Journal article
Prevention of thrombus formation and growth by antithrombin III and heparin cofactor II-dependent thrombin inhibitors: Importance of heparin cofactor II
Abstract
Heparin (HEP) prevents thrombus formation (TF) and thrombus growth (TG), by accelerating thrombin (THR) inhibition by antithrombin III (ATIII). Recent studies suggest that dermatan sulphate which catalyzes thrombin inhibition by heparin cofactor II (HCII), can inhibit TF and TG as effectively as HEP. This study compared the antithrombotic effects of HEP and another agent, Sulodexide (SLX) which catalyzes thrombin inhibition by ATIII and HCII …
Authors
Buchanan MR; Liao P; Smith LJ; Ofosu FA
Journal
Thrombosis Research, Vol. 74, No. 5, pp. 463–475
Publisher
Elsevier
Publication Date
June 1994
DOI
10.1016/0049-3848(94)90267-4
ISSN
0049-3848