Journal article
Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints
Abstract
Although cardiovascular disease is a major health burden for patients with chronic kidney disease, most cardiovascular outcome trials have excluded patients with advanced chronic kidney disease. Moreover, the major cardiovascular outcome trials that have been conducted in patients with end-stage renal disease have not demonstrated a treatment benefit. Thus, clinicians have limited evidence to guide the management of cardiovascular disease in …
Authors
Rossignol P; Agarwal R; Canaud B; Charney A; Chatellier G; Craig JC; Cushman WC; Gansevoort RT; Fellström B; Garza D
Journal
European Heart Journal, Vol. 40, No. 11, pp. 880–886
Publisher
Oxford University Press (OUP)
Publication Date
March 14, 2019
DOI
10.1093/eurheartj/ehx209
ISSN
0195-668X