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Edoxaban for treatment of venous thromboembolism...
Journal article

Edoxaban for treatment of venous thromboembolism in patients with cancer

Abstract

Direct oral anticoagulants may be effective and safe for treatment of venous thromboembolism (VTE) in cancer patients, but they have not been compared with low-molecular-weight heparin (LMWH), the current recommended treatment for these patients. The Hokusai VTE-cancer study is a randomised, open-label, clinical trial to evaluate whether edoxaban, an oral factor Xa inhibitor, is non-inferior to LMWH for treatment of VTE in patients with cancer. …

Authors

van Es N; Di Nisio M; Bleker SM; Segers A; Mercuri MF; Schwocho L; Kakkar A; Weitz JI; Beyer-Westendorf J; Boda Z

Journal

Thrombosis and Haemostasis, Vol. 114, No. 06, pp. 1268–1276

Publisher

Thieme

Publication Date

2015

DOI

10.1160/th15-06-0452

ISSN

0340-6245