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Cloning and Sequencing of the Cellular–Viral...
Journal article

Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line

Abstract

The human-viral junctions of integrated adenovirus type 5 (Ad5) DNA in 293 cells have been cloned and sequenced. The Ad5 sequences extend from nucleotides (nt) 1 to 4344 and are located in the pregnancy-specific beta-1-glycoprotein 4 (PSG 4) gene. This maps the insertion of Ad5 DNA to human chromosome 19 (19q13.2). The Ad5 sequences are represented as a single collinear insertion of viral DNA with no rearrangements. There were 19 bp of PSG4 DNA …

Authors

Louis N; Evelegh C; Graham FL

Journal

Virology, Vol. 233, No. 2, pp. 423–429

Publisher

Elsevier

Publication Date

July 1997

DOI

10.1006/viro.1997.8597

ISSN

0042-6822