Journal article
Methods to convert continuous outcomes into odds ratios of treatment response and numbers needed to treat: meta-epidemiological study
Abstract
BACKGROUND: Clinicians find standardized mean differences (SMDs) calculated from continuous outcomes difficult to interpret. Our objective was to determine the performance of methods in converting SMDs or means to odds ratios of treatment response and numbers needed to treat (NNTs) as more intuitive measures of treatment effect.
METHODS: Meta-epidemiological study of large-scale trials (≥ 100 patients per group) comparing active treatment with …
Authors
da Costa BR; Rutjes AW; Johnston BC; Reichenbach S; Nüesch E; Tonia T; Gemperli A; Guyatt GH; Jüni P
Journal
International Journal of Epidemiology, Vol. 41, No. 5, pp. 1445–1459
Publisher
Oxford University Press (OUP)
Publication Date
October 1, 2012
DOI
10.1093/ije/dys124
ISSN
0300-5771