Thrombin
Concept
Vocabulary Service
Overview
subject area of
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2 Mechanisms of action of low molecular weight heparins and heparinoids Academic Article
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A Barbourin-albumin Fusion Protein that Is Slowly Cleared In Vivo Retains the Ability to Inhibit Platelet Aggregation In Vitro Academic Article
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A Control Switch for Prothrombinase Academic Article
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A Graphene-Based Biosensing Platform Based on the Release of DNA Probes and Rolling Circle Amplification Academic Article
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A Protease TAMER: a nucleic acid-based anticoagulant Academic Article
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A Role for Pericellular Proteoglycan in the Binding of Thrombin or Antithrombin III by the Blood Vessel Endothelium? – The Effects of Proteoglycan-Degrading Enzymes and Glycosaminoglycan-Binding Proteins on 125I-Thrombin Binding by the Rabbit Thoracic Aorta In Vitro Academic Article
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A Significant Portion of the Aequorin Luminescent Signal from Stimulated Human and Rabbit Platelets is Due to Exposure of the Aequorin to Calcium in the Suspending Medium Academic Article
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A long-lasting, plasmin-activatable thrombin inhibitor aids clot lysis in vitro and does not promote bleeding in vivo Academic Article
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A novel approach to thrombin inhibition Academic Article
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A novel nucleotide-based thrombin inhibitor inhibits clot-bound thrombin and reduces arterial platelet thrombus formation Academic Article
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A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT) Academic Article
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A rationale for targeting antithrombotic therapy at the vessel wall: improved antithrombotic effect and decreased risk of bleeding. Academic Article
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A review of the oral direct thrombin inhibitor ximelagatran Academic Article
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A safety review of topical bovine thrombin-induced generation of antibodies to bovine proteins Academic Article
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A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery Academic Article
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A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V Academic Article
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A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation Academic Article
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A549 Lung Epithelial Cells Synthesize Anticoagulant Molecules on the Cell Surface and Matrix and in Conditioned Media Academic Article
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AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa Academic Article
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Accumulation of the inositol phosphates in thrombin-stimulated, washed rabbit platelets in the presence of lithium Academic Article
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Acquired free protein S deficiency is associated with antiphospholipid antibodies and increased thrombin generation in patients with systemic lupus erythematosus Academic Article
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Activation of blood coagulation by plaque rupture: Mechanisms and prevention Academic Article
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Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl Academic Article
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Activation of factor X and prothrombin in antithrombin-III depleted plasma: The effects of heparin Academic Article
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Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells Academic Article
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Active thrombin produced by the intestinal epithelium controls mucosal biofilms Academic Article
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Acute coronary syndromes: a focus on thrombin. Academic Article
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Acute in vitro effects of ethanol on responses of platelets from cholesterol-fed and Watanabe heritable hyperlipidemic rabbits. Academic Article
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Adenine nucleotides in thrombin-degranulated platelets: Effect of prolonged circulation in vivo Article
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Adjunctive Use of Direct Thrombin Inhibitors in Patients Receiving Fibrinolytic Therapy for Acute Myocardial Infarction Academic Article
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Adsorption of thrombin from buffer and modified plasma to polystyrene resins containing sulphonate and sulphamide arginyl methyl ester groups Academic Article
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Advances in the management of venous thromboembolism. Academic Article
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Affinity Analysis of a Protein−Aptamer Complex Using Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures Academic Article
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Age-related changes in factor VII proteolysisin vivo Academic Article
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Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor Academic Article
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Alpha-2-Macroglobulin Is an Important Progressive Inhibitor of Thrombin in Neonatal and Infant Plasma Academic Article
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Alpha-2-macroglobulin may provide protection from thromboembolic events in antithrombin III-deficient children Academic Article
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Altered inactivation of trinitrophenylated thrombin by antithrombin iii in the presence of heparin Academic Article
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Altering Heparin Cofactor II at VAL439 (P6) either Impairs Inhibition of Thrombin or Confers Elastase Resistance Academic Article
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Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function Academic Article
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An Approach to Assigning In Vitro Potency to Unfractionated and Low Molecular Weight Heparins Based on the Inhibition of Prothrombin Activation and Catalysis of Thrombin Inhibition Academic Article
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An Extensive Interaction Interface between Thrombin and Factor V Is Required for Factor V Activation Academic Article
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An Overview of the Heparin-Induced Thrombocytopenia Syndrome Academic Article
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An acquired factor V inhibitor associated with defective factor V function, storage and binding to multimerin 1 Academic Article
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An anticoagulant dermatan sulfate proteoglycan circulates in the pregnant woman and her fetus. Academic Article
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An overview of the mechanism of action of antithrombin and its inherited deficiency states Academic Article
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Analysis of Inhibition Rate Enhancement by Covalent Linkage of Antithrombin to Heparin as a Potential Predictor of Reaction Mechanism Academic Article
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Another oral thrombin inhibitor for stroke prevention in atrial fibrillation? Academic Article
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Anticoagulant Effects of Heparin in Neonatal Plasma' Academic Article
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Anticoagulant and Antithrombin Effects of Intimatan, a Heparin Cofactor II Agonist Academic Article
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Anticoagulants in heart disease: current status and perspectives Academic Article
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Antithrombin III Sudbury: An Ala384 → pro mutation with abnormal thrombin-binding activity and thrombotic diathesis Academic Article
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Antithrombin III-beta associates more readily than antithrombin III-alpha with uninjured and de-endothelialized aortic wall in vitro and in vivo. Academic Article
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Antithrombin-Heparin Covalent Complex Academic Article
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Antithrombin-III-Hamilton, Ala 382 to Thr: an antithrombin-III variant that acts as a substrate but not an inhibitor of alpha-thrombin and factor Xa Academic Article
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Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity Academic Article
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Antithrombin-III-Stockholm: a codon 392 (Gly----Asp) mutation with normal heparin binding and impaired serine protease reactivity Academic Article
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Antithrombotic Agents Academic Article
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Antithrombotic Properties of Heparin in a Neonatal Piglet Model of Thrombin-Induced Thrombosis Academic Article
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Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention Academic Article
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Application of Combinatorial Libraries and Protein Engineering to the Discovery of Novel Anti-Thrombotic Drugs Conference Paper
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Arachidonate induced fibrinogen binding to thrombin degranulated platelets is independent of released ADP Article
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Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein Academic Article
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Association of fibrinogen with human platelets pretreated with chymotrypsin or aggregated with ADP or thrombin: an immunocytochemical study Academic Article
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Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase Academic Article
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Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot Expansion to a Greater Extent than Thrombin Academic Article
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Benefit of Selective Factor Inhibition Academic Article
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Beyond Unfractionated Heparin and Warfarin Academic Article
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Binding of Aggregated Immunoglobulins to the Human Platelet Fc Receptors: A Mechanism of Platelet to Platelet Bridging Academic Article
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Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation Academic Article
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Biologic rationale for the therapeutic role of specific antithrombins Academic Article
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Biological Action of Colorless and Yellow Solutions of Gold Sodium Thiomalate on Thrombin Activity and the Mixed Lymphocyte Reaction Academic Article
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Bioregulatory roles for fibrin(ogen) on blood coagulation Academic Article
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Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex Academic Article
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Bivalirudin, thrombin and platelets: clinical implications and future directions. Academic Article
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Blood tests for the diagnosis of venous and arterial thrombosis. Academic Article
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Breast cancer chemotherapy induces the release of cell-free DNA, a novel procoagulant stimulus Academic Article
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By Increasing the Affinity of Heparin for Fibrin, Zn2+Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin Academic Article
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Carboxypeptidase B2 deficiency reveals opposite effects of complement C3a and C5a in a murine polymicrobial sepsis model Academic Article
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Cardiopulmonary Bypass Pumps and Thrombin Generation Academic Article
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Catalysis of Thrombin Inhibition Provides an Index for Estimating the Antithrombotic Potential of Glycosaminoglycans in Rabbits Academic Article
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Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity Academic Article
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Changes in the platelet phosphoinositides during the first minute after stimulation of washed rabbit platelets with thrombin Academic Article
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Characterization of the C-terminal Domain of a Potassium Channel from Streptomyces lividans (KcsA) Academic Article
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Chromatography of heparin on Sepharose–lysine: molecular size fractionation and its relevance to thrombin and antithrombin III binding Academic Article
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Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. Academic Article
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Coagulation Assays Academic Article
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Coagulation factor XIII and markers of thrombin generation and fibrinolysis in patients with inflammatory bowel disease Academic Article
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Comment: Treatment of Heparin-Induced Thrombocytopenia Academic Article
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Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development Academic Article
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Comparative behavior of thrombin and an inactive derivative, FPR-thrombin, toward the rabbit vascular endothelium. Heparin liberates FPR-thrombin from the endothelium in vivo. Academic Article
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Comparative effects of heparin and LMW heparin on hemostasis Conference Paper
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Comparative metabolism and distribution of rabbit heparin cofactor II and rabbit antithrombin in rabbits Academic Article
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Comparison of Heparin- and Dermatan Sulfate-mediated Catalysis of Thrombin Inactivation by Heparin Cofactor II Academic Article
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Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity☆ Academic Article
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Comparison of the Effects of Heparin and Hirudin on Thrombin Binding to the Normal and the De-Endothelialized Rabbit Aorta In Vitro Academic Article
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Comparison of the Proinflammatory and Procoagulant Properties of Nuclear, Mitochondrial, and Bacterial DNA Academic Article
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Comparison of the anticoagulant intensities of fondaparinux and enoxaparin in the organization to assess strategies in acute ischemic syndromes (OASIS)-5 trial Academic Article
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Comparison of three-factor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers Academic Article
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Conditions influencing platelet lysis Article
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Conformational Changes in Thrombin When Complexed by Serpins Academic Article
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Control Mechanisms in Thrombin Generation Academic Article
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Conversion of thrombin into an anticoagulant by protein engineering Academic Article
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Coordinate Activation of Human Platelet Protease-activated Receptor-1 and -4 in Response to Subnanomolar α-Thrombin Academic Article
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Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Academic Article
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Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery Academic Article
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Current anticoagulant therapy—unmet clinical needs Conference Paper
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Dabigatran Etexilate Academic Article
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Dabigatran Etexilate: Future Directions in Anticoagulant Treatment Academic Article
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Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function Academic Article
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Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction? Academic Article
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Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve‐Induced Thrombin Generation Academic Article
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Dabigatran monitoring made simple? Academic Article
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Decreased Concentrations of Heparinoids Are Required to Inhibit Thrombin Generation in Plasma from Newborns and Children Compared to Plasma from Adults due to Reduced Thrombin Potential Academic Article
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Decreased Thrombin Activity of Fibrin Clots Prepared in Cord Plasma Compared with Adult Plasma Academic Article
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Deendothelialization in vivo initiates a thrombogenic reaction at the rabbit aorta surface. Correlation of uptake of fibrinogen and antithrombin III with thrombin generation by the exposed subendothelium. Academic Article
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Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis Academic Article
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Deletion mutagenesis of heparin cofactor II: defining the minimum size of a thrombin inhibiting serpin Academic Article
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Detection of human fetal fibrinogen in umbilical cord plasma by parallel assays of immunoreactive and thrombin-clottable protein. Academic Article
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Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiency. Academic Article
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Development of antibodies to thrombin and factor V with recurrent bleeding in a patient exposed to topical bovine thrombin Academic Article
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Development of nonthrombogenicity of injured rabbit aortas despite inhibition of platelet adherence Article
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Developmental haemostasis Academic Article
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Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet-mediated events during thrombus formation Academic Article
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Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib Academic Article
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Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation Academic Article
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Direct Factor Xa and direct thrombin inhibitors: a clinical trial update. Academic Article
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Direct Thrombin Inhibitors in Acute Coronary Syndromes Academic Article
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Direct Thrombin Inhibitors in Cardiac Disease Academic Article
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Direct thrombin inhibitors Academic Article
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Direct thrombin inhibitors in acute coronary syndromes Academic Article
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Direct thrombin inhibitors in acute coronary syndromes: effect in patients undergoing early percutaneous coronary intervention Academic Article
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Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data Academic Article
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Displacement of Fibrin-bound Thrombin by r-Hirudin Precludes the Use of 131l-r-Hirudin for Detecting Pulmonary Emboli in the Rabbit Academic Article
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Disseminated Intravascular Coagulation [Abridged] Academic Article
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Dissociation of Thrombin's Substrate Interactions Using Site-Directed Mutagenesis Academic Article
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Divalent cations and the release reaction of pig platelets Academic Article
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Do Coagulation Screening Tests Detect Increased Generation of Thrombin and Plasmin in Sick Newborn Infants? Academic Article
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Does an enzyme other than thrombin contribute to unexpected changes in the levels of the different forms of thrombin activatable fibrinolysis inhibitor in patients with hemophilia A, hemophilia B and von Willebrand disease? Academic Article
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Drug Effects on Platelet Adherence to Collagen and Damaged Vessel Walls \textbar Request PDF Article
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EFFECT OF SERA ON THROMBIN ACTIVATION RATE CONSTANTS: A ONE-STAGE ASSAY OF THE EXTRINSIC SYSTEM Academic Article
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Early Intraplatelet Signaling Enhances the Release of Human Platelet PAR-1 and -4 Amino-Terminal Peptides in Response to Thrombin† Academic Article
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Effect of Covalent Serpin–Heparinoid Complexes on Plasma Thrombin Generation on Fetal Distal Lung Epithelium Academic Article
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Effect of Heparin Loading During Congenital Heart Operation on Thrombin Generation and Blood Loss Academic Article
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Effect of Nonspecific Binding to Plasma Proteins on the Antithrombin Activities of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Dermatan Sulfate Academic Article
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Effect of Repeated Treatment of Rabbit Platelets with Low Concentrations of Thrombin on their Function, Metabolism and Survival Academic Article
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Effect of Streptokinase on Hemostasis Academic Article
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Effect of a novel covalent antithrombin-heparin complex on thrombin generation on fetal distal lung epithelium Academic Article
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Effect of diet-induced hyperlipidemia on in vitro-function of rabbit platelets Article
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Effect of disease and chemotherapy on hemostasis in children with acute lymphoid leukemia. Academic Article
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Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system Academic Article
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Effect of heparins on thrombin generation in hemophilic plasma supplemented with FVIII, FVIIa, or FEIBA. Academic Article
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Effect of ionophore A23, 187 on thrombin-degranulated washed rabbit platelets Article
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Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro Academic Article
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Effects of Cathepsin G Pretreatment of Platelets on their Subsequent Responses to Aggregating Agents Academic Article
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Effects of Dermatan Sulfate and Heparin on Inhibition of Thrombus Growth in Vivo Academic Article
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Effects of Intermittent Pneumatic Calf Compression On Postoperative Thrombin and Plasmin Activity Academic Article
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Effects of external Ca2+ and Mg2+ on thrombin-induced changes in Ca2+ and Mg2+ of pig platelets Article
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Effects of heparin fractions of different affinities to antithrombin III and thrombin on the inactivation of thrombin and factor Xa by antithrombin III Academic Article
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Effects of sulfated polysaccharides on inhibition of thrombus formation initiated by different stimuli. Academic Article
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Effects on Thrombin Generation of Single Injections of Hirulog™ in Patients with Calf Vein Thrombosis Academic Article
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Elevated Fibrinopeptide A and B Levels during Thrombolytic Therapy: Real or Artefactual? Academic Article
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Enhanced binding of fibrinogen by the subendothelium after treatment of the rabbit aorta with thrombin. Academic Article
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Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents Academic Article
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Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin Academic Article
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Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Academic Article
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Evidence for thrombin binding to dermatan sulphate sites in the rabbit aorta subendothelium in vitro Academic Article
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Evolution of a highly functional circular DNA aptamer in serum Academic Article
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Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex Academic Article
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Exosite-interactive Regions in the A1 and A2 Domains of Factor VIII Facilitate Thrombin-catalyzed Cleavage of Heavy Chain Academic Article
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Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II Academic Article
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Expression in a cell-free system of normal and variant forms of human antithrombin III. Ability to bind heparin and react with alpha-thrombin Academic Article
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Expression screening of bacterial libraries of recombinant alpha-1 proteinase inhibitor variants for candidates with thrombin inhibitory capacity Academic Article
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Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood Academic Article
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Extracellular Histones Increase Tissue Factor Activity and Enhance Thrombin Generation by Human Blood Monocytes Academic Article
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Factor Xa and thrombin as targets for new oral anticoagulants Academic Article
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Factor Xa or thrombin: Is thrombin a better target? Conference Paper
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Factors responsible for ADP-induced release reaction of human platelets Article
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Familial thrombophilia and the prothrombin 20210A mutation Academic Article
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Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists Academic Article
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Fate of Thrombin and Thrombin-Antithrombin-III Complex Adsorbed to a Heparinized Biomaterial: Analysis of the Enzyme-Inhibitor Complexes Displaced by Plasma Academic Article
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Fibrin and Thrombin Sealants in Vascular and Cardiac Surgery: A Systematic Review and Meta-analysis Academic Article
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Fibrin moderates the catalytic action of heparin but not that of dermatan sulfate on thrombin inhibition in human plasma. Academic Article
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Fibrinogenolysis and thrombin generation after reduced dose bolus or conventional rt-PA for pulmonary embolism. The Coagulation Project Investigators of the Bolus Alteplase Pulmonary Embolism Group. Academic Article
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Fibrinolytic properties of lysine-derivatized polyethylene in contact with flowing whole blood (Chandler loop model) Academic Article
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Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Academic Article
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Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin Academic Article
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Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II: P1 Arg Is Required for Maximal Thrombin Inhibition Academic Article
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Functional Mapping of the Surface Residues of Human Thrombin Academic Article
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Further Studies on the Mechanisms for the Antithrombotic Effects of Sulfated Polysaccharides in Rabbits Academic Article
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Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Academic Article
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G-Protein–Coupled Receptors as Signaling Targets for Antiplatelet Therapy Academic Article
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Global haemostasis and point of care testing Academic Article
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Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors Academic Article
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HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase Academic Article
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HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions Academic Article
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HEPARIN-INDUCED THROMBOCYTOPENIA: A Ten-Year Retrospective Academic Article
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HUMAN PLATELET THROMBIN RECEPTORS Academic Article
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Hemophilia and von Willebrand's disease: 2. Management. Association of Hemophilia Clinic Directors of Canada. Academic Article
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Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways. Academic Article
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Heparan sulfate: Antithrombotic or not? Academic Article
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Heparin Cofactor II and Other Endogenous Factors in the Mediation of the Antithrombotic and Anticoagulant Effects of Heparin and Dermatan Sulfate Academic Article
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Heparin and Low Molecular Weight Heparins Inhibit Prothrombinase Formation but not its Activity in Plasma Academic Article
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Heparin binds to human monocytes and modulates their procoagulant activities and secretory phenotypes. Effects of histidine-rich glycoprotein Academic Article
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Heparin inhibits thrombin binding to rabbit thoracic aorta endothelium. Academic Article
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Heparin sensitivity and resistance in the neonate: An explanation Academic Article
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Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma Academic Article
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Heparin-Induced thrombocytopenia: IgG-Mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-Induced thrombocytopenia Academic Article
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Heparin-induced thrombocytopenia - therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes Academic Article
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Heparin-induced thrombocytopenia in intensive care patients Academic Article
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Heparin-induced thrombocytopenia in the critical care setting: Diagnosis and management^ Academic Article
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Heparin-induced thrombocytopenia: pathogenesis and management Academic Article
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Heparinless cardiopulmonary bypass revisited: A newer strategy to avoid heparin-related bleeding using dermatan sulfate Academic Article
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Heterotrimeric G-protein subunit Gα
i2
contributes to agonist-sensitive apoptosis and degranulation in murine platelets Academic Article
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High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13 Academic Article
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Hirulog in the Treatment of Unstable Angina Academic Article
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Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain Academic Article
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Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway Academic Article
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Histidine-rich glycoprotein is present in human platelets and is released following thrombin stimulation Academic Article
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Human platelets contain forms of factor V in disulfide-linkage with multimerin Academic Article
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Human tissue-type plasminogen activator releases fibrinopeptides A and B from fibrinogen. Academic Article
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Hypercoagulability after trauma: Hemostatic changes and relationship to venous thromboembolism Academic Article
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IMMUNOCYTOCHEMICAL LOCALIZATION OF FIBRINOGEN DURING THROMBIN-INDUCED AGGREGATION OF HUMAN PLATELETS Article
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IMPACT OF MUTATIONS AT THE P4 AND P5 POSITIONS ON THE REACTION OF ANTITHROMBIN WITH THROMBIN AND ELASTASE Academic Article
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INHIBITION OF THROMBIN BY HIRUDIN GENETICALLY FUSED TO WILD-TYPE OR MUTANT ANTITHROMBIN Academic Article
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Identification of Critical Residues on Thrombin Mediating Its Interaction with Fibrin Academic Article
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Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton Academic Article
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Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V Academic Article
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Immune Responses Associated With Perioperative Exposure and Reexposure to Topical Bovine Thrombin Do Not Impair Hemostasis Academic Article
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Immunological Consequences of Topical Bovine Thrombin Academic Article
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Impact of Chemotherapy on Thrombin Generation and on the Protein C Pathway in Breast Cancer Patients Academic Article
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In Vitro and in Vivo Functions of Thrombin-Treated Platelets \textbar Request PDF Academic Article
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In Vivo Clearance of Ternary Complexes of Vitronectin-Thrombin-Antithrombin Is Mediated by Hepatic Heparan Sulfate Proteoglycans Academic Article
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In VivoFormation of Protein Based Aqueous Microcompartments Academic Article
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In the Presence of Phospholipids, Glycosaminoglycans Potentiate Factor Xa-Mediated Protein C Activation by Modulating Factor Xa Activity† Academic Article
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In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits Academic Article
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In vivo behaviour of some antithrombin III-protease complexes. Academic Article
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In vivo photoactivation of caged thrombin. Academic Article
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Inactivation of thrombin by antithrombin III on a heparinized biomaterial Academic Article
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Increased sulphation improves the anticoagulant activities of heparan sulphate and dermatan sulphate Academic Article
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Increased thrombin generation and activity in patients with systemic lupus erythematosus and anticardiolipin antibodies: evidence for a prothrombotic state [see comments] Academic Article
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Influence of Mechanical Stretch on Thrombin Regulation by Fetal Mixed Lung Cells Academic Article
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Influence of activated factor VII concentrates on thrombin generation in full-term and preterm neonates Academic Article
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Influence of exogenous factor VIIa on thrombin generation in cord plasma of full-term and pre-term newborns Academic Article
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Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation Academic Article
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Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex Academic Article
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Inhibition of Thrombin by Antithrombin III and Heparin Cofactor II In Vivo Academic Article
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Inhibition of Thrombin-Neutralizing Activity of Antithrombin III by Steroid Hormones Academic Article
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Inhibition of factor X and factor V activation by dermatan sulfate and a pentasaccharide with high affinity for antithrombin III in human plasma Academic Article
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Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082 Academic Article
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Inhibition of platelet-dependent prothrombinase activity and thrombin generation by glycoprotein IIb/IIIa receptor-directed antagonists: potential contributing mechanism of benefit in acute coronary syndromes. Academic Article
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Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin Academic Article
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Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta Academic Article
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Inhibition of thrombin generation by simvastatin and lack of additive effects of aspirin in patients with marked hypercholesterolemia Academic Article
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Injury Of Cultured Endothelial Cells By Thrombin-Stimulated Platelets Article
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Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome Academic Article
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Interactions of polylysine with platelets Article
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Interactions of thermally denatured fibrinogen on polyethylene with plasma proteins and platelets Academic Article
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Intravascular Haemolysis with Experimentally Produced Vascular Thrombi Academic Article
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Investigation of the Anticoagulant Mechanisms of a Covalent Antithrombin-Heparin Complex Academic Article
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Investigation of the Mechanism of False Positive125I-Labelled Fibrinogen Scans Academic Article
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Kinetic Analysis of a Unique Direct Prothrombinase,fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity Academic Article
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Lack of Relationship Between Enhanced Bleeding Induced by Heparin and Other Sulfated Polysaccharides and Enhanced Catalysis of Thrombin Inhibition Academic Article
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Localization of fibrinogen during ADP- or thrombin-induced aggregation of washed rabbit platelets Academic Article
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Localization of the Thrombin-binding Domain on Prothrombin Fragment 2 Academic Article
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Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function Academic Article
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Lubricant‐Infused PET Grafts with Built‐In Biofunctional Nanoprobes Attenuate Thrombin Generation and Promote Targeted Binding of Cells Academic Article
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Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential Academic Article
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Management of Patients with Acute Coronary Syndromes Academic Article
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Mast Cell–Derived Exosomes Activate Endothelial Cells to Secrete Plasminogen Activator Inhibitor Type 1 Academic Article
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Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex Academic Article
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Mechanism of platelet shape change, aggregation, and release induced by collagen, thrombin, or A23,187 \textbar Request PDF Article
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Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex Academic Article
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Mechanisms for Inhibition of the Generation of Thrombin Activity by Sulfated Polysaccharides Academic Article
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Mechanisms for the anticoagulant effect of heparin and related polysaccharides. Academic Article
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Mechanisms of Action of Heparin: Applications to the Development of Derivatives of Heparin and Heparinoids with Antithrombotic Properties Academic Article
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Meeting the Unmet Needs in Anticoagulant Therapy Academic Article
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Microheterogeneity of antithrombin III: effect of single amino acid substitutions and relationship with functional abnormalities. Academic Article
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Modes and consequences of thrombin's interaction with fibrin Academic Article
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Modulation of Thrombin’s Procoagulant and Anticoagulant Properties Conference Paper
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Modulation of intrinsic prothrombin activation by fibrinogen and fibrin I. Academic Article
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Modulation of the Enzymatic Activity of α-Thrombin by Polyanions: Consequences on Intrinsic Activation of Factor V and Factor VIII Academic Article
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Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes Academic Article
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Molecular Basis for the Susceptibility of Fibrin-bound Thrombin to Inactivation by Heparin Cofactor II in the Presence of Dermatan Sulfate but Not Heparin Academic Article
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Molecular Mapping of the Thrombin-Heparin Cofactor II Complex Academic Article
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Molecular basis of inherited human antithrombin deficiency Academic Article
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Molecular cloning and expression of rabbit antithrombin III Academic Article
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Morphological analysis of microparticle generation in heparin-induced thrombocytopenia Academic Article
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Multicentric warfarin-induced skin necrosis complicating heparin-induced thrombocytopenia Academic Article
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Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation Academic Article
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NMR Structures Reveal How Oxidation Inactivates Thrombomodulin† Academic Article
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Neutralization of Enoxaparine-lnduced Bleeding by Protamine Sulfate Academic Article
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Neutrophil Extracellular Traps Promote Thrombin Generation Through Platelet-Dependent and Platelet-Independent Mechanisms Academic Article
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New Anticoagulant Strategies Academic Article
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New Anticoagulant Therapy Academic Article
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New Anticoagulants Academic Article
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New Antithrombotic Drugs Academic Article
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New Antithrombotics Academic Article
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New anticoagulant strategies. Academic Article
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New anticoagulants Conference Paper
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New aspects on treatment modalities for thromboembolic episodes Academic Article
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New developments in parenteral anticoagulation for arterial and venous thromboembolism Academic Article
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New method for packing the external auditory canal, middle ear space, and mastoid cavities after otologic surgery Academic Article
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New oral anticoagulants in atrial fibrillation Academic Article
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New oral anticoagulants in development Academic Article
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New oral anticoagulants: which one should my patient use? Academic Article
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New pharmacotherapy for stroke prevention in atrial fibrillation: Update 2010 Academic Article
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Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism Academic Article
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Novel anticoagulant agents: introduction Academic Article
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Novel paediatric anticoagulants: a review of the current literature Academic Article
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On the interaction of rabbit antithrombin III with the luminal surface of the normal and deendothelialized rabbit thoracic aorta in vitro Academic Article
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Only high levels of dabigatran attenuate catheter thrombosis in vitro and in rabbits Academic Article
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Orally Active Direct Thrombin Inhibitors Academic Article
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Organ Distribution of Fibrin in Disseminated Intravascular Coagulation Academic Article
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Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity Academic Article
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Parenteral Anticoagulants Academic Article
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Pathobiologic features and prevention of thrombotic complications associated with prosthetic heart valves: Fundamental principles and the contribution of platelets and thrombin Academic Article
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Pathways responsible for platelet hypersensitivity in rats with diabetes. I. Streptozocin-induced diabetes Article
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Pathways responsible for platelet hypersensitivity in rats with diabetes. II. Spontaneous diabetes in BB Wistar rats Article
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Peptide modified gold-coated polyurethanes as thrombin scavenging surfaces Academic Article
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Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin Academic Article
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Pharmacology and Clinical Potential of Direct Thrombin Inhibitors Academic Article
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Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin Academic Article
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Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass Academic Article
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Plasma Anticoagulant Mechanisms of Heparin, Heparan Sulfate, and Dermatan Sulfate Academic Article
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Plasma Thrombin Neutralization Assay: Pharmacokinetic Applications Academic Article
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Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets Academic Article
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Platelet Adherence to the Vessel Wall and to Collagen-Coated Surfaces \textbar Request PDF Article
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Platelet Interactions with the Endothelium and the Subendothelium: the Role of Thrombin and Prostacyclin Academic Article
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Platelet factor V New York: A defect in factor V distinct from that in factor V Quebec resulting in impaired prothrombinase generation Academic Article
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Platelet function and survival in rats with genetically determined hypercholesterolaemia Academic Article
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Platelet sialic acid and platelet survival after aggregation by ADP Article
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Polyphosphate binds with high affinity to exosite II of thrombin Academic Article
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Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial Academic Article
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Preclinical differentiation of low molecular weight heparins. Academic Article
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Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibition Academic Article
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Prevention of Thrombus Growth by Antithrombin III-Dependent and Two Direct Thrombin Inhibitors in Rabbits: Implications for Antithrombotic Therapy Academic Article
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Prevention of activation of blood coagulation during acute coronary ischemic syndromes beyond aspirin and heparin Academic Article
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Prevention of thrombus formation and growth by antithrombin III and heparin cofactor II-dependent thrombin inhibitors: Importance of heparin cofactor II Academic Article
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Proceedings: Inhibition of collagen- or thrombin-induced shape change of rabbit platelets Academic Article
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Prognostic utility and characterization of cell-free DNA in patients with severe sepsis Academic Article
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Prolonged Antithrombin Activity of Low-Molecular-Weight Heparins Academic Article
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Prolonged in vivo anticoagulant activity of a hirudin–albumin fusion protein secreted from Pichia pastoris Academic Article
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Protease activated receptors 1 and 4 govern the responses of human platelets to thrombin Academic Article
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Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activityin Vivo Academic Article
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Protein‐Mediated Suppression of Rolling Circle Amplification for Biosensing with an Aptamer‐Containing DNA Primer Academic Article
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Purification of silica‐free DNA and characterization of its role in coagulation Academic Article
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Quality Control Certification of RNA Aptamer-Based Detection Academic Article
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RESOLUTION OF ACUTE MASSIVE PULMONARY EMBOLISM AFTER PULMONARY ARTERIAL INFUSION OF STREPTOKINASE Academic Article
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Rabbit lung macrophages stimulate platelets in vitro as observed by density-gradient centrifugation and transmission electron microscopy Article
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Radiolabeled r-Hirudin as a Measure of Thrombin Activity at, or within, the Rabbit Aorta Wall In Vitro and In Vivo Academic Article
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Randomized phase 2 trial comparing
JNJ
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Reactions of 14C-ADP and 14C-ATP with washed platelets from rabbits Article
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Recurrence of Dialysis Shunt Pseudoaneurysm Following Percutaneous Thrombin Embolization Academic Article
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Reduced Plasminogen Binding and Delayed Activation Render γ′-Fibrin More Resistant to Lysis than γA-Fibrin Academic Article
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Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins Academic Article
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Regulation of Chemerin Bioactivity by Plasma Carboxypeptidase N, Carboxypeptidase B (Activated Thrombin-activable Fibrinolysis Inhibitor), and Platelets Academic Article
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Regulation of Tissue Inflammation by Thrombin-Activatable Carboxypeptidase B (or TAFI) Book
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Regulation of tissue inflammation by thrombin-activatable carboxypeptidase B (or TAFI) Academic Article
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Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates Academic Article
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Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III Academic Article
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Reversing anticoagulants both old and new. Academic Article
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Review: Laboratory markers quantifying prothrombin activation and actions of thrombin in venous and arterial thrombosis do not accurately assess disease severity or the effectiveness of treatment Academic Article
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Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve–Induced Thrombin Generation Academic Article
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Role of thrombospondin in platelet aggregation. Academic Article
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Roles of Low Specificity and Cofactor Interaction Sites on Thrombin during Factor XIII Activation Academic Article
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Roles of thrombin and platelet membrane glycoprotein IIb/IIIa in platelet-subendothelial deposition after angioplasty in an ex vivo whole artery model. Academic Article
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Safety and Efficacy of Thrombin-JMI: A Multidisciplinary Expert Group Consensus Academic Article
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Secondary Prevention of Venous Thromboembolism with the Oral Direct Thrombin Inhibitor Ximelagatran Academic Article
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Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics Academic Article
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Selective and Sustained Inhibition of Surface-bound Thrombin Activity by Intimatan/Heparin Cofactor II and Its Relevance to Assessing Systemic Anticoagulation In Vivo, Ex Vivo and In Vitro Academic Article
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Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders Academic Article
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Shortening of the Bleeding Time in Rabbits by Hydrocortisone Caused by Inhibition of Prostacyclin Generation by the Vessel Wall Academic Article
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Site-directed mutagenesis of the P2 residue of human antithrombin Academic Article
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Sodium arachidonate can induce platelet shape change and aggregation which are independent of the release reaction Academic Article
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State-of-the-Art-Review : Statins Induce Hypothrombotic States? Academic Article
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Statins and Thrombin Academic Article
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Strategies for development of novel antithrombotics: modulating thrombin's procoagulant and anticoagulant properties Academic Article
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Streptokinase and rt-PA activate platelets by a different way: implications on the rethrombosis rate after their administration in myocardial infarction. Academic Article
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Structural Effects of a Covalent Linkage Between Antithrombin and Heparin: Covalent N-Terminus Attachment of Heparin Enhances the Maintenance of Antithrombin's Activated State Academic Article
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Structural requirements for the activation of human factor VIII by thrombin Academic Article
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Structure-Switching Signaling Aptamers Academic Article
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Studies investigating platelet aggregation and release initiated by sera from patients with thrombotic thrombocytopenic purpura Academic Article
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Studies on the coagulant enzyme from Agkistrodon rhodostoma venom. Isolation and some properties of the enzyme Academic Article
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Surface modification with PEG and hirudin for protein resistance and thrombin neutralization in blood contact Academic Article
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Synergism between platelet aggregating agents: The role of the arachidonate pathway Academic Article
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Synthesis and radioiodination of a stannyl oligodeoxyribonucleotide Academic Article
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TAFIa (CPU) is generatedin vivoat levels that can substantially affect fibrinolysis in chimpanzees in response to thrombin generation Academic Article
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Targeting Tumor Vasculature With an Oncolytic Virus Academic Article
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Targeting complement component 5a promotes vascular integrity and limits airway remodeling Academic Article
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Thalidomide-prednisone maintenance following autologous stem cell transplant for Multiple Myeloma: effect on thrombin generation and procoagulant markers in NCIC CTG MY.10 Academic Article
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The Additive Effect of Low Molecular Weight Heparins on Thrombin Inhibition by Dermatan Sulfate Academic Article
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The Antithrombotic Properties of Human Prothrombin Fragment 1.2 in Mice Academic Article
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The Asp272–Glu282 Region of Platelet Glycoprotein Ibα Interacts with the Heparin-binding Site of α-Thrombin and Protects the Enzyme from the Heparin-catalyzed Inhibition by Antithrombin III Academic Article
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The Binding of Unfractionated Heparin and Low Molecular Weight Heparin to Thrombin-Activated Human Endothelial Cells Academic Article
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The Clearance of Thrombin-antithrombin and Related Serpin-enzyme Complexes from the Circulation: Role of Various Hepatocyte Receptors Academic Article
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The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System Academic Article
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The Coagulation System in Humans Academic Article
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The Effect of Antithrombin III-Independent Thrombin Inhibitors and Heparin on Fibrin Accretion onto Fibrin-Coated Polyethylene \textbar Request PDF Academic Article
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The Effect of Heparin Adsorbed on Sepharose-Lysine on the Inactivation of Thrombin by Anti-Thrombin III Academic Article
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The Effect of Pretreatment of Human or Rabbit Platelets With Chymotrypsin on Their Responses to Human Fibrinogen and Article
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The Effect of Thrombin Inhibitors on Tissue Plasminogen Activator Induced Thrombolysis in a Rat Model Academic Article
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The Effect of Thrombin on Platelet Accumulation on the Vessel Wall - Influence of Heparin and Aspirin Academic Article
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The Effects of Heparin and Annexin V on Fibrin Accretion after Injury in the Jugular Veins of Rabbits Academic Article
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The Effects of Hormone Replacement Therapy on Thrombin Generation, Fibrinolysis Inhibition, and Resistance to Activated Protein C Academic Article
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The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy Academic Article
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The King is Dead (Warfarin): Direct Thrombin and Factor Xa Inhibitors: The Next Diadochian War? Academic Article
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The Molecular Pathology of Inherited Human Antithrombin III Deficiency Academic Article
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The N-terminal domain of antithrombin-III is essential for heparin binding and complex-formation with, but not cleavage by, α-thrombin Academic Article
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The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations Academic Article
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The Oral Thrombin Inhibitor Dabigatran: Strengths and Weaknesses Academic Article
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The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia Academic Article
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The Pathophysiology of Heparin-Induced Thrombocytopenia Academic Article
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The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex Academic Article
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The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII Academic Article
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The Transferable Tail: Fusion of the N-Terminal Acidic Extension of Heparin Cofactor II to α1-Proteinase Inhibitor M358R Specifically Increases the Rate of Thrombin Inhibition† Academic Article
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The absence of `minor' risk factors for recurrent venous thromboembolism: a systematic review of negative predictive values and negative likelihood ratios Academic Article
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The affinity of human, rabbit and bovine thrombins for sepharose-lysine and other conjugates Academic Article
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The appended tail region of heparin cofactor II and additional reactive centre loop mutations combine to increase the reactivity and specificity of α1-proteinase inhibitor M358R for thrombin Academic Article
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The beginning of the end of warfarin? Academic Article
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The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model Academic Article
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The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem Academic Article
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The blood platelet as a model for regulating blood coagulation on cell surfaces and its consequences. Academic Article
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The chemotherapy metabolite acrolein upregulates thrombin generation and impairs the protein C anticoagulant pathway in animal-based and cell-based models Academic Article
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The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Academic Article
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The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation Academic Article
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The direct thrombin inhibitor hirudin Academic Article
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The discovery and characterization of a novel nucleotide-based thrombin inhibitor Academic Article
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The effect of aggregating agents on oxidative metabolism of rabbit platelets Article
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The effect of glucose on the platelet response to release-inducing stimuli Article
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The effect of prostaglandin E1 on platelet function in vitro and in vivo Academic Article
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The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces Academic Article
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The evolving role of direct thrombin inhibitors in acute coronary syndromes. Academic Article
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The hypercoagulable state in cancer patients Academic Article
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The hypersensitivity to thrombin of platelets from diabetic rats is not due to increased thrombin binding Academic Article
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The impact of the endothelial protein C receptor on thrombin generation and clot lysis Academic Article
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The importance of thrombin inhibition for the expression of the anticoagulant activities of heparin, dermatan sulphate, low molecular weight heparin and pentosan polysulphate Academic Article
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The inactivation of thrombin and plasmin by antithrombin III in the presence of Sepharose-heparin Academic Article
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The influence of heparin, NaCl and CaCl2 on the rate of the thrombin-antithrombin III reaction Academic Article
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The inhibition by heparin of the intrinsic pathway activation of factor X in the absence of antithrombin-III Academic Article
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The inhibition of the anticoagulant activity of heparin by platelets, brain phospholipids, and tissue factor Academic Article
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The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin Academic Article
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The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction Academic Article
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The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase Academic Article
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The plasma concentration of activated protein C appears normal in patients with haemophilia Academic Article
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The plasma proteases, thrombin and plasmin, degrade the proteoglycan of rabbit aorta segments in vitro: an integrated ultrastructural and biochemical study. Academic Article
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The presence of plasma proteins facilitates the uptake of 125I-thrombin by the rabbit thoracic aorta endothelium Academic Article
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The proteolytic action of Arvin on human fibrinogen Academic Article
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The relative importance of thrombin inhibition and factor Xa inhibition to the antithrombotic effects of heparin Academic Article
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The single-stranded DNA aptamer-binding site of human thrombin. Academic Article
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The status of new anticoagulants Academic Article
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The thrombogenicity of prothrombin complex concentrates: I. The relationship between characteristics and thrombogenicity in rabbits Academic Article
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Think of HIT Academic Article
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Thrombin Activatable Fibrinolysis Inhibitor, a Potential Regulator of Vascular Inflammation Academic Article
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Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ibα with Thrombin Anion-binding Exosites I and II, Respectively Academic Article
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Thrombin Binds to Soluble Fibrin Degradation Products Where it Is Protected From Inhibition by Heparin-Antithrombin but Susceptible to Inactivation by Antithrombin-Independent Inhibitors Academic Article
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Thrombin Cleavage of Osteopontin Disrupts a Pro-chemotactic Sequence for Dendritic Cells, Which Is Compensated by the Release of Its Pro-chemotactic C-terminal Fragment Academic Article
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Thrombin Generation Academic Article
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Thrombin Generation and Presence of Thrombin Receptor in Ovarian Follicles1 Academic Article
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Thrombin Generation during Cardiac Surgery: Is Heparin the Ideal Anticoagulant? Academic Article
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Thrombin Generation in Newborn Plasma Is Critically Dependent on the Concentration of Prothrombin Academic Article
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Thrombin Hydrolysis of Human Osteopontin Is Dependent on Thrombin Anion-binding Exosites Academic Article
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Thrombin Inhibition Is Impaired in Plasma of Sick Neonates Academic Article
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Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin Academic Article
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Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains Academic Article
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Thrombin Regulation in Children Differs from Adults in the Absence and Presence of Heparin Academic Article
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Thrombin Regulation in Mother and Fetus During Pregnancy Academic Article
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Thrombin activation rate constant: One-stage chromogenic assay for the extrinsic system Academic Article
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Thrombin and Antithrombotics Academic Article
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Thrombin as an adjuvant to reanastomosis of the fallopian tubes reduces implantations in the rabbit. Academic Article
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Thrombin binding to platelets and their activation in plasma Academic Article
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Thrombin binding to platelets from hypercholesterolaemic rats Academic Article
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Thrombin generation abnormalities in Quebec platelet disorder Academic Article
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Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes Academic Article
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Thrombin generation and fibrin formation following injury to rabbit neointima. Studies of vessel wall reactivity and platelet survival Article
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Thrombin generation in patients undergoing carotid endarterectomy: Implications in acute vessel wall closure and antithrombotic therapy Academic Article
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Thrombin generation, ProC(®)Global, prothrombin time and activated partial thromboplastin time in thawed plasma stored for seven days and after methylene blue/light pathogen inactivation. Academic Article
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Thrombin generationin vitroin the presence of by-passing agents in siblings with severe haemophilia A Academic Article
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Thrombin structure and function Academic Article
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Thrombin-activatable carboxypeptidase B cleavage of osteopontin regulates neutrophil survival and synoviocyte binding in rheumatoid arthritis Academic Article
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Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo Academic Article
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Thrombin-cleaved Fragments of Osteopontin Are Overexpressed in Malignant Glial Tumors and Provide a Molecular Niche with Survival Advantage Academic Article
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Thrombin-induced inositol phosphate production by platelets from rats with diet-induced or genetically determined hypercholesterolemia. Academic Article
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Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol Academic Article
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Thrombin-induced platelet membrane glycoprotein IIb and IIIa complex formation. An electron microscope study. Academic Article
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Thrombocytopenia in Preeclampsia and Eclampsia Academic Article
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Thrombocytopenia in septicemia: the role of disseminated intravascular coagulation Academic Article
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Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events Academic Article
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Thrombospondin is the endogenous lectin of human platelets Academic Article
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Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome Academic Article
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Thrombotic characteristics of extracellular vesicles derived from prostate cancer cells Academic Article
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Tissue factor microparticles and haemophilia Academic Article
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U73122 affects the equilibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets. Academic Article
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Uncontrolled PGI2 production by whole vessel wall segments due to thrombin generation and its prevention by heparin Academic Article
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Understanding Thrombin and Hemostasis Academic Article
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Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa Academic Article
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Uptake and Catabolism of 125l-Thrombin by the Rabbit Thoracic Aorta In Vitro: Permeability of the Endothelium, Intima-Media and Adventitial Layers Academic Article
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Urokinase has direct catalytic activity against fibrinogen and renders it less clottable by thrombin. Academic Article
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Use of Hirulog in the prevention of venous thrombosis after major hip or knee surgery. Academic Article
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Using direct oral anticoagulants (DOACs) in cancer and other high-risk populations Academic Article
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Venous Limb Gangrene during Warfarin Treatment of Cancer-Associated Deep Venous Thrombosis Academic Article
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Venous and arterial thrombosis – pathogenesis and the rationale for anticoagulation Academic Article
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Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia Academic Article
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Venous thromboembolism management: where do novel anticoagulants fit? Academic Article
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Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface Academic Article
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Volutrauma activates the clotting cascade in the newborn but not adult rat Academic Article
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Von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: An impact of peripheral blasts Academic Article
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Withdrawal of warfarin after deep vein thrombosis Academic Article
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Ximelagatran or Warfarin for Stroke Prevention in Patients With Atrial Fibrillation? Academic Article
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Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure Academic Article
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[23] Platelet histidine-rich glycoprotein Academic Article
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α2-Macroglobulin Remains as Important as Antithrombin III for Thrombin Regulation in Cord Plasma in the Presence of Endothelial Cell Surfaces Academic Article
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γT
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