Genetic Vectors
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-Directed Cloning of Defined Large Regions from Bacterial Genomes: Identification of the
Sinorhizobium meliloti
pExo Megaplasmid Replicator Region Academic Article
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A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model Academic Article
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A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors Academic Article
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A Highly Efficient Molecular Cloning Platform that Utilises a Small Bacterial Toxin Gene Academic Article
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A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent Academic Article
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A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada Academic Article
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A Single Intramuscular Injection with an Adenovirus- Expressing IL-12 Protects BALB/c Mice Against Leishmania major Infection, While Treatment with an IL-4-Expressing Vector Increases Disease Susceptibility in B10.D2 Mice Academic Article
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A convenient plasmid system for construction of helper-dependent adenoviral vectors and its application for analysis of the breast-cancer-specific mammaglobin promoter Academic Article
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A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal Academic Article
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A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging Academic Article
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A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL. Academic Article
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A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity Academic Article
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A plasmid vehicle suitable for the molecular cloning and characterization of mammalian promoters Academic Article
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A role for GPx3 in activity of normal and leukemia stem cells Academic Article
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A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5 Academic Article
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A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus Academic Article
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AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma Academic Article
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ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING Academic Article
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Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque Academic Article
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Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector Academic Article
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Acoustic levitation as a screening method for excipient selection in the development of dry powder vaccines Academic Article
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Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases Academic Article
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Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity Academic Article
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Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial Academic Article
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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. Academic Article
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Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis Academic Article
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Adenoviral Transfer of the Murine Oncostatin M Gene Suppresses Dextran-Sodium Sulfate-Induced Colitis Academic Article
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Adenoviral Vector Expressing Murine Angiostatin Inhibits a Model of Breast Cancer Metastatic Growth in the Lungs of Mice Academic Article
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Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction Academic Article
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Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models Academic Article
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Adenoviral Vectors for Mucosal Vaccination Against Infectious Diseases Academic Article
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Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract. Academic Article
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Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung. Academic Article
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Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells Academic Article
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Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia Academic Article
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Adenoviral vectors: prospects for gene delivery to the central nervous system Academic Article
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Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat Academic Article
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Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4+, CD8+, and NK Cells Academic Article
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Adenoviral-mediated Gene Transfer to Mouse Salivary Glands Academic Article
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Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production Academic Article
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Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice Academic Article
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Adenovirus Vectors for Cytokine Gene Expression Conference Paper
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Adenovirus vectors for high-efficiency gene transfer into mammalian cells Academic Article
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Adenovirus vectors for human gene therapy Academic Article
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Adenovirus-Based Expression Vectors and Recombinant Vaccines Academic Article
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Adenovirus-Mediated Gene Transfer of TGF-β1 to the Renal Glomeruli Leads to Proteinuria Academic Article
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Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans Academic Article
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Adenovirus-Vector-Mediated Cytokine Gene Transfer to Lung Tissue Conference Paper
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Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung. Academic Article
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Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis Academic Article
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Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters Academic Article
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Adenovirus-mediated gene transfer of the proteoglycan biglycan induces fibroblastic responses in the lung. Academic Article
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Adenoviruses as expression vectors and recombinant vaccines Academic Article
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Adjunctive β2‐agonists reverse neuromuscular involvement in murine Pompe disease Academic Article
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Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons Academic Article
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An Enhanced System for Construction of Adenoviral Vectors by the Two-Plasmid Rescue Method Academic Article
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An Integrated Approach to Functional Genomics: Construction of a Novel Reporter Gene Fusion Library for
Sinorhizobium meliloti Academic Article
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An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity Academic Article
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An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene Academic Article
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An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Academic Article
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An efficient gene disruption system for the nematophagous fungus Purpureocillium lavendulum Academic Article
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An inducible mammalian amber suppressor: Propagation of a poliovirus mutant Academic Article
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Annexin-like alpha giardins: a new cytoskeletal gene family in Giardia lamblia Academic Article
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At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes Academic Article
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Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors Academic Article
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Autologous fibroblast implantation. Feasibility and potential problems in gene replacement therapy. Academic Article
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Autologous transplantation of canine long-term marrow culture cells genetically marked by retroviral vectors Academic Article
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BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis Academic Article
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Behavioral Effects of Infection with IL-6 Adenovector Academic Article
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Behavioral effects of infection with interferon-gamma adenovector Academic Article
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Bone Marrow-Derived Dendritic Cell Vaccination of Dogs with Naturally Occurring Melanoma by Using Human gp100 Antigen Academic Article
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CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX Academic Article
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Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseases Academic Article
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Characterization of Retroviral Gene Transfer into Highly Purified Human CD34− Cells with Primitive Hematopoietic Capacity Academic Article
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Characterization of a cryptic plasmid from Pseudomonas sp. and utilization of its temperature-sensitive derivatives for genetic manipulation Academic Article
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Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. Academic Article
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Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line Academic Article
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Cloning of the herpes simplex virus ICP4 Gene in an adenovirus vector: Effects on adenovirus gene expression and replication Academic Article
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Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer Academic Article
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Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity Academic Article
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Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy Academic Article
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Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer Academic Article
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Comparison of immune responses and protective efficacy of intranasal prime-boost immunization regimens using adenovirus-based and CpG/HH2 adjuvanted-subunit vaccines against genital Chlamydia muridarum infection Academic Article
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Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity Academic Article
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Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. Academic Article
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Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation Academic Article
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Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells Academic Article
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Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor Academic Article
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Construction of First-Generation Adenoviral Vectors Academic Article
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Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12 Academic Article
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Construction of a recombinant adenovirus for efficient delivery of the I-Scel yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeres Academic Article
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Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function. Academic Article
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Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation Conference Paper
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Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection Academic Article
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Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors Academic Article
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Cre Levels Limit Packaging Signal Excision Efficiency in the Cre/
loxP
Helper-Dependent Adenoviral Vector System Academic Article
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Customized Viral Immunotherapy for HPV-Associated Cancer Academic Article
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Cytotoxic T lymphocytes specific for herpes simplex virus (HSV) studied using adenovirus vectors expressing HSV glycoproteins Academic Article
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DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309 Academic Article
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Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time Academic Article
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Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses Academic Article
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Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination Academic Article
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Designer Sinorhizobium meliloti strains and multi-functional vectors enable direct inter-kingdom DNA transfer Academic Article
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DetailedAnalysis of the CD8
+
T-Cell Response followingAdenovirusVaccination Academic Article
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Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT Academic Article
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Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen Academic Article
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Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors Academic Article
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Development and use of a 293 cell line expressing lac repressor for the rescue of recombinant adenoviruses expressing high levels of rabies virus glycoprotein. Academic Article
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Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors Academic Article
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Development of a bovine adenovirus type 3-based expression vector Academic Article
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Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene Academic Article
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Development of a high-yield expression and purification system for platelet factor 4 Academic Article
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Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors Academic Article
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Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains Academic Article
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Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model Academic Article
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Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity Academic Article
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Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12 Academic Article
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Disparate Subcellular Localization Patterns of
Pseudomonas aeruginosa
Type IV Pilus ATPases Involved in Twitching Motility Academic Article
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Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents Academic Article
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Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors Academic Article
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Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells Academic Article
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Effects on brain tumor cell proliferation by an adenovirus vector that bears the Interleukin-4 gene Academic Article
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Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes. Academic Article
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Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance. Academic Article
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Eliminating Panglossian thinking in development of AAV therapeutics Academic Article
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Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines Academic Article
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Endogenous Granulocyte-Macrophage Colony-Stimulating Factor Overexpression In Vivo Results in the Long-Term Recruitment of a Distinct Dendritic Cell Population with Enhanced Immunostimulatory Function Academic Article
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Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes Academic Article
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Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor Academic Article
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Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2 Academic Article
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Enhanced Protection Against Fatal Mycobacterial Infection in SCID Beige Mice by Reshaping Innate Immunity with IFN-γ Transgene Academic Article
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Enhanced immunogenicity of BCG vaccine by using a viral-based GM-CSF transgene adjuvant formulation Academic Article
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Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine Academic Article
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Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGFβ1 Academic Article
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Eosinophilia is induced in the colon of Th2-sensitized mice upon exposure to locally expressed antigen Academic Article
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Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis Academic Article
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Evaluation of excipients for enhanced thermal stabilization of a human type 5 adenoviral vector through spray drying Academic Article
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Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity Academic Article
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Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis Academic Article
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Expression of Human Prohormone Convertase PC2 in a Baculovirus-Insect Cell System Academic Article
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Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes Academic Article
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Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging Academic Article
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Expression of the Glycoprotein of Vesicular Stomatitis Virus by Infectious Adenovirus Vectors Academic Article
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Expression of the HSV-2 ribonucleotide reductase subunits in adenovirus vectors or stably transformed cells: Restoration of enzymatic activity by reassociation of enzyme subunits in the absence of other HSV proteins Academic Article
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Expression of the Th1 Chemokine IFN-γ-Inducible Protein 10 in the Airway Alters Mucosal Allergic Sensitization in Mice Academic Article
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Factors Determining Vesicular Lipid Mixing Induced by Shortened Constructs of Influenza Hemagglutinin Academic Article
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Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice Academic Article
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Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular targeting using adenovirus-mediated expression Academic Article
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Foreign Gene Expression by Human Adenovirus Type 5-Based Vectors Studied Using Firefly Luciferase and Bacterial β-Galactosidase Genes as Reporters Academic Article
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Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-γ-lactone oxidase Academic Article
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Fusion to Albumin as a Means to Slow the Clearance of Small Therapeutic Proteins Using the <I>Pichia pastoris</I> Expression System: A Case Study Academic Article
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GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis Academic Article
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GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. Academic Article
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Gene Therapy for Pulmonary Diseases Academic Article
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Gene Vectors for Cytokine Expression In Vivo Academic Article
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Gene targeting in mouse embryonic stem cells with an adenoviral vector Academic Article
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Gene therapy for murine mucopolysaccharidosis type VII Conference Paper
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Generation of experimental allergic airways inflammation in the absence of draining lymph nodes Academic Article
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Genetic Manipulation of Human Embryonic Stem Cells: A System to Study Early Human Development and Potential Therapeutic Applications Academic Article
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Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines. Academic Article
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Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity Academic Article
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Getting oncolytic virus therapies off the ground Academic Article
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Goats Primed with Mycobacterium bovis BCG and Boosted with a Recombinant Adenovirus Expressing Ag85A Show Enhanced Protection against Tuberculosis Academic Article
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Going viral with cancer immunotherapy Academic Article
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Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene-deficient mice Academic Article
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Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells Academic Article
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Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A Academic Article
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Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons Academic Article
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Herpes Simplex Virus (HSV) Glycoproteins B and K Inhibit Cell Fusion Induced by HSV Syncytial Mutants Academic Article
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Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms Academic Article
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Herpes simplex virus IgG Fc receptors induced using recombinant adenovirus vectors expressing glycoproteins E and I Academic Article
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Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells Academic Article
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Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine Academic Article
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Heterologous boost vaccines for bacillus Calmette-Guérin prime immunization against tuberculosis. Academic Article
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High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα1-Antitrypsin with Negligible Toxicity Academic Article
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High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase Academic Article
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High-dose chemotherapy augments the efficacy of recombinant adenovirus vaccines and improves the therapeutic outcome Academic Article
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Human Adenovirus Vectors for Gene Transfer into Mammalian Cells Academic Article
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Human adenovirus cloning vectors based on infectious bacterial plasmids Academic Article
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Human adenovirus type 5 vectors expressing rabies glycoprotein Academic Article
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Human type 5 adenovirus-based tuberculosis vaccine: is the respiratory route of delivery the future? Academic Article
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IL-12 gene therapy protects mice in lethal Klebsiella pneumonia. Academic Article
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IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion Academic Article
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IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness Academic Article
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Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Academic Article
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Identification of an immunodominant cytotoxic T-lymphocyte recognition site in glycoprotein B of herpes simplex virus by using recombinant adenovirus vectors and synthetic peptides Academic Article
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Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells Academic Article
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Immune response to HIV-1 gag antigens induced by recombinant adenovirus vectors in mice and rhesus macaque monkeys. Academic Article
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Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1 Academic Article
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Immunization Strategies Against Pulmonary Tuberculosis: Considerations of T Cell Geography Chapter
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Immunization With a Bivalent Adenovirus-vectored Tuberculosis Vaccine Provides Markedly Improved Protection Over Its Monovalent Counterpart Against Pulmonary Tuberculosis Academic Article
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Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy Academic Article
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Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors Academic Article
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Immunological considerations for COVID-19 vaccine strategies Academic Article
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Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer Academic Article
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Immunotherapy-induced CD8+ T Cells Instigate Immune Suppression in the Tumor Academic Article
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In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma Academic Article
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In Vivo Cloning Strategy for Rhizobium Plasmids Academic Article
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In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer Academic Article
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In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors. Academic Article
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Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair Academic Article
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Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein Academic Article
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Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12 Academic Article
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Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1 Academic Article
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Induction of an Immune Response to Transmissible Gastroenteritis Coronavirus Using Vectors with Enteric Tropism Academic Article
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Inflammatory Cytokines, Angiogenesis, and Fibrosis in the Rat Peritoneum Academic Article
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Insertional mutagenesis using a synthetic lac operator Academic Article
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Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Academic Article
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Interleukin 10 gene transfer prevents experimental colitis in rats Academic Article
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Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression Academic Article
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Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw Academic Article
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Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs Academic Article
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Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral
Mycobacterium bovis
BCG Immunization against Pulmonary Tuberculosis Academic Article
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Intranasal Mucosal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances the Protection of BCG-Primed Guinea Pigs against Pulmonary Tuberculosis Academic Article
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Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth Academic Article
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Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors Academic Article
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Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. Academic Article
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Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc Academic Article
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Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency Academic Article
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Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes Academic Article
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Largen: A Molecular Regulator of Mammalian Cell Size Control Academic Article
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Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung Academic Article
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Lentivirus-mediated gene therapy for Fabry disease Academic Article
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Life-long systemic protection in mice vaccinated with and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes Academic Article
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Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia Academic Article
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Luciferase Therapeutic Microcapsules for Gene Therapy Academic Article
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MOLECULAR AND PHARMACOLOGICAL CHARACTERISATION OF THE MSH-R ALLELES IN SWISS CATTLE BREEDS Conference Paper
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Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury Academic Article
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Maraba Virus as a Potent Oncolytic Vaccine Vector Academic Article
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Maraba virus-vectored cancer vaccines represent a safe and novel therapeutic option for cats Academic Article
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Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis Academic Article
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Measles Vaccines Designed for Enhanced CD8+ T Cell Activation Academic Article
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Methods for construction of adenovirus vectors Academic Article
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MicroRNA-145 Targeted Therapy Reduces Atherosclerosis Conference Paper
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Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules Academic Article
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Modulation of extracellular matrix using adenovirus vectors Academic Article
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Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts Academic Article
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Mouse hepatitis virus spike and nucleocapsid proteins expressed by adenovirus vectors protect mice against a lethal infection Academic Article
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Mucosal immunization with a recombinant adenovirus vector induces local and systemic immunity and protection from herpes simplex virus. Academic Article
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Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs Academic Article
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Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo Academic Article
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Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression. Academic Article
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Mutational analysis of the herpes simplex virus trans-inducing factor Vmw65 Academic Article
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Nervous system modification by transplants and gene transfer Academic Article
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NeuNAc Oxime: A Slow-Binding and Effectively Irreversible Inhibitor of the Sialic Acid Synthase NeuB Academic Article
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Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome) Conference Paper
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Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection Academic Article
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ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic Academic Article
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Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats Academic Article
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Oncolytic Viruses: Therapeutics With an Identity Crisis Academic Article
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One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection Academic Article
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Optimization of Spray Drying Conditions for Yield, Particle Size and Biological Activity of Thermally Stable Viral Vectors Academic Article
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Optimizing vaccine-induced CD8+T-cell immunity: focus on recombinant adenovirus vectors Academic Article
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Overexpression of MyoD-inducible lysosomal sialidase (neu1) inhibits myogenesis in C2C12 cells Academic Article
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Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung. Academic Article
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Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β Academic Article
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Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway: Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway Academic Article
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Overproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector Academic Article
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Packaging capacity and stability of human adenovirus type 5 vectors Academic Article
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Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Academic Article
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Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes. Academic Article
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Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin Academic Article
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Phage-Mediated Gene Therapy Academic Article
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Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression Academic Article
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Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells Academic Article
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Potential roles for p53 in nucleotide excision repair Academic Article
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Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination Academic Article
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Preparation of Helper-Dependent Adenoviral Vectors Academic Article
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Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro Academic Article
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Proinflammatory properties of IL-4 in the intestinal microenvironment Academic Article
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Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus Academic Article
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Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4 or -10 Academic Article
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Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein Academic Article
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Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing hsv glycoprotein B Academic Article
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Protein Kinase C-Epsilon Mediates Phorbol Ester-Induced Phosphorylation of Connexin-43 Conference Paper
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Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung Academic Article
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Pseudotyping of Glycoprotein D-Deficient Herpes Simplex Virus Type 1 with Vesicular Stomatitis Virus Glycoprotein G Enables Mutant Virus Attachment and Entry Academic Article
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Purification and characterization of human interleukin-1beta expressed in recombinant Escherichia coli Academic Article
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RNA-polymerase III-driven expression cassettes in human gene therapy. Academic Article
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RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity Academic Article
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Ras regulation of cyclin D1 promoter Academic Article
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Recent Advances in the Development of Adenovirus- and Poxvirus- Vectored Tuberculosis Vaccines Academic Article
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Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors Academic Article
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Recombinant Human Adenovirus with RatMIP-2Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain Academic Article
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Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery Academic Article
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Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity Academic Article
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Recombinant adenovirus vectors expressing interleukin-5 and -6 specifically enhance mucosal immunoglobulin A responses in the lung Academic Article
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Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer Academic Article
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Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells Academic Article
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Replication-Defective Adenovirus Infection Reduces
Helicobacter felis
Colonization in the Mouse in a Gamma Interferon- and Interleukin-12-Dependent Manner Academic Article
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Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers Academic Article
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Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. Academic Article
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Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2 Academic Article
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Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell-independent protective immunity Academic Article
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Restoration of Vitamin C Synthesis in Transgenic Gulo−/− Mice by Helper-Dependent Adenovirus-Based Expression of Gulonolactone Oxidase Academic Article
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Retroviral expression of MIR2 decreases both surface MHC class I and the alloimmune CTL response Academic Article
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Selective Inhibition of Inward Rectifier K
+
Channels (Kir2.1 or Kir2.2) Abolishes Protection by Ischemic Preconditioning in Rabbit Ventricular Cardiomyocytes Academic Article
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Semliki Forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunity Academic Article
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Sequence analysis of bovine adenovirus type 3 early region 3 and fibre protein genes Academic Article
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Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice Academic Article
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Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines Academic Article
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Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis Academic Article
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Single-Dose Mucosal Immunotherapy With Chimpanzee Adenovirus-Based Vaccine Accelerates Tuberculosis Disease Control and Limits Its Rebound After Antibiotic Cessation Academic Article
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Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector Academic Article
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Somatic cell hybridization of Roberts syndrome and normal human fibroblasts transfected with plasmids carrying dominant selection markers Academic Article
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Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung Academic Article
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Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector Academic Article
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Strategies to Enhance Viral Penetration of Solid Tumors Academic Article
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Superior Tissue-Specific Expression from Tyrosinase and Prostate-Specific Antigen Promoters/Enhancers in Helper-Dependent Compared with First-Generation Adenoviral Vectors Academic Article
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Suppression of immunological response against a novel gene product delivered by implants of genetically modified fibroblasts. Academic Article
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Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin Academic Article
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Sustained expression of coagulation factor IX by modified cord blood-derived mesenchymal stromal cells Academic Article
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Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing Academic Article
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Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2 Academic Article
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Synthesis and Processing of the Haemagglutinin--esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus Academic Article
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Synthesis of the herpes simplex virus type 1 trans-activator Vmw65 in insect cells using a baculovirus vector Academic Article
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T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice Academic Article
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T-cell immunity generated by recombinant adenovirus vaccines Academic Article
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TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis Academic Article
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Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia Academic Article
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The 1−127 HA2 Construct of Influenza Virus Hemagglutinin Induces Cell−Cell Hemifusion Academic Article
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The CD8+ T Cell Population Elicited by Recombinant Adenovirus Displays a Novel Partially Exhausted Phenotype Associated with Prolonged Antigen Presentation That Nonetheless Provides Long-Term Immunity Academic Article
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The Development of a Bacteriophage Expression Vector for Cloning Immunoglobulin Variable Region Genes from B-Cell Genomic DNAa Academic Article
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The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells Academic Article
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The effect of E1 mutations on biochemical transformation by an adenovirus carrying the herpes simplex virus thymidine kinase gene in region E3 Academic Article
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The efficacy of genetic vaccination is dependent upon the nature of the vector system and antigen Academic Article
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The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells Academic Article
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The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector Academic Article
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The use of adenoviral vectors for gene therapy and gene transfer in vivo Academic Article
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Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. Academic Article
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Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes. Academic Article
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Towards gene therapy in the nervous system. Academic Article
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Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector Academic Article
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Transduction of Human Bone Marrow by Adenoviral Vector Academic Article
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Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts Academic Article
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Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. Academic Article
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Transgenic expression of granulocyte-macrophage colony-stimulating factor induces the differentiation and activation of a novel dendritic cell population in the lung Academic Article
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Transient Gene Transfer and Expression in the Lung Academic Article
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Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis Academic Article
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Transient Gene Transfer of Non-ELR Chemokines to Rodent Lung Induces Mononuclear Cell Accumulation and Activation Academic Article
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Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis Academic Article
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Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: inhibition of interferon-γ and immunoglobin G Academic Article
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Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection Academic Article
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Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice Academic Article
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Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2′-O-Methyl-RNA Academic Article
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Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma Academic Article
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Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus Academic Article
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Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα Academic Article
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Tumour therapy in mice using adenovirus vectors expressing human TNFa. Academic Article
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UV-enhanced reactivation of a UV-damaged reporter gene suggests transcription-coupled repair is UV-inducible in human cells Academic Article
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Use of Human Adenovirus-based Vectors for Antigen Expression in Animals Academic Article
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Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors Academic Article
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Use of a murine secreted alkaline phosphatase as a non-immunogenic reporter gene in mice Academic Article
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Use of differential fluorescence induction and optical trapping to isolate environmentally induced genes Academic Article
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Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration Academic Article
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Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization Conference Paper
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Vector-Derived Expression of Recombinant Rat Interleukin-6 Academic Article
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Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus Academic Article
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Vesicular stomatitis virus: re-inventing the bullet Academic Article
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Viral Booster Vaccines Improve
Mycobacterium bovis
BCG-Induced Protection against Bovine Tuberculosis Academic Article
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Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes Academic Article
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Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene Academic Article
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Yeast Recombinase FLP Functions Effectively in Human Cells for Construction of Adenovirus Vectors Academic Article
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[Ad hTRP2 - mediated immunity against melanoma is enhanced by dendritic cells pulsed with peptide]. Academic Article
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[Xenogeneic melanoma-related antigen elicits anti-tumor immune response, companied by autoimmune injury]. Academic Article