Endovascular therapy for advanced post-thrombotic syndrome: Proceedings from a multidisciplinary consensus panel Journal Articles uri icon

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  • Patients with advanced post-thrombotic syndrome (PTS) and chronic iliac vein obstruction suffer major physical limitations and impairment of health-related quality of life. Currently there is a lack of evidence-based treatment options for these patients. Early studies suggest that imaging-guided, catheter-based endovascular therapy can eliminate iliac vein obstruction and saphenous venous valvular reflux, resulting in reduced PTS severity; however, these observations have not been rigorously validated. A multidisciplinary expert panel meeting was convened to plan a multicenter randomized controlled clinical trial to evaluate endovascular therapy for the treatment of advanced PTS. This article summarizes the findings of the panel, and is expected to assist in developing a National Institutes of Health-sponsored clinical trial and other studies to improve the care of patients with advanced PTS.


  • Vedantham, Suresh
  • Kahn, Susan R
  • Goldhaber, Samuel Z
  • Comerota, Anthony J
  • Parpia, Sameer
  • Meleth, Sreelatha
  • Earp, Diane
  • Williams, Rick
  • Sista, Akhilesh K
  • Marston, William
  • Rathbun, Suman
  • Magnuson, Elizabeth A
  • Razavi, Mahmood K
  • Jaff, Michael R
  • Kearon, Clive

publication date

  • August 2016