Journal article
Cytotoxic T lymphocytes specific for herpes simplex virus (HSV) studied using adenovirus vectors expressing HSV glycoproteins
Abstract
In previous work, we observed that H-2k-restricted herpes simplex virus (HSV)-specific cytotoxic T lymphocytes (CTLs) were effectively able to lyse transfected target cells expressing HSV glycoprotein C (gC), but not cells expressing gB, gD or gE. To confirm and extend our observations on the specificity of anti-HSV CTLs, recombinant adenovirus (Ad) vectors able to express HSV-1 gB or gC (AdgB2 or AdgC) were constructed. Syngeneic target cells …
Authors
Witmer LA; Rosenthal KL; Graham FL; Friedman HM; Yee A; Johnson DC
Journal
Journal of General Virology, Vol. 71, No. 2, pp. 387–396
Publisher
Microbiology Society
Publication Date
February 1, 1990
DOI
10.1099/0022-1317-71-2-387
ISSN
0022-1317