Journal article
Assessing fragility of statistically significant findings from randomized controlled trials assessing pharmacological therapies for opioid use disorders: a systematic review
Abstract
BackgroundThe fragility index is a statistical measure of the robustness or “stability” of a statistically significant result. It has been adapted to assess the robustness of statistically significant outcomes from randomized controlled trials. By hypothetically switching some non-responders to responders, for instance, this metric measures how many individuals would need to have responded for a statistically significant finding to become …
Authors
Naji L; Dennis B; Rodrigues M; Bawor M; Hillmer A; Chawar C; Deck E; Worster A; Paul J; Thabane L
Journal
Trials, Vol. 25, No. 1,
Publisher
Springer Nature
DOI
10.1186/s13063-024-08104-x
ISSN
1468-6708