Journal article
The evolution of the randomized controlled trial and its role in evidence‐based decision making
Abstract
The randomized controlled trial has been used in medical research for a little over half a century. This manuscript provides an overview of some of the history and evolution of the randomized controlled trial during this period. There exists hierarchies of evidence for therapeutic, diagnostic and prognostic questions, and the randomized controlled trial is at the top of the therapeutic hierarchy. Despite being at the top of the therapeutic …
Authors
Devereaux PJ; Yusuf S
Journal
Journal of Internal Medicine, Vol. 254, No. 2, pp. 105–113
Publisher
Wiley
Publication Date
August 2003
DOI
10.1046/j.1365-2796.2003.01201.x
ISSN
0954-6820