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Data withdrawal in randomized controlled trials:...
Journal article

Data withdrawal in randomized controlled trials: Defining the problem and proposing solutions A commentary

Abstract

It is not uncommon for a participant to withdraw from a randomized controlled trial (RCT). The withdrawal of a participant results in missing data and the potential for withdrawal bias. Data withdrawal, or a request from a participant to withdraw all of their previously collected data from a study, is particularly problematic because it leaves little opportunity to characterize or statistically address those that have withdrawn to minimize …

Authors

Ye C; Giangregorio L; Holbrook A; Pullenayegum E; Goldsmith CH; Thabane L

Journal

Contemporary Clinical Trials, Vol. 32, No. 3, pp. 318–322

Publisher

Elsevier

Publication Date

May 2011

DOI

10.1016/j.cct.2011.01.016

ISSN

1551-7144