Journal article
Effectiveness of metformin to pregnant women with PCOS to reduce spontaneous abortion and gestational diabetes mellitus: a protocol for an overview of reviews
Abstract
INTRODUCTION: Polycystic ovary syndrome (PCOS) is a globally prevalent endocrinological disorder and has been associated with poor pregnancy outcomes, including a higher rate of gestational diabetes and miscarriage. Metformin is among the drugs investigated to improve the prognosis of pregnant women with PCOS.
OBJECTIVE: To conduct an overview of systematic reviews examining the effects of metformin versus placebo or no intervention throughout …
Authors
Nassif DS; Januário BL; Sousa BA; Thabane L; Abbade JF
Journal
BMJ Open, Vol. 14, No. 3,
Publisher
BMJ
Publication Date
March 2024
DOI
10.1136/bmjopen-2023-078217
ISSN
2044-6055