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An N of 1 Service: Applying the Scientific Method...
Journal article

An N of 1 Service: Applying the Scientific Method in Clinical Practice

Abstract

The N of 1 service at our institution acts as a full referral service for clinicians who want a definitive answer to a difficult management question, and an instructional environment for clinicians who have more time and want to learn to run their own N of 1 RCT. The trial design is a double blind, randomized pair, multiple crossover. A number of methodologic issues are discussed, such as appropriateness of the patients problem to N of 1 …

Authors

Keller JL; Guyatt GH; Roberts RS; Adachi JD; Rosenbloom D

Journal

Scandinavian Journal of Gastroenterology, Vol. 23, No. sup147, pp. 22–29

Publisher

Taylor & Francis

Publication Date

1 1988

DOI

10.3109/00365528809099154

ISSN

0036-5521