Journal article
Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus
Abstract
The infection of epithelia] swine testicle and intestinal porcine epithelial (IPEC-1) cell lines by adenovirus type 5 (Ad5) has been studied in vitro by using an Ad5-luciferase recombinant containing the firefly luciferase gene as a reporter. Porcine cell lines supported Ad5 replication, showing virus titers, kinetics of virus production, and luciferase expression levels similar to those obtained in human 293 cells, which constitutively express …
Authors
Torres JM; Alonso C; Ortega A; Mittal S; Graham F; Enjuanes L
Journal
Journal of Virology, Vol. 70, No. 6, pp. 3770–3780
Publisher
American Society for Microbiology
Publication Date
June 1996
DOI
10.1128/jvi.70.6.3770-3780.1996
ISSN
0022-538X