Journal article
High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase
Abstract
An adenovirus vector (AdCre1) expressing Cre recombinase has been used to induce recombination betweenloxP sites in human chromosomes. G418 resistant cells with oneloxP site, generated by transfection with a plasmid containingloxP between the SV40 promoter and the G418 resistance (neo) gene, were infected with AdCre1 and transfected with a plasmid containingloxP adjacent to a promoterless hisD gene. This resulted in integration of hisD …
Authors
Wang P; Anton M; Graham FL; Bacchetti S
Journal
Somatic Cell and Molecular Genetics, Vol. 21, No. 6, pp. 429–441
Publisher
Springer Nature
Publication Date
11 1995
DOI
10.1007/bf02310209
ISSN
0740-7750