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A Prospective Comparison of Four Study Designs...
Journal article

A Prospective Comparison of Four Study Designs Used in Assessing Safety and Effectiveness of Drug Therapy in Hypertension Management*

Abstract

The objective of the study was to compare prospectively the impact of study design on drug therapy safety and effectiveness data obtained in hypertension management. The main study was a randomized controlled clinical trial of four different prospective study designs used in postmarketing assessment involving 1008 primary care practices in nine Canadian provinces. Two thousand nine hundred sixty-four patients with mild to moderate hypertension …

Authors

Levine MAH; Hamet P; Novosel S; Jolain B

Journal

American Journal of Hypertension, Vol. 10, No. 11, pp. 1191–1200

Publisher

Oxford University Press (OUP)

Publication Date

11 1997

DOI

10.1016/s0895-7061(97)00227-6

ISSN

0895-7061