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Optimization of biomolecule separation by...
Journal article

Optimization of biomolecule separation by combining microscale filtration and design‐of‐experiment methods

Abstract

There is considerable interest in developing microscale (i.e., high-throughput) methods that enable multiple filtration experiments to be run in parallel with smaller sample amounts and thus reduce the overall required time and associated cost to run the filtration tests. Previous studies to date have focused on simply evaluating the filtration capacity, not the separation performance. In this work, the stirred-well filtration (SWF) method was …

Authors

Kazemi AS; Kawka K; Latulippe DR

Journal

Biotechnology and Bioengineering, Vol. 113, No. 10, pp. 2131–2139

Publisher

Wiley

Publication Date

October 2016

DOI

10.1002/bit.25975

ISSN

0006-3592