Genetic Vectors Concept

subject area of

• oriT -Directed Cloning of Defined Large Regions from Bacterial Genomes: Identification of the Sinorhizobium meliloti pExo Megaplasmid Replicator Region  Academic Article
• A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model  Academic Article
• A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors  Academic Article
• A Highly Efficient Molecular Cloning Platform that Utilises a Small Bacterial Toxin Gene  Academic Article
• A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent  Academic Article
• A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada  Academic Article
• A Single Intramuscular Injection with an Adenovirus- Expressing IL-12 Protects BALB/c Mice Against Leishmania major Infection, While Treatment with an IL-4-Expressing Vector Increases Disease Susceptibility in B10.D2 Mice  Academic Article
• A convenient plasmid system for construction of helper-dependent adenoviral vectors and its application for analysis of the breast-cancer-specific mammaglobin promoter  Academic Article
• A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal  Academic Article
• A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging  Academic Article
• A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL.  Academic Article
• A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity  Academic Article
• A plasmid vehicle suitable for the molecular cloning and characterization of mammalian promoters  Academic Article
• A role for GPx3 in activity of normal and leukemia stem cells  Academic Article
• A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5  Academic Article
• A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus  Academic Article
• AAV-mediated expression of 3TSR inhibits tumor and metastatic lesion development and extends survival in a murine model of epithelial ovarian carcinoma  Academic Article
• ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING  Academic Article
• Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque  Academic Article
• Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector  Academic Article
• Acoustic levitation as a screening method for excipient selection in the development of dry powder vaccines  Academic Article
• Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases  Academic Article
• Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity  Academic Article
• Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial  Academic Article
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.  Academic Article
• Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis  Academic Article
• Adenoviral Transfer of the Murine Oncostatin M Gene Suppresses Dextran-Sodium Sulfate-Induced Colitis  Academic Article
• Adenoviral Vector Expressing Murine Angiostatin Inhibits a Model of Breast Cancer Metastatic Growth in the Lungs of Mice  Academic Article
• Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction  Academic Article
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Academic Article
• Adenoviral Vectors for Mucosal Vaccination Against Infectious Diseases  Academic Article
• Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.  Academic Article
• Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung.  Academic Article
• Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells  Academic Article
• Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia  Academic Article
• Adenoviral vectors: prospects for gene delivery to the central nervous system  Academic Article
• Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat  Academic Article
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Academic Article
• Adenoviral-mediated Gene Transfer to Mouse Salivary Glands  Academic Article
• Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production  Academic Article
• Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice  Academic Article
• Adenovirus Vectors for Cytokine Gene Expression  Conference Paper
• Adenovirus vectors for high-efficiency gene transfer into mammalian cells  Academic Article
• Adenovirus vectors for human gene therapy  Academic Article
• Adenovirus-Based Expression Vectors and Recombinant Vaccines  Academic Article
• Adenovirus-Mediated Gene Transfer of TGF-β1 to the Renal Glomeruli Leads to Proteinuria  Academic Article
• Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans  Academic Article
• Adenovirus-Vector-Mediated Cytokine Gene Transfer to Lung Tissue  Conference Paper
• Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.  Academic Article
• Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis  Academic Article
• Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters  Academic Article
• Adenovirus-mediated gene transfer of the proteoglycan biglycan induces fibroblastic responses in the lung.  Academic Article
• Adenoviruses as expression vectors and recombinant vaccines  Academic Article
• Adjunctive β2‐agonists reverse neuromuscular involvement in murine Pompe disease  Academic Article
• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons  Academic Article
• An Enhanced System for Construction of Adenoviral Vectors by the Two-Plasmid Rescue Method  Academic Article
• An Integrated Approach to Functional Genomics: Construction of a Novel Reporter Gene Fusion Library for Sinorhizobium meliloti  Academic Article
• An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity  Academic Article
• An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene  Academic Article
• An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.  Academic Article
• An efficient gene disruption system for the nematophagous fungus Purpureocillium lavendulum  Academic Article
• An inducible mammalian amber suppressor: Propagation of a poliovirus mutant  Academic Article
• Annexin-like alpha giardins: a new cytoskeletal gene family in Giardia lamblia  Academic Article
• At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes  Academic Article
• Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors  Academic Article
• Autologous fibroblast implantation. Feasibility and potential problems in gene replacement therapy.  Academic Article
• Autologous transplantation of canine long-term marrow culture cells genetically marked by retroviral vectors  Academic Article
• BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis  Academic Article
• Behavioral Effects of Infection with IL-6 Adenovector  Academic Article
• Behavioral effects of infection with interferon-gamma adenovector  Academic Article
• Bone Marrow-Derived Dendritic Cell Vaccination of Dogs with Naturally Occurring Melanoma by Using Human gp100 Antigen  Academic Article
• CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX  Academic Article
• Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseases  Academic Article
• Characterization of Retroviral Gene Transfer into Highly Purified Human CD34− Cells with Primitive Hematopoietic Capacity  Academic Article
• Characterization of a cryptic plasmid from Pseudomonas sp. and utilization of its temperature-sensitive derivatives for genetic manipulation  Academic Article
• Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.  Academic Article
• Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line  Academic Article
• Cloning of the herpes simplex virus ICP4 Gene in an adenovirus vector: Effects on adenovirus gene expression and replication  Academic Article
• Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer  Academic Article
• Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity  Academic Article
• Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy  Academic Article
• Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer  Academic Article
• Comparison of immune responses and protective efficacy of intranasal prime-boost immunization regimens using adenovirus-based and CpG/HH2 adjuvanted-subunit vaccines against genital Chlamydia muridarum infection  Academic Article
• Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity  Academic Article
• Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors.  Academic Article
• Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation  Academic Article
• Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells  Academic Article
• Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor  Academic Article
• Construction of First-Generation Adenoviral Vectors  Academic Article
• Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12  Academic Article
• Construction of a recombinant adenovirus for efficient delivery of the I-Scel yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeres  Academic Article
• Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function.  Academic Article
• Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation  Conference Paper
• Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection  Academic Article
• Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors  Academic Article
• Cre Levels Limit Packaging Signal Excision Efficiency in the Cre/ loxP Helper-Dependent Adenoviral Vector System  Academic Article
• Customized Viral Immunotherapy for HPV-Associated Cancer  Academic Article
• Cytotoxic T lymphocytes specific for herpes simplex virus (HSV) studied using adenovirus vectors expressing HSV glycoproteins  Academic Article
• DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309  Academic Article
• Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time  Academic Article
• Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses  Academic Article
• Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination  Academic Article
• Designer Sinorhizobium meliloti strains and multi-functional vectors enable direct inter-kingdom DNA transfer  Academic Article
• DetailedAnalysis of the CD8 ⁺ T-Cell Response followingAdenovirusVaccination  Academic Article
• Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT  Academic Article
• Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen  Academic Article
• Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors  Academic Article
• Development and use of a 293 cell line expressing lac repressor for the rescue of recombinant adenoviruses expressing high levels of rabies virus glycoprotein.  Academic Article
• Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors  Academic Article
• Development of a bovine adenovirus type 3-based expression vector  Academic Article
• Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene  Academic Article
• Development of a high-yield expression and purification system for platelet factor 4  Academic Article
• Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors  Academic Article
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Academic Article
• Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model  Academic Article
• Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity  Academic Article
• Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12  Academic Article
• Disparate Subcellular Localization Patterns of Pseudomonas aeruginosa Type IV Pilus ATPases Involved in Twitching Motility  Academic Article
• Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents  Academic Article
• Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors  Academic Article
• Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells  Academic Article
• Effects on brain tumor cell proliferation by an adenovirus vector that bears the Interleukin-4 gene  Academic Article
• Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.  Academic Article
• Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance.  Academic Article
• Eliminating Panglossian thinking in development of AAV therapeutics  Academic Article
• Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines  Academic Article
• Endogenous Granulocyte-Macrophage Colony-Stimulating Factor Overexpression In Vivo Results in the Long-Term Recruitment of a Distinct Dendritic Cell Population with Enhanced Immunostimulatory Function  Academic Article
• Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes  Academic Article
• Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor  Academic Article
• Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2  Academic Article
• Enhanced Protection Against Fatal Mycobacterial Infection in SCID Beige Mice by Reshaping Innate Immunity with IFN-γ Transgene  Academic Article
• Enhanced immunogenicity of BCG vaccine by using a viral-based GM-CSF transgene adjuvant formulation  Academic Article
• Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine  Academic Article
• Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGFβ1  Academic Article
• Eosinophilia is induced in the colon of Th2-sensitized mice upon exposure to locally expressed antigen  Academic Article
• Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis  Academic Article
• Evaluation of excipients for enhanced thermal stabilization of a human type 5 adenoviral vector through spray drying  Academic Article
• Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity  Academic Article
• Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis  Academic Article
• Expression of Human Prohormone Convertase PC2 in a Baculovirus-Insect Cell System  Academic Article
• Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes  Academic Article
• Expression of exogenous wt-p53 does not affect normal hematopoiesis: implications for bone marrow purging  Academic Article
• Expression of the Glycoprotein of Vesicular Stomatitis Virus by Infectious Adenovirus Vectors  Academic Article
• Expression of the HSV-2 ribonucleotide reductase subunits in adenovirus vectors or stably transformed cells: Restoration of enzymatic activity by reassociation of enzyme subunits in the absence of other HSV proteins  Academic Article
• Expression of the Th1 Chemokine IFN-γ-Inducible Protein 10 in the Airway Alters Mucosal Allergic Sensitization in Mice  Academic Article
• Factors Determining Vesicular Lipid Mixing Induced by Shortened Constructs of Influenza Hemagglutinin  Academic Article
• Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice  Academic Article
• Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular targeting using adenovirus-mediated expression  Academic Article
• Foreign Gene Expression by Human Adenovirus Type 5-Based Vectors Studied Using Firefly Luciferase and Bacterial β-Galactosidase Genes as Reporters  Academic Article
• Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-γ-lactone oxidase  Academic Article
• Fusion to Albumin as a Means to Slow the Clearance of Small Therapeutic Proteins Using the <I>Pichia pastoris</I> Expression System: A Case Study  Academic Article
• GM-CSF Transgene-Based Adjuvant Allows the Establishment of Protective Mucosal Immunity Following Vaccination with Inactivated Chlamydia trachomatis  Academic Article
• GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.  Academic Article
• Gene Therapy for Pulmonary Diseases  Academic Article
• Gene Vectors for Cytokine Expression In Vivo  Academic Article
• Gene targeting in mouse embryonic stem cells with an adenoviral vector  Academic Article
• Gene therapy for murine mucopolysaccharidosis type VII  Conference Paper
• Generation of experimental allergic airways inflammation in the absence of draining lymph nodes  Academic Article
• Genetic Manipulation of Human Embryonic Stem Cells: A System to Study Early Human Development and Potential Therapeutic Applications  Academic Article
• Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.  Academic Article
• Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity  Academic Article
• Getting oncolytic virus therapies off the ground  Academic Article
• Goats Primed with Mycobacterium bovis BCG and Boosted with a Recombinant Adenovirus Expressing Ag85A Show Enhanced Protection against Tuberculosis  Academic Article
• Going viral with cancer immunotherapy  Academic Article
• Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene-deficient mice  Academic Article
• Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells  Academic Article
• Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A  Academic Article
• Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons  Academic Article
• Herpes Simplex Virus (HSV) Glycoproteins B and K Inhibit Cell Fusion Induced by HSV Syncytial Mutants  Academic Article
• Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms  Academic Article
• Herpes simplex virus IgG Fc receptors induced using recombinant adenovirus vectors expressing glycoproteins E and I  Academic Article
• Herpes simplex virus type-1 infection upregulates cellular promoters and telomerase activity in both tumor and nontumor human cells  Academic Article
• Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine  Academic Article
• Heterologous boost vaccines for bacillus Calmette-Guérin prime immunization against tuberculosis.  Academic Article
• High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα₁-Antitrypsin with Negligible Toxicity  Academic Article
• High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase  Academic Article
• High-dose chemotherapy augments the efficacy of recombinant adenovirus vaccines and improves the therapeutic outcome  Academic Article
• Human Adenovirus Vectors for Gene Transfer into Mammalian Cells  Academic Article
• Human adenovirus cloning vectors based on infectious bacterial plasmids  Academic Article
• Human adenovirus type 5 vectors expressing rabies glycoprotein  Academic Article
• Human type 5 adenovirus-based tuberculosis vaccine: is the respiratory route of delivery the future?  Academic Article
• IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.  Academic Article
• IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion  Academic Article
• IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness  Academic Article
• Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2)  Academic Article
• Identification of an immunodominant cytotoxic T-lymphocyte recognition site in glycoprotein B of herpes simplex virus by using recombinant adenovirus vectors and synthetic peptides  Academic Article
• Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells  Academic Article
• Immune response to HIV-1 gag antigens induced by recombinant adenovirus vectors in mice and rhesus macaque monkeys.  Academic Article
• Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1  Academic Article
• Immunization Strategies Against Pulmonary Tuberculosis: Considerations of T Cell Geography  Chapter
• Immunization With a Bivalent Adenovirus-vectored Tuberculosis Vaccine Provides Markedly Improved Protection Over Its Monovalent Counterpart Against Pulmonary Tuberculosis  Academic Article
• Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy  Academic Article
• Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors  Academic Article
• Immunological considerations for COVID-19 vaccine strategies  Academic Article
• Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer  Academic Article
• Immunotherapy-induced CD8+ T Cells Instigate Immune Suppression in the Tumor  Academic Article
• In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma  Academic Article
• In Vivo Cloning Strategy for Rhizobium Plasmids  Academic Article
• In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer  Academic Article
• In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors.  Academic Article
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Academic Article
• Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein  Academic Article
• Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12  Academic Article
• Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1  Academic Article
• Induction of an Immune Response to Transmissible Gastroenteritis Coronavirus Using Vectors with Enteric Tropism  Academic Article
• Inflammatory Cytokines, Angiogenesis, and Fibrosis in the Rat Peritoneum  Academic Article
• Insertional mutagenesis using a synthetic lac operator  Academic Article
• Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia  Academic Article
• Interleukin 10 gene transfer prevents experimental colitis in rats  Academic Article
• Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression  Academic Article
• Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw  Academic Article
• Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs  Academic Article
• Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral Mycobacterium bovis BCG Immunization against Pulmonary Tuberculosis  Academic Article
• Intranasal Mucosal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances the Protection of BCG-Primed Guinea Pigs against Pulmonary Tuberculosis  Academic Article
• Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth  Academic Article
• Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors  Academic Article
• Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model.  Academic Article
• Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc  Academic Article
• Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency  Academic Article
• Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes  Academic Article
• Largen: A Molecular Regulator of Mammalian Cell Size Control  Academic Article
• Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung  Academic Article
• Lentivirus-mediated gene therapy for Fabry disease  Academic Article
• Life-long systemic protection in mice vaccinated with and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes  Academic Article
• Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia  Academic Article
• Luciferase Therapeutic Microcapsules for Gene Therapy  Academic Article
• MOLECULAR AND PHARMACOLOGICAL CHARACTERISATION OF THE MSH-R ALLELES IN SWISS CATTLE BREEDS  Conference Paper
• Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury  Academic Article
• Maraba Virus as a Potent Oncolytic Vaccine Vector  Academic Article
• Maraba virus-vectored cancer vaccines represent a safe and novel therapeutic option for cats  Academic Article
• Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis  Academic Article
• Measles Vaccines Designed for Enhanced CD8+ T Cell Activation  Academic Article
• Methods for construction of adenovirus vectors  Academic Article
• MicroRNA-145 Targeted Therapy Reduces Atherosclerosis  Conference Paper
• Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules  Academic Article
• Modulation of extracellular matrix using adenovirus vectors  Academic Article
• Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts  Academic Article
• Mouse hepatitis virus spike and nucleocapsid proteins expressed by adenovirus vectors protect mice against a lethal infection  Academic Article
• Mucosal immunization with a recombinant adenovirus vector induces local and systemic immunity and protection from herpes simplex virus.  Academic Article
• Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs  Academic Article
• Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo  Academic Article
• Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression.  Academic Article
• Mutational analysis of the herpes simplex virus trans-inducing factor Vmw65  Academic Article
• Nervous system modification by transplants and gene transfer  Academic Article
• NeuNAc Oxime: A Slow-Binding and Effectively Irreversible Inhibitor of the Sialic Acid Synthase NeuB  Academic Article
• Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome)  Conference Paper
• Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection  Academic Article
• ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic  Academic Article
• Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats  Academic Article
• Oncolytic Viruses: Therapeutics With an Identity Crisis  Academic Article
• One-step preparation of gold nanovectors using folate modified polyethylenimine and their use in target-specific gene transfection  Academic Article
• Optimization of Spray Drying Conditions for Yield, Particle Size and Biological Activity of Thermally Stable Viral Vectors  Academic Article
• Optimizing vaccine-induced CD8⁺T-cell immunity: focus on recombinant adenovirus vectors  Academic Article
• Overexpression of MyoD-inducible lysosomal sialidase (neu1) inhibits myogenesis in C2C12 cells  Academic Article
• Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung.  Academic Article
• Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β  Academic Article
• Overexpression of the Endoplasmic Reticulum 60 Protein ER-60 Downregulates ApoB100 Secretion by Inducing Its Intracellular Degradation via a Nonproteasomal Pathway:  Evidence for an ER-60-Mediated and pCMB-Sensitive Intracellular Degradative Pathway  Academic Article
• Overproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector  Academic Article
• Packaging capacity and stability of human adenovirus type 5 vectors  Academic Article
• Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes  Academic Article
• Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes.  Academic Article
• Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin  Academic Article
• Phage-Mediated Gene Therapy  Academic Article
• Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression  Academic Article
• Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells  Academic Article
• Potential roles for p53 in nucleotide excision repair  Academic Article
• Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination  Academic Article
• Preparation of Helper-Dependent Adenoviral Vectors  Academic Article
• Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro  Academic Article
• Proinflammatory properties of IL-4 in the intestinal microenvironment  Academic Article
• Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus  Academic Article
• Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4 or -10  Academic Article
• Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein  Academic Article
• Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing hsv glycoprotein B  Academic Article
• Protein Kinase C-Epsilon Mediates Phorbol Ester-Induced Phosphorylation of Connexin-43  Conference Paper
• Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung  Academic Article
• Pseudotyping of Glycoprotein D-Deficient Herpes Simplex Virus Type 1 with Vesicular Stomatitis Virus Glycoprotein G Enables Mutant Virus Attachment and Entry  Academic Article
• Purification and characterization of human interleukin-1beta expressed in recombinant Escherichia coli  Academic Article
• RNA-polymerase III-driven expression cassettes in human gene therapy.  Academic Article
• RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity  Academic Article
• Ras regulation of cyclin D1 promoter  Academic Article
• Recent Advances in the Development of Adenovirus- and Poxvirus- Vectored Tuberculosis Vaccines  Academic Article
• Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors  Academic Article
• Recombinant Human Adenovirus with RatMIP-2Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain  Academic Article
• Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery  Academic Article
• Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity  Academic Article
• Recombinant adenovirus vectors expressing interleukin-5 and -6 specifically enhance mucosal immunoglobulin A responses in the lung  Academic Article
• Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer  Academic Article
• Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells  Academic Article
• Replication-Defective Adenovirus Infection Reduces Helicobacter felis Colonization in the Mouse in a Gamma Interferon- and Interleukin-12-Dependent Manner  Academic Article
• Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers  Academic Article
• Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.  Academic Article
• Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2  Academic Article
• Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell-independent protective immunity  Academic Article
• Restoration of Vitamin C Synthesis in Transgenic Gulo^−/− Mice by Helper-Dependent Adenovirus-Based Expression of Gulonolactone Oxidase  Academic Article
• Retroviral expression of MIR2 decreases both surface MHC class I and the alloimmune CTL response  Academic Article
• Selective Inhibition of Inward Rectifier K ⁺ Channels (Kir2.1 or Kir2.2) Abolishes Protection by Ischemic Preconditioning in Rabbit Ventricular Cardiomyocytes  Academic Article
• Semliki Forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunity  Academic Article
• Sequence analysis of bovine adenovirus type 3 early region 3 and fibre protein genes  Academic Article
• Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice  Academic Article
• Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines  Academic Article
• Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis  Academic Article
• Single-Dose Mucosal Immunotherapy With Chimpanzee Adenovirus-Based Vaccine Accelerates Tuberculosis Disease Control and Limits Its Rebound After Antibiotic Cessation  Academic Article
• Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector  Academic Article
• Somatic cell hybridization of Roberts syndrome and normal human fibroblasts transfected with plasmids carrying dominant selection markers  Academic Article
• Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung  Academic Article
• Stable transfer of a mouse dihydrofolate reductase gene into a deficient cell line using human adenovirus vector  Academic Article
• Strategies to Enhance Viral Penetration of Solid Tumors  Academic Article
• Superior Tissue-Specific Expression from Tyrosinase and Prostate-Specific Antigen Promoters/Enhancers in Helper-Dependent Compared with First-Generation Adenoviral Vectors  Academic Article
• Suppression of immunological response against a novel gene product delivered by implants of genetically modified fibroblasts.  Academic Article
• Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin  Academic Article
• Sustained expression of coagulation factor IX by modified cord blood-derived mesenchymal stromal cells  Academic Article
• Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing  Academic Article
• Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2  Academic Article
• Synthesis and Processing of the Haemagglutinin--esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus  Academic Article
• Synthesis of the herpes simplex virus type 1 trans-activator Vmw65 in insect cells using a baculovirus vector  Academic Article
• T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice  Academic Article
• T-cell immunity generated by recombinant adenovirus vaccines  Academic Article
• TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis  Academic Article
• Telomerase Mediates Vascular Endothelial Growth Factor-dependent Responsiveness in a Rat Model of Hind Limb Ischemia  Academic Article
• The 1−127 HA2 Construct of Influenza Virus Hemagglutinin Induces Cell−Cell Hemifusion  Academic Article
• The CD8+ T Cell Population Elicited by Recombinant Adenovirus Displays a Novel Partially Exhausted Phenotype Associated with Prolonged Antigen Presentation That Nonetheless Provides Long-Term Immunity  Academic Article
• The Development of a Bacteriophage Expression Vector for Cloning Immunoglobulin Variable Region Genes from B-Cell Genomic DNAa  Academic Article
• The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells  Academic Article
• The effect of E1 mutations on biochemical transformation by an adenovirus carrying the herpes simplex virus thymidine kinase gene in region E3  Academic Article
• The efficacy of genetic vaccination is dependent upon the nature of the vector system and antigen  Academic Article
• The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells  Academic Article
• The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector  Academic Article
• The use of adenoviral vectors for gene therapy and gene transfer in vivo  Academic Article
• Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.  Academic Article
• Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes.  Academic Article
• Towards gene therapy in the nervous system.  Academic Article
• Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector  Academic Article
• Transduction of Human Bone Marrow by Adenoviral Vector  Academic Article
• Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts  Academic Article
• Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.  Academic Article
• Transgenic expression of granulocyte-macrophage colony-stimulating factor induces the differentiation and activation of a novel dendritic cell population in the lung  Academic Article
• Transient Gene Transfer and Expression in the Lung  Academic Article
• Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis  Academic Article
• Transient Gene Transfer of Non-ELR Chemokines to Rodent Lung Induces Mononuclear Cell Accumulation and Activation  Academic Article
• Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis  Academic Article
• Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: inhibition of interferon-γ and immunoglobin G  Academic Article
• Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection  Academic Article
• Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice  Academic Article
• Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2′-O-Methyl-RNA  Academic Article
• Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma  Academic Article
• Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus  Academic Article
• Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα  Academic Article
• Tumour therapy in mice using adenovirus vectors expressing human TNFa.  Academic Article
• UV-enhanced reactivation of a UV-damaged reporter gene suggests transcription-coupled repair is UV-inducible in human cells  Academic Article
• Use of Human Adenovirus-based Vectors for Antigen Expression in Animals  Academic Article
• Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors  Academic Article
• Use of a murine secreted alkaline phosphatase as a non-immunogenic reporter gene in mice  Academic Article
• Use of differential fluorescence induction and optical trapping to isolate environmentally induced genes  Academic Article
• Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration  Academic Article
• Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization  Conference Paper
• Vector-Derived Expression of Recombinant Rat Interleukin-6  Academic Article
• Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus  Academic Article
• Vesicular stomatitis virus: re-inventing the bullet  Academic Article
• Viral Booster Vaccines Improve Mycobacterium bovis BCG-Induced Protection against Bovine Tuberculosis  Academic Article
• Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes  Academic Article
• Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene  Academic Article
• Yeast Recombinase FLP Functions Effectively in Human Cells for Construction of Adenovirus Vectors  Academic Article
• [Ad hTRP2 - mediated immunity against melanoma is enhanced by dendritic cells pulsed with peptide].  Academic Article
• [Xenogeneic melanoma-related antigen elicits anti-tumor immune response, companied by autoimmune injury].  Academic Article