A practitioner's guide to developing critical appraisal skills What is the difference between clinical and statistical significance?

BACKGROUND: It is common to find published studies in which the authors claim to have found significant results. However, many times these results are only statistically significant with no meaningful impact in clinical settings. METHODS: The authors aim to clarify and differentiate the concepts of statistical and clinical significance, as well as to provide guidance on how to interpret research results to determine whether an observed …