Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort study.  Journal Articles
• Transitional care quality indicators to assess quality of care following hospitalisation for chronic obstructive pulmonary disease and heart failure: a systematic review protocol  Journal Articles
• Transparency and completeness of reporting of depression screening tool accuracy studies: A meta-research review of adherence to the Standards for Reporting of Diagnostic Accuracy Studies statement.  Journal Articles
• Trauma Resident Exposure in Canada and Operative Numbers (TraumaRECON): a study protocol for a national multicentre study of operative, nonoperative and structured educational exposures in Canada  Journal Articles
• Treatment allocation in clinical trials  Journal Articles
• Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial  Journal Articles
• Treatment goal setting for complex patients: protocol for a scoping review  Journal Articles
• Trends and recommendations in studies of mouse airway function  Journal Articles
• Trends in chronic rhinosinusitis research in the past three decades  Journal Articles
• Trends in the application of dynamic allocation methods in multi-arm cancer clinical trials  Journal Articles
• Triage Tool Inter-rater Reliability: A Comparison of Live Versus Paper Case Scenarios  Journal Articles
• Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed  Journal Articles
• Trial Protocol: Cognitive functional therapy compared with combined manual therapy and motor control exercise for people with non-specific chronic low back pain: protocol for a randomised, controlled trial.  Journal Articles
• Trial sample size, but not trial quality, is associated with positive study outcome  Journal Articles
• Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses  Journal Articles
• Trial to re-evaluate ultrasound in the treatment of tibial fractures (TRUST): a multicenter randomized pilot study  Journal Articles
• Twenty years of participation of racialised groups in type 2 diabetes randomised clinical trials: a meta-epidemiological review  Journal Articles
• Two alternatives versus the standard Grading of Recommendations Assessment, Development and Evaluation (GRADE) summary of findings (SoF) tables to improve understanding in the presentation of systematic review results: a three-arm, randomised, controlled, non-inferiority trial  Journal Articles
• Two decades of network meta‐analysis: Roadmap to their applications and challenges  Journal Articles
• Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism  Journal Articles
• Type-II Error Rates (Beta Errors) of Randomized Trials in Orthopaedic Trauma  Journal Articles
• Uncertainties about the need for ethics approval in Switzerland: a mixed-methods study  Journal Articles
• Underestimation of pain by health-care providers: towards a model of the process of inferring pain in others.  Journal Articles
• Understanding Measures of Association  Journal Articles
• Understanding Measures of Association: A Primer With Examples From Rehabilitation Research.  Journal Articles
• Understanding Palliative Care on the Heart Failure Care Team: An Innovative Research Methodology  Journal Articles
• Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice  Journal Articles
• Understanding discrimination towards persons experiencing homelessness: A scoping review protocol  Journal Articles
• Understanding how context and culture in six communities can shape implementation of a complex intervention: a comparative case study  Journal Articles
• Understanding the Conceptualization and Operationalization of Trauma‐Informed Care Within and Across Systems: A Critical Interpretive Synthesis  Journal Articles
• Unicorns Do Exist: A Tutorial on “Proving” the Null Hypothesis  Journal Articles
• Unit of Analysis Guide, Part 2: Not Everything That Can Be Counted Counts  Journal Articles
• Unmet Needs and Challenges in Clinical Research of Intracerebral Hemorrhage  Journal Articles
• Unreliable mtDNA data due to nuclear insertions: a cautionary tale from analysis of humans and other great apes  Journal Articles
• Unsettling Knowledge Synthesis Methods Using Institutional Ethnography: Reflections on the Scoping Review as a Critical Knowledge Synthesis Tool  Journal Articles
• Unspoken phenomena: using the photovoice method to enrich phenomenological inquiry  Journal Articles
• Update to the PRISMA guidelines for network meta-analyses and scoping reviews and development of guidelines for rapid reviews: a scoping review protocol.  Journal Articles
• Updating the Canadian clinical practice guideline for managing pediatric obesity: a protocol  Journal Articles
• Uptake of core outcome sets in paediatric clinical trials: a protocol.  Journal Articles
• Use and Interpretation of Composite End Points in Orthopaedic Trials  Journal Articles
• Use of GRADE in Australian clinical practice guidelines: a methodological review protocol  Journal Articles
• Use of Q-Methodology to Identify Nursing Faculty Viewpoints of a Collaborative BScN Program Experience  Journal Articles
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• Use of the Principles of Design Thinking to Address Limitations of Digital Mental Health Interventions for Youth: Viewpoint  Journal Articles
• User's Guide to a Prognostic Study on an Orthopaedic Implant  Journal Articles
• User's guide to the Chiropractic Literature-IB: how to use an article about therapy  Journal Articles
• User's guide to the chiropractic literature-1a: how to use an article about therapy  Journal Articles
• User's guide to the orthopaedic literature: how to use a systematic literature review.  Journal Articles
• Users' guide to detecting misleading claims in clinical research reports  Journal Articles
• Users' guide to evidence-based surgery: how to use an article evaluating surgical interventions. Evidence-Based Surgery Working Group.  Journal Articles
• Users' guide to the surgical literature. How to assess a randomized controlled trial in surgery.  Journal Articles
• Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group  Journal Articles
• Users’ guide to the surgical literature: how to assess a noninferiority trial  Journal Articles
• Users’ guide to the surgical literature: how to assess an article using surrogate end points  Journal Articles
• User’s guide to the chiropractic literature-IA: how to use an article about therapy  Journal Articles
• Using GRADE for evaluating the quality of evidence in hyperbaric oxygen therapy clarifies evidence limitations  Journal Articles
• Using Institutional Ethnography to Understand the Production of Health Care Disparities  Journal Articles
• Using Meta-Analysis in Psychiatric Research  Journal Articles
• Using baseline measurements in the two-period crossover clinical trial  Journal Articles
• Using evidence from randomized trials in fertility practice  Journal Articles
• Using the Maximum Test Statistic in the Two-Period Crossover Clinical Trial  Journal Articles
• Utility of Qualitative Research Findings in Evidence‐Based Public Health Practice  Journal Articles
• VITATOPS, the VITAmins TO Prevent Stroke Trial: Rationale and Design of a Randomised Trial of B-Vitamin Therapy in Patients with Recent Transient Ischaemic Attack or Stroke (NCT00097669) (ISRCTN74743444)  Journal Articles
• Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)  Journal Articles
• Validated questionnaires should not be modified  Journal Articles
• Validation of an index of the quality of review articles  Journal Articles
• Validation of the Imperial College Surgical Assessment Device (ICSAD) for labour epidural placement  Journal Articles
• Validity of a novel method to measure vertical oscillation during running using a depth camera  Journal Articles
• Value of information methods for planning and analyzing clinical studies optimize decision making and research planning  Journal Articles
• Values and other decisional factors regarding treatment of hypercalcaemia of malignancy: a systematic review protocol  Journal Articles
• Variations in stepped-wedge cluster randomized trial design: Insights from the Patient-Centered Care Transitions in Heart Failure trial  Journal Articles
• Varied overground walking task practice versus body weight supported treadmill training in community dwelling adults within one year of stroke: a randomized controlled trial  Conferences
• Varied overground walking-task practice versus body-weight-supported treadmill training in ambulatory adults within one year of stroke: a randomized controlled trial protocol  Journal Articles
• Vasopressin or Epinephrine for Out-of-Hospital Cardiac Arrest  Journal Articles
• Vasopressor use following traumatic injury: protocol for a systematic review  Journal Articles
• Virtue, progress and practice  Journal Articles
• Visual analog scales: do they have a role in the measurement of preferences for health states?  Journal Articles
• Vitamin D’s role in health and disease: How does the present inform our understanding of the past?  Journal Articles
• Vitamin E and bronchopulmonary dysplasia  Journal Articles
• Vitamin K antagonists and cancer: rebuttal  Journal Articles
• Waiver of Informed Consent in Pediatric Resuscitation Research: A Systematic Review  Journal Articles
• Wean Earlier and Automatically with New technology (the WEAN study): a protocol of a multicentre, pilot randomized controlled trial  Journal Articles
• What Do Reported Learning Curves Mean for Orthopaedic Surgeons?  Journal Articles
• What Does the Evidence Tell Us About Design of Future Treatment Trials for Whiplash-Associated Disorders?  Journal Articles
• What Is the State of the Evidence in Anterolateral Ligament Research?  Journal Articles
• What Theories and Methods From Relationship Research Can Contribute to Sex Research  Journal Articles
• What are effective vaccine distribution approaches for equity-deserving and high-risk populations during COVID-19? Exploring best practices and recommendations in Canada: protocol for a mixed-methods multiple case codesign study  Journal Articles
• What are the best methodologies for rapid reviews of the research evidence for evidence-informed decision making in health policy and practice: a rapid review  Journal Articles
• What are the information priorities for cancer patients involved in treatment decisions? An experienced surrogate study in Hodgkin's disease  Journal Articles
• What are we confident about?  Journal Articles
• What counts as patient-important upper gastrointestinal bleeding in the ICU? A mixed-methods study protocol of patient and family perspectives  Journal Articles
• What do we mean by web-based learning? A systematic review of the variability of interventions  Journal Articles
• What does this study test, and why?  Journal Articles
• What is Wrong With Systematic Reviews and Meta-Analyses: If You Want the Right Answer, Ask the Right Question!  Journal Articles
• What is a network meta-analysis and how can we use it to inform clinical practice?  Journal Articles
• What is “quality of evidence” and why is it important to clinicians?  Journal Articles
• What makes public health studies ethical? Dissolving the boundary between research and practice  Journal Articles
• What risks should be permissible in controlled human infection model studies?  Journal Articles
• What should be reported in a methods section on utility assessment?  Journal Articles
• What to do with all the AGREEs? The AGREE portfolio of tools to support the guideline enterprise  Journal Articles
• When is a randomised controlled trial health equity relevant? Development and validation of a conceptual framework  Journal Articles
• When is informed consent required in cluster randomized trials in health research?  Journal Articles
• When is it safe to stop for safety?  Journal Articles
• When to replicate systematic reviews of interventions: consensus checklist  Journal Articles
• When words fail us: An integrative review of innovative elicitation techniques for qualitative interviews.  Journal Articles
• Where Would You Turn for Help? Older Adults' Awareness of Community Support Services  Journal Articles
• While modern medicine evolves continuously, evidence-based research methodology remains: how register studies should be interpreted and appreciated  Journal Articles
• Who's minding the shop? The role of Canadian research ethics boards in the creation and uses of registries and biobanks  Journal Articles
• Why observational studies are key? Health status outcomes and clinical care pathways.  Journal Articles
• Why recent editorial review articles regarding randomized methodology do not reflect reality  Journal Articles
• Willingness-to-pay (WTP): the new-old kid on the economic evaluation block.  Journal Articles
• Women's Views of Their Experiences in the CHIPS (Control of Hypertension in Pregnancy Study) Pilot Trial  Journal Articles
• Women's and care providers' perspectives of quality prenatal care: a qualitative descriptive study  Journal Articles
• Women’s Experiences of Participating in the Early External Cephalic Version 2 Trial  Journal Articles
• Working in the Margins: Women's Experiences of Stress and Occupational Health Problems in Part-Time and Casual Retail Jobs  Journal Articles
• Writing place: a comparison of nursing research and health geography  Journal Articles
• Written informed consent and selection bias in observational studies using medical records: systematic review  Journal Articles
• X-ray cross correlation analysis uncovers hidden local symmetries in disordered matter  Journal Articles
• XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation  Journal Articles
• Ximelagatran for Secondary Prevention of Venous Thromboembolism  Journal Articles
• Ximelagatran or warfarin in atrial fibrillation?  Journal Articles
• [10 years of stagnant clinical research in the Italian academic context.].  Journal Articles
• [Four numbers and a bit more basic knowledge of mathematics].  Journal Articles
• [How to carry out a good epidemiological study. I. Preparation of a study].  Journal Articles
• [How to carry out a good epidemiological study. II. Collection of data, writing of the report, evaluation of the completed work].  Journal Articles
• [Risk of bias assessment: (7) Assessing Bias in Studies of Prognostic Factors].  Journal Articles
• [Risk of ovarian cancer in women treated for infertility].  Journal Articles
• [Risk of ovarian cancer in women treated for infertility].  Journal Articles
• [The number needed to treat (NNT) and the number needed to harm (NNH)].  Journal Articles
• β-Blockers in sepsis: protocol for a systematic review and meta-analysis of randomised control trials  Journal Articles
• β2-agonists  Journal Articles
• ‘The problem is small enough, the problem is big enough’: a qualitative study of health technology assessment and public policy on drug funding decisions for children  Journal Articles
• “Nothing About Us, without Us.” How Community-Based Participatory Research Methods Were Adapted in an Indigenous End-of-Life Study Using Previously Collected Data  Journal Articles
• “Push” versus “Pull” for mobilizing pain evidence into practice across different health professions: A protocol for a randomized trial  Journal Articles