Journal article
Adaptive clinical trials in surgery: A scoping review of methodological and reporting quality
Abstract
IMPORTANCE: Adaptive surgical trials are scarce, but adopting these methods may help elevate the quality of surgical research when large-scale RCTs are impractical.
OBJECTIVE: Randomized-controlled trials (RCTs) are the gold standard for evidence-based healthcare. Despite an increase in the number of RCTs, the number of surgical trials remains unchanged. Adaptive clinical trials can streamline trial design and time to trial reporting. The …
Authors
Staibano P; Oulousian E; McKechnie T; Thabane A; Luo S; Gupta MK; Zhang H; Pasternak JD; Au M; Parpia S
Journal
PLOS ONE, Vol. 19, No. 5,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0299494
ISSN
1932-6203