Journal article
Rationale and Design of a Large Study to Evaluate the Renal and Cardiovascular Effects of an ACE Inhibitor and Vitamin E in High-Risk Patients With Diabetes: The MICRO-HOPE Study
Abstract
OBJECTIVE: To describe the rationale and design of a large international study (microalbuminuria, cardiovascular, and renal outcomes [MICRO] in the HOPE [Heart Outcomes Prevention Evaluation] study) of an ACE inhibitor and vitamin E for the prevention of diabetic nephropathy (DN) and cardiovascular disease (CVD) in patients with diabetes and microalbuminuria (MA).
RESEARCH DESIGN AND METHODS: A total of 3,657 diabetic subjects, including 1,129 …
Authors
Gerstein HC; Bosch J; Pogue J; Taylor DW; Zinman B; Yusuf S; investigators THS
Journal
Diabetes Care, Vol. 19, No. 11, pp. 1225–1228
Publisher
American Diabetes Association
Publication Date
November 1, 1996
DOI
10.2337/diacare.19.11.1225
ISSN
0149-5992