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ADENOVIRUS-MEDIATED GENE TRANSFER IN THE...
Journal article

ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING

Abstract

Transplantation of genetically modified hepatocytes has been suggested as a therapeutic modality for impaired hepatocellular function. This study examined adenoviral-mediated gene transfer to isolated hepatocytes, under conditions mimicking clinical transplant preservation. Isolated rat hepatocytes were infected using replication-defective adenoviral vectors with an expression cassette containing the beta-galactosidase gene driven by a CMV …

Authors

CSETE ME; DRAZAN KE; VAN BREE M; MCINTEE DF; MCBRIDE WH; BETT A; GRAHAM FL; BUSUTTIL RW; BERK AJ; SHARED A

Journal

Transplantation, Vol. 57, No. 10, pp. 1502–1507

Publisher

Wolters Kluwer

Publication Date

5 1994

DOI

10.1097/00007890-199405270-00018

ISSN

0041-1337