Algorithm for predicting death among older adults in the home care setting: study protocol for the Risk Evaluation for Support: Predictions for Elder-life in the Community Tool (RESPECT) Journal Articles uri icon

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  • IntroductionOlder adults living in the community often have multiple, chronic conditions and functional impairments. A challenge for healthcare providers working in the community is the lack of a predictive tool that can be applied to the broad spectrum of mortality risks observed and may be used to inform care planning.ObjectiveTo predict survival time for older adults in the home care setting. The final mortality risk algorithm will be implemented as a web-based calculator that can be used by older adults needing care and by their caregivers.DesignOpen cohort study using the Resident Assessment Instrument for Home Care (RAI-HC) data in Ontario, Canada, from 1 January 2007 to 31 December 2013.ParticipantsThe derivation cohort will consist of āˆ¼437 000 older adults who had an RAI-HC assessment between 1 January 2007 and 31 December 2012. A split sample validation cohort will include āˆ¼122 000 older adults with an RAI-HC assessment between 1 January and 31 December 2013.Main outcome measuresPredicted survival from the time of an RAI-HC assessment. All deaths (nā‰ˆ245ā€…000) will be ascertained through linkage to a population-based registry that is maintained by the Ministry of Health in Ontario.Statistical analysisProportional hazards regression will be estimated after assessment of assumptions. Predictors will include sociodemographic factors, social support, health conditions, functional status, cognition, symptoms of decline and prior healthcare use. Model performance will be evaluated for 6-month and 12-month predicted risks, including measures of calibration (eg, calibration plots) and discrimination (eg, c-statistics). The final algorithm will use combined development and validation data.Ethics and disseminationResearch ethics approval has been granted by the Sunnybrook Health Sciences Centre Review Board. Findings will be disseminated through presentations at conferences and in peer-reviewed journals.Trial registration numberNCT02779309, Pre-results.


  • Hsu, Amy T
  • Manuel, Douglas G
  • Taljaard, Monica
  • Chalifoux, Mathieu
  • Bennett, Carol
  • Costa, Andrew
  • Bronskill, Susan
  • Kobewka, Daniel
  • Tanuseputro, Peter

publication date

  • December 2016