Journal article
B7-1 gene transfer into human cancer cells by infection with an adenovirus-B7 (Ad-B7) expression vector
Abstract
Background: Transfection of the costimulatory molecule B7-1 into some murine tumors can increase antitumor immunity and eradicate tumor growth. The purpose of this work was to construct an adenovirus-B7 (Ad-B7) expression vector and study B7-1 gene transfer into human cancer cells.Methods: The human B7-1 cDNA was ligated into an expression cassette containing the human cytomegalovirus immediate early gene promoter and then inserted into the E1 …
Authors
Dessureault S; Graham F; Gallinger S
Journal
Annals of Surgical Oncology, Vol. 3, No. 3, pp. 317–324
Publisher
Springer Nature
Publication Date
5 1996
DOI
10.1007/bf02306289
ISSN
1068-9265