Journal article
Behavioral Effects of Infection with IL-6 Adenovector
Abstract
The onset of autoimmunity in lupus-prone mice is accompanied by a constellation of behavioral deficits, termed Autoimmunity-Associated Behavioral Syndrome (AABS). In particular, a spontaneous increase in serum interleukin-6 (IL-6) levels in five-week old MRL-lpr mice coincides temporally with blunted responsiveness to sucrose and excessive immobility in the forced swim test. These relationships, along with evidence that sucrose intake drops …
Authors
Sakic B; Gauldie J; Denburg JA; Szechtman H
Journal
Brain Behavior and Immunity, Vol. 15, No. 1, pp. 25–42
Publisher
Elsevier
Publication Date
March 2001
DOI
10.1006/brbi.1999.0576
ISSN
0889-1591