Journal article
Do Coagulation Screening Tests Detect Increased Generation of Thrombin and Plasmin in Sick Newborn Infants?
Abstract
BACKGROUND: Disseminated intravascular coagulation (DIC) is usually diagnosed in sick infants who have prolonged clotting times, depletion of platelets and coagulation factors, and elevated levels of fibrin derivatives. However, the diagnostic accuracy of abnormal coagulation profiles in neonates at risk of DIC has been uncertain. Since DIC is characterized by activation of both the coagulation and fibrinolytic systems, the objective of this …
Authors
Schmidt B; Vegh P; Johnston M; Andrew M; Weitz J
Journal
Thrombosis and Haemostasis, Vol. 69, No. 05, pp. 418–421
Publisher
Thieme
Publication Date
1993
DOI
10.1055/s-0038-1651626
ISSN
0340-6245
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Antithrombin IIIBlood Coagulation TestsCohort StudiesDisseminated Intravascular CoagulationFibrin Fibrinogen Degradation ProductsFibrinogenFibrinolysinFibrinopeptide BHumansInfant, NewbornInfant, Newborn, DiseasesIntensive Care, NeonatalNeonatal ScreeningPeptide HydrolasesPlatelet CountPredictive Value of TestsProspective StudiesProthrombin TimeThrombinTreatment Outcome