Hypothermia Pediatric Head Injury Trial: The Value of a Pretrial Clinical Evaluation Phase Academic Article uri icon

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abstract

  • BACKGROUND: The utility of a pretrial clinical evaluation or run-in phase prior to conducting trials of complex interventions such as hypothermia therapy following severe traumatic brain injury in children and adolescents has not been established. METHODS: The primary objective of this study was to prospectively evaluate the ability of investigators to adhere to the clinical protocols of care including the cooling and rewarming procedures as well as management guidelines in patients with severe traumatic brain injury (Glasgow Coma Scale

authors

  • Hutchison, J
  • Ward, R
  • Lacroix, J
  • Hébert, P
  • Skippen, P
  • Barnes, M
  • Meyer, P
  • Morris, K
  • Kirpalani, Haresh
  • Singh, R
  • Dirks, P
  • Bohn, D
  • Moher, D

publication date

  • 2006

has subject area