Conference
Design, analysis and reporting of multi-arm trials and strategies to address multiple testing
Abstract
BACKGROUND: It is unclear how multiple treatment comparisons are managed in the analysis of multi-arm trials, particularly related to reducing type I (false positive) and type II errors (false negative).
METHODS: We conducted a cohort study of clinical-trial protocols that were approved by research ethics committees in the UK, Switzerland, Germany and Canada in 2012. We examined the use of multiple-testing procedures to control the overall type …
Authors
Odutayo A; Gryaznov D; Copsey B; Monk P; Speich B; Roberts C; Vadher K; Dutton P; Briel M; Hopewell S
Volume
49
Pagination
pp. 968-978
Publisher
Oxford University Press (OUP)
Publication Date
June 1, 2020
DOI
10.1093/ije/dyaa026
Conference proceedings
International Journal of Epidemiology
Issue
3
ISSN
0300-5771