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Journal article

Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic

Abstract

Importance: The COVID-19 pandemic created unprecedented challenges for clinical trials worldwide, threatening premature closure and trial integrity. Every phase of research operations was affected, often requiring modifications to protocol design and implementation. Objectives: To identify the barriers, solutions, and opportunities associated with continuing critical care trials that were interrupted during the pandemic, and to generate …

Authors

Cook D; Taneja S; Krewulak K; Zytaruk N; Menon K; Fowler R; Lamontagne F; Kho ME; Rochwerg B; Masse M-H

Journal

JAMA Network Open, Vol. 7, No. 7,

Publisher

American Medical Association (AMA)

Publication Date

July 1, 2024

DOI

10.1001/jamanetworkopen.2024.20458

ISSN

2574-3805