Journal article
The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) Study Rationale and Design
Abstract
Although the beneficial effects of treatment with inhaled steroids in asthma are widely accepted, the role of early intervention in patients with mild asthma remains unsettled. Conventional efficacy trials are often of short duration and involve highly selected patient populations that exclude many patients typical of those encountered in routine clinical practice. Hence, a large "real-world" effectiveness study is needed to evaluate the …
Authors
Pauwels RA; Busse WW; O'Byrne PM; Pedersen S; Tan WC; Chen Y-Z; Ohlsson SV; Ullman A
Journal
Contemporary Clinical Trials, Vol. 22, No. 4, pp. 405–419
Publisher
Elsevier
Publication Date
August 2001
DOI
10.1016/s0197-2456(01)00144-1
ISSN
1551-7144
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Acute DiseaseAdministration, TopicalAdolescentAdultAnti-Inflammatory AgentsAsthmaBudesonideChildDouble-Blind MethodFollow-Up StudiesGlucocorticoidsHumansMiddle AgedMulticenter Studies as TopicNebulizers and VaporizersOutcome Assessment, Health CareRandom AllocationRandomized Controlled Trials as TopicResearch DesignRespiratory Function TestsSample SizeStatistics as Topic