Journal article
Steroids and Spinal Cord Injury
Abstract
The National Acute Spinal Cord Injury Study (NASCIS) 2 and 3 trials are often cited as evidence that high-dose methylprednisolone is an efficacious intervention in the management of acute spinal cord injury. Neither of these studies convincingly demonstrate the benefit of steroids. There are concerns about the statistical analysis, randomization, and clinical end points. Even if the putative gains are statistically valid, the clinical benefits …
Authors
Nesathurai S
Journal
Journal of Trauma and Acute Care Surgery, Vol. 45, No. 6, pp. 1088–1093.
Publisher
Wolters Kluwer
Publication Date
December 1998
DOI
10.1097/00005373-199812000-00021
ISSN
2163-0755