Journal article
β-Blockers in sepsis: protocol for a systematic review and meta-analysis of randomised control trials
Abstract
INTRODUCTION: Sepsis is a common and deadly complication of infection. As part of the host response, sympathetic stimulation can result in septic myocardial depression, and metabolic, haematological and immunological dysfunction. Administration of β-blockers may attenuate this pathophysiological response to infection, but the effects on clinical outcomes are unknown. The objective of this systematic review is to determine the efficacy and …
Authors
Duan EH; Oczkowski SJW; Belley-Cote E; Whitlock R; Lamontagne F; Devereaux PJ; Cook DJ
Journal
BMJ Open, Vol. 6, No. 6,
Publisher
BMJ
Publication Date
June 2016
DOI
10.1136/bmjopen-2016-012466
ISSN
2044-6055